{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T03:10:20Z","timestamp":1736565020825,"version":"3.32.0"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,9,29]],"date-time":"2006-09-29T00:00:00Z","timestamp":1159488000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Nephrology"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:title>SUMMARY:<\/jats:title><jats:p><jats:bold>Background:\u2003<\/jats:bold>Generation of reactive oxygen specimens is the basic mechanism leading to ischaemia\/reperfusion injury of the kidney graft. Oxygen burst is a trigger for sophisticated biochemical changes leading to generation of oxygenated lipids and changes in microcirculation, which recruit recipient\u2019s neutrophils and contribute to delayed graft function. It has been shown that the free radicals generation correlates with the activity of anti\u2010oxidative system. Superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and glutathione (GSH) are involved in protection against free radicals.<\/jats:p><jats:p><jats:bold>Aim:\u2003<\/jats:bold>To examine the activity of erythrocyte anti\u2010oxidative system during reperfusion of the transplanted kidney allograft.<\/jats:p><jats:p><jats:bold>Methods:\u2003<\/jats:bold>The study included 40 renal transplant recipients. Blood was taken from the iliac vein before transplantation and from the graft\u2019s renal vein immediately, as well as 2 and 4\u2003min after total reperfusion. The authors assessed the process of reperfusion using ThermaCAM SC500 termovision camera. Spectrophotometric methods were used to measure superoxide dismutase, glutathione peroxidase and catalase activity as well as glutathione concentrations in erythrocytes.<\/jats:p><jats:p><jats:bold>Results:\u2003<\/jats:bold>There were no statistically significant differences in the activities of superoxide dismutase, catalase and glutathione peroxidase as well as glutathione concentrations during the first 4\u2003min after total graft reperfusion. Nevertheless, there was a positive correlation between the activity of superoxide dismutase and glutathione peroxidase.<\/jats:p><jats:p><jats:bold>Conclusion:\u2003<\/jats:bold>The results suggest that the erythrocyte anti\u2010oxidative system is stable during the early phase after reperfusion. An association between some anti\u2010oxidative enzymes was noted.<\/jats:p>","DOI":"10.1111\/j.1440-1797.2006.00672.x","type":"journal-article","created":{"date-parts":[[2006,9,29]],"date-time":"2006-09-29T15:43:13Z","timestamp":1159544593000},"page":"467-470","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Early phase of reperfusion of human kidney allograft does not affect an erythrocyte anti\u2010oxidative system"],"prefix":"10.1111","volume":"11","author":[{"given":"LESZEK","family":"DOMA\u0143SKI","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BARBARA","family":"DO\u0141 GOWSKA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KRZYSZTOF","family":"SAFRANOW","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MAREK","family":"MY\u015aLAK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JACEK","family":"R\u00d3\u017bA\u0143SKI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MACIEJ","family":"ROMANOWSKI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MAREK","family":"OSTROWSKI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MACIEJ","family":"DOMA\u0143SKI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ANDRZEJ","family":"PAWLIK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KAZIMIERZ","family":"CIECHANOWSKI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,9,29]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(00)02341-1"},{"key":"e_1_2_6_3_2","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1681\/ASN.V125973","article-title":"De novo demonstration and co\u2010localisation of free\u2010radical production and apoptosis formation in kidney subjected to ischemia\/reperfusion","volume":"12","author":"Chien CT","year":"2001","journal-title":"J. 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