{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T05:11:57Z","timestamp":1697260317646},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2004,6,4]],"date-time":"2004-06-04T00:00:00Z","timestamp":1086307200000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2004,6]]},"abstract":"<jats:title>SUMMARY:<\/jats:title><jats:p><jats:bold>Methods and Results:\u2003<\/jats:bold> In order to clarify the predialytic factors influencing the onset of secondary hyperparathyroidism (SHPT) in patients on chronic maintenance haemodialysis, the time\u2010course changes of serum levels of intact\u2010PTH (i\u2010PTH) during haemodialysis for 5\u2003years were investigated. The subjects were 69 non\u2010diabetic patients who had a serum aluminium level of less than 1.85 nmol\/L at the end of observation. Patients were divided into two groups based on i\u2010PTH levels obtained at the start of dialysis; the high group (H group) consisted of patients whose i\u2010PTH levels were more than 22.00\u2003pmol\/L, the low group (L group) had levels less than 22.00\u2003pmol\/L. In the H group, i\u2010PTH was 41.46\u2003\u00b1\u20032.87\u2003pmol\/L at the start of dialysis (<jats:italic>vs<\/jats:italic> L group, <jats:italic>P<\/jats:italic>\u2003&lt;\u20030.0001) and 15.82\u2003\u00b1\u20032.85\u2003pmol\/L after haemodialysis initiation. In the L group, i\u2010PTH levels did not significantly change and was 11.69\u2003\u00b1\u20032.50\u2003pmol\/L 12\u2003months after the start of dialysis (at the 12th month). However, at the 60th month, the i\u2010PTH level was 33.24\u2003\u00b1\u20035.30\u2003pmol\/L in the H group, and 9.85\u2003\u00b1\u20032.13\u2003pmol\/L in the L group (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.005).<\/jats:p><jats:p><jats:bold>Conclusion:\u2003<\/jats:bold> It is suggested that control of i\u2010PTH levels in the predialytic period may be important to suppress SHPT throughout haemodialysis.<\/jats:p>","DOI":"10.1111\/j.1440-1797.2004.00248.x","type":"journal-article","created":{"date-parts":[[2004,6,4]],"date-time":"2004-06-04T11:29:32Z","timestamp":1086348572000},"page":"161-166","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Relationship of predialytic intact parathyroid hormone on secondary hyperparathyroidism in chronic maintenance haemodialysis patients"],"prefix":"10.1111","volume":"9","author":[{"given":"SATOSHI","family":"ETOH","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"TOSHIAKI","family":"MURATA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YOSHIYUKI","family":"HASEGAWA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YOSHITO","family":"MIYAHARA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ATUNORI","family":"ISHIMURA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YASUHIRO","family":"ABE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RITSUYA","family":"NODA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SATORU","family":"OGAHARA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HIDETOSHI","family":"KANEOKA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"TAKAO","family":"SAITO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,6,4]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(97)90484-4"},{"key":"e_1_2_6_3_2","first-page":"1751","article-title":"Identification of risk factors on secondary hyperparathyroidism undergoing long\u2010term haemodialysis with vitamin D3","volume":"9","author":"Mizumoto D","year":"1994","journal-title":"Nephrol. 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