{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T18:17:35Z","timestamp":1791829055146,"version":"4.3.4"},"reference-count":49,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2007,7,19]],"date-time":"2007-07-19T00:00:00Z","timestamp":1184803200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Paediatrics Child Health"],"published-print":{"date-parts":[[2007,11]]},"abstract":"<jats:p><jats:bold>Aim:\u2003<\/jats:bold> Protein energy malnutrition is common in children with chronic renal failure (CRF) and may negatively impact on clinical outcome. Although the aetiology of malnutrition is multifactorial, descriptive information on body composition may guide nutritional interventions aimed at optimising nutritional status.<\/jats:p><jats:p><jats:bold>Methods:\u2003<\/jats:bold> This prospective cohort study in children with CRF was conducted from April 1999 to November 2000. Patients were categorised according to their glomerular filtration rate (GFR) into CRF and end\u2010stage renal failure (ESRF). Body composition was assessed based on anthropometry, total body potassium (TBK), total body protein (TBP) and dual X\u2010ray absorptiometry (DEXA).<\/jats:p><jats:p><jats:bold>Results:\u2003<\/jats:bold> Fifteen patients (10 male, 5 female; mean age: 13.4\u2003\u00b1\u20034.3\u2003years) were studied, including eight patients with CRF (mean GFR: 17.0\u2003\u00b1\u20037.2\u2003mL\/min\/1.73\u2003m<jats:sup>2<\/jats:sup>) and seven patients with ESRF (mean GFR: 6.4\u2003\u00b1\u20031.7\u2003mL\/min\/1.73\u2003m<jats:sup>2<\/jats:sup>). Patients in both groups (<jats:italic>n<\/jats:italic>\u2003=\u200315) had deficits in height and TBP (mean z\u2010score height\u2010for\u2010age: \u22121.19\u2003\u00b1\u20031.05, <jats:italic>P<\/jats:italic>\u2003&lt;\u20030.01; mean z\u2010score TBP: \u22120.71\u2003\u00b1\u20030.71, <jats:italic>P<\/jats:italic>\u2003&lt;\u20030.05). There were no significant differences in weight, height, fat\u2010free mass, TBK and TBP between patients with CRF and ESRF.<\/jats:p><jats:p><jats:bold>Conclusions:\u2003<\/jats:bold> Linear growth impairment and decreased TBP are common in children with chronic and ESRF. TBK and DEXA may underestimate the degree of malnutrition in these patients.<\/jats:p>","DOI":"10.1111\/j.1440-1754.2007.01167.x","type":"journal-article","created":{"date-parts":[[2007,7,19]],"date-time":"2007-07-19T09:32:24Z","timestamp":1184837544000},"page":"740-745","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Body composition of children with chronic and end\u2010stage renal failure"],"prefix":"10.1111","volume":"43","author":[{"given":"Andreas","family":"Nydegger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boyd JG","family":"Strauss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf G","family":"Heine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ninik","family":"Asmaningsih","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin L","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie E","family":"Bines","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,7,19]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/026010608700500407"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(12)70364-5"},{"key":"e_1_2_7_4_2","first-page":"S199","article-title":"Malnutrition as the main factor in morbidity and mortality of hemodialysis patients","volume":"16","author":"Acchiardo SR","year":"1983","journal-title":"Kidney Int. 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