{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:50:29Z","timestamp":1761630629028},"reference-count":31,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2012,11,20]],"date-time":"2012-11-20T00:00:00Z","timestamp":1353369600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2012,12]]},"abstract":"Abstract<\/jats:title>Background and Aim<\/jats:title>Performance of double balloon enteroscopy (DBE<\/jats:styled-content>) on older patients with comorbidities is a matter of safety. We aimed to investigate the utility and safety of DBE<\/jats:styled-content> in older patients.<\/jats:p><\/jats:sec>Methods<\/jats:title>We retrospectively reviewed the medical records of patients 75 years or older who underwent DBE<\/jats:styled-content> in our open\u2010access endoscopy unit in a tertiary center. We analyzed the diagnostic yield, therapeutic intervention, and safety including complications of DBE<\/jats:styled-content>.<\/jats:p><\/jats:sec>Results<\/jats:title>Four scheduled DBE<\/jats:styled-content>s were canceled because of poor conditions. Two hundred and fourteen DBEs<\/jats:styled-content> were performed in 167 elderly patients. All DBE<\/jats:styled-content>s were performed under monitored anesthesia care using intravenous propofol administered by anesthesiologists. One half of the patients were male (female\u2009:\u2009male\u2009=\u200980:87). The mean age of patients was 80.1\u2009\u00b1\u20093.7 years. Co\u2010morbidity of significant chronic diseases was noted in 208 (97.2%) DBEs<\/jats:styled-content>. Fifty\u2010one (23.8%) DBE<\/jats:styled-content>s were performed in patients with American Society of Anesthesiologists (ASA<\/jats:styled-content>) physical status II<\/jats:styled-content>, 151 (70.6%) DBEs<\/jats:styled-content> with ASA<\/jats:styled-content> class III<\/jats:styled-content>, and 12 (5.6%) DBE<\/jats:styled-content>s with ASA<\/jats:styled-content> class IV<\/jats:styled-content>. The most common indication was obscure gastrointestinal bleeding. The mean DBE<\/jats:styled-content> procedure time was 131\u2009\u00b1\u200951\u2009min. Abnormalities were detected in 129 (60.3%) DBE<\/jats:styled-content>s with therapeutic interventions performed in 83 (38.8%) cases. Pancreatitis, hypoxia, and aspiration pneumonia developed after three (1.4%), three (1.4%), and two (0.9%) DBE<\/jats:styled-content>s, respectively, all of which resolved with conservative care.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Double balloon enteroscopy can be done with acceptable safety in the elderly with high ASA<\/jats:styled-content> class. DBE<\/jats:styled-content> shows a high diagnostic yield and can deliver many therapeutic applications.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1440-1746.2012.07284.x","type":"journal-article","created":{"date-parts":[[2012,10,4]],"date-time":"2012-10-04T11:31:13Z","timestamp":1349350273000},"page":"1831-1836","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Double balloon enteroscopy can be safely done in elderly patients with significant co\u2010morbidities"],"prefix":"10.1111","volume":"27","author":[{"given":"Jeong\u2010Sik","family":"Byeon","sequence":"first","affiliation":[{"name":"David Geffen School of Medicine at UCLA Cedars\u2010Sinai Medical Center (CSMC) Los Angeles California USA"},{"name":"Asan Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neel K.","family":"Mann","sequence":"additional","affiliation":[{"name":"David Geffen School of Medicine at UCLA Cedars\u2010Sinai Medical Center (CSMC) Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laith H.","family":"Jamil","sequence":"additional","affiliation":[{"name":"David Geffen School of Medicine at UCLA Cedars\u2010Sinai Medical Center (CSMC) Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon K.","family":"Lo","sequence":"additional","affiliation":[{"name":"David Geffen School of Medicine at UCLA Cedars\u2010Sinai Medical Center (CSMC) Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,11,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1542-3565(04)00453-7"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-921188"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2007.05270.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2007.06.048"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-966190"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-966841"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2007.06.056"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e31818dd925"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.giec.2006.03.002"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2009.05.005"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2006.03.001"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-966444"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2009.10.054"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i22.2859"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2001-15313"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.317.7158.575"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-4943(03)00004-9"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2005.09.051"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-009-0784-6"},{"key":"e_1_2_6_21_1","unstructured":"American Society of Anesthesiologists.ASA Physical Status Classification System. 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