{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T13:23:00Z","timestamp":1760016180005},"reference-count":16,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2012,10,29]],"date-time":"2012-10-29T00:00:00Z","timestamp":1351468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2012,11]]},"abstract":"Abstract<\/jats:title>Background and Aim<\/jats:title>Though angiographic embolization (AE<\/jats:styled-content>) is a type of effective treatment modality for duodenal ulcer bleeding, the optimum time at which to perform the procedure, early or delayed, is unknown. The authors compared the prognosis of early AE<\/jats:styled-content> (EAE<\/jats:styled-content>) and delayed AE<\/jats:styled-content> (DAE<\/jats:styled-content>) in patients with duodenal ulcer bleeding.<\/jats:p><\/jats:sec>Methods<\/jats:title>A total of 54 patients with duodenal ulcer bleeding were evaluated with first\u2010look endoscopy followed by AE<\/jats:styled-content>. The patients were divided into two groups, the EAE<\/jats:styled-content> group and DAE<\/jats:styled-content> group, according to endoscopic attempts to stop the bleeding during the first\u2010look endoscopy.<\/jats:p><\/jats:sec>Results<\/jats:title>The success rate of AE<\/jats:styled-content>, rebleeding rate, and number of patients who underwent surgery was not significantly different between the EAE<\/jats:styled-content> group and DAE<\/jats:styled-content> group (91.3% vs<\/jats:italic> 93.5%, 21.7% vs<\/jats:italic> 29.0% and 4.3% vs<\/jats:italic> 16.1%, respectively; P<\/jats:italic>\u2009>\u20090.05). With respect to death and intensive care unit (ICU<\/jats:styled-content>) care rate, multivariate analysis showed more favorable results in the EAE<\/jats:styled-content> group (0% vs<\/jats:italic> 22.6%, P<\/jats:italic>\u2009=\u20090.016 and 4.3% vs<\/jats:italic> 57.4%, P<\/jats:italic>\u2009=\u20090.003, respectively). Multivariate analysis also showed that prolonged prothrombin time (PT<\/jats:styled-content>)\u2009>\u20091.2 international normalized ratio and the endoscopic attempt were independent factors associated with ICU<\/jats:styled-content> care.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>When the AE<\/jats:styled-content> was performed early with correction for prolonged PT<\/jats:styled-content>, the patients with duodenal ulcer bleeding had a more favorable prognosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1440-1746.2012.07239.x","type":"journal-article","created":{"date-parts":[[2012,7,31]],"date-time":"2012-07-31T16:22:32Z","timestamp":1343751752000},"page":"1670-1674","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Early angiographic embolization is more effective than delayed angiographic embolization in patients with duodenal ulcer bleeding"],"prefix":"10.1111","volume":"27","author":[{"given":"Seok","family":"Lee","sequence":"first","affiliation":[{"name":"Aerospace Medical Center Republic of Korea Air Force Cheongwon\u2010gun Chungcheongbuk\u2010do Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Wook","family":"Kim","sequence":"additional","affiliation":[{"name":"Research Institute of Clinical Medicine of Chonbuk National University Hospital\u2010Chonbuk National University Jeonju Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Chang","family":"Moon","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine of Chonbuk National University Hospital\u2010Chonbuk National University Jeonju Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Won","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine of Chonbuk National University Hospital\u2010Chonbuk National University Jeonju Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heyoung Il","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine of Chonbuk National University Hospital\u2010Chonbuk National University Jeonju Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won Seok","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Daejeon St. Mary's Hospital Daejeon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Byung Jun","family":"Jeon","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine of Chonbuk National University Hospital\u2010Chonbuk National University Jeonju Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Youn","family":"Sohn","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine of Chonbuk National University Hospital\u2010Chonbuk National University Jeonju Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seong Hun","family":"Kim","sequence":"additional","affiliation":[{"name":"Research Institute of Clinical Medicine of Chonbuk National University Hospital\u2010Chonbuk National University Jeonju Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In Hee","family":"Kim","sequence":"additional","affiliation":[{"name":"Research Institute of Clinical Medicine of Chonbuk National University Hospital\u2010Chonbuk National University Jeonju Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung Ok","family":"Lee","sequence":"additional","affiliation":[{"name":"Research Institute of Clinical Medicine of Chonbuk National University Hospital\u2010Chonbuk National University Jeonju Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo Teik","family":"Lee","sequence":"additional","affiliation":[{"name":"Research Institute of Clinical Medicine of Chonbuk National University Hospital\u2010Chonbuk National University Jeonju Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,10,29]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.143.2.6978500"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1005436"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(86)90097-1"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1005697"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2005.11.048"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1148\/102.2.303"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2007.10.018"},{"key":"e_1_2_5_9_1","first-page":"519","article-title":"Factors predicting incomplete endoscopic attempt in bleeding gastroduodenal ulcers","volume":"57","author":"Urayama 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