{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T18:25:44Z","timestamp":1790101544159,"version":"4.0.1"},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,3,31]],"date-time":"2004-03-31T00:00:00Z","timestamp":1080691200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2004,4]]},"abstract":"<jats:title>SUMMARY:<\/jats:title><jats:p><jats:bold>Background:\u2003<\/jats:bold>  <jats:italic>Helicobacter pylori<\/jats:italic> has been reported to play an important role in the development of gastritis and gastric ulcer.<\/jats:p><jats:p><jats:bold>Methods:\u2003<\/jats:bold> This study included 168 patients with end\u2010stage renal disease (ESRD; 30 non\u2010dialysis patients, 138 patients receiving dialysis; mean duration of dialysis: 57.3\u2003\u00b1\u200361.7\u2003months) and 138 control volunteers. We investigated the prevalence of <jats:italic>H. pylori<\/jats:italic> infection by measuring <jats:italic>H. pylori<\/jats:italic> antibody (IgG) levels.<\/jats:p><jats:p><jats:bold>Results:\u2003<\/jats:bold> The prevalence of <jats:italic>H. pylori<\/jats:italic> infection was 62.3% in the control group, 53.3% in the non\u2010dialysis patients, and 36.9% in the dialysis patients. The percentage decreased with a reduction of renal function. In addition, the proportion of <jats:italic>H. pylori<\/jats:italic>\u2010positive patients decreased with the duration of dialysis, and the antibody titre was also significantly decreased. There was no association between long\u2010term oral administration of H2RA (H2 receptor antagonist) and the incidence of <jats:italic>H. pylori<\/jats:italic> infection.<\/jats:p><jats:p><jats:bold>Conclusion:\u2003<\/jats:bold> Among dialysis patients, the proportion of <jats:italic>H. pylori<\/jats:italic>\u2010positive patients was low. An aetiological factor other than H2RA agents was suggested. Renal failure or dialysis treatment may influence <jats:italic>H. pylori<\/jats:italic> infection.<\/jats:p>","DOI":"10.1111\/j.1440-1797.2004.00239.x","type":"journal-article","created":{"date-parts":[[2004,3,31]],"date-time":"2004-03-31T10:45:52Z","timestamp":1080729952000},"page":"73-76","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Prevalence of <i>Helicobacter pylori<\/i> antibodies in long\u2010term dialysis patients"],"prefix":"10.1111","volume":"9","author":[{"given":"FUMITAKA","family":"NAKAJIMA","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MASAHIRO","family":"SAKAGUCHI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HIROSHI","family":"OKA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YOSHIO","family":"KAWASE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"NOBUHISA","family":"SHIBAHARA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TORU","family":"INOUE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HARUHIKO","family":"UEDA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YOJI","family":"KATSUOKA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,3,31]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"157","article-title":"The gastrointestinal tract in uremic patients on long\u2010term hemodialysis","volume":"17","author":"Milito G","year":"1985","journal-title":"Kidney Int."},{"key":"e_1_2_5_3_2","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1128\/jcm.34.5.1147-1152.1996","article-title":"Evaluation of three commercial enzyme immunoassays compared with the 13C urea breath test for detection of Helicobacter pylori infection","volume":"34","author":"Marchildon PA","year":"1996","journal-title":"J. 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