{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T11:44:32Z","timestamp":1783943072105,"version":"3.55.0"},"reference-count":35,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2012,6,19]],"date-time":"2012-06-19T00:00:00Z","timestamp":1340064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background and Aim:\u2002<\/jats:bold> Traditionally the most common gastric polyps are hyperplastic polyps (HPs). However, in the last two decades, fundic gland polyps (FGPs) have greatly increased in Western countries. We aimed to re\u2010evaluate and compare the distribution of gastric polyps in a northern Chinese population in 2000 and 2010.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Consecutive patients with gastric polyps detected in 2000 and 2010 were analyzed and biopsies were re\u2010evaluated. Data including patients' age, sex, symptoms and the number, size, location, <jats:italic>Helicobacter pylori<\/jats:italic> (<jats:italic>H.\u2003pylori<\/jats:italic>) infection of polyps were recorded.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> A total of 6784 and 17\u2003337 patients underwent esophagogastroduodenoscopy in 2000 and 2010, 68 and 183 patients were diagnosed with gastric polyps, respectively. <jats:italic>H.\u2003pylori<\/jats:italic> infection decreased from 54.4% to 37.7% (<jats:italic>P<\/jats:italic>\u2003=\u20030.017). Overall, spectrum of gastric polyps changed (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.001). HPs accounted for 28.3% and decreased from 48.5% to 20.8%, adenoma\/carcinoma and inflammatory polyps also decreased. FGPs were present in 50.6% and increased from 8.8% to 66.1%. The location of polyps was also changed with an increase of polyps in gastric corpus. There was a high proportion of FGPs in females, while adenomas\/adenocarcinomas were more common in males. The distribution pattern was similar in young and elderly patients.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> Spectrum change of gastric polyps was observed over the past 10\u2003years in the northern Chinese population most likely due to the higher proportion of FGPs. Further studies are required to investigate the reasons and confirm whether it will lead to a different management strategy in China.<\/jats:p>","DOI":"10.1111\/j.1440-1746.2012.07116.x","type":"journal-article","created":{"date-parts":[[2012,3,13]],"date-time":"2012-03-13T16:42:48Z","timestamp":1331656968000},"page":"1175-1180","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":64,"title":["Distribution trends of gastric polyps: An endoscopy database analysis of 24\u2003121 northern Chinese patients"],"prefix":"10.1111","volume":"27","author":[{"given":"Hailong","family":"Cao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bangmao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,6,19]]},"reference":[{"key":"e_1_2_7_2_2","first-page":"775","volume-title":"Pathologic Basis of Disease","author":"Crawford JM","year":"1999"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2009.182089"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-198902000-00028"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-28032007000100004"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1009061"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.139"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2009.70"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-009-0993-z"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.14.1318"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2006.03127.x"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-5378.2008.00631.x"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2009.06188.x"},{"key":"e_1_2_7_14_2","first-page":"572","article-title":"Analysis on the current use and trend of drugs for digestive system through comprehensive statistics index, in Hangzhou","volume":"31","author":"Chen XY","year":"2010","journal-title":"Zhonghua Liu Xing Bing Xue Za Zhi"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-5378.2007.00487.x"},{"key":"e_1_2_7_16_2","first-page":"1759","article-title":"Recent changes in the prevalence of Helicobacter pylori infection among children and adults in high\u2010 or low\u2010incidence regions of gastric cancer in China","volume":"122","author":"Zhang DH","year":"2009","journal-title":"Chin. 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