{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T23:05:25Z","timestamp":1793142325840,"version":"4.5.0"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,1,28]],"date-time":"2005-01-28T00:00:00Z","timestamp":1106870400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatry Clin Neurosci"],"published-print":{"date-parts":[[2005,2]]},"abstract":"<jats:p><jats:bold>Abstract\u2002<\/jats:bold> The uses of lorazepam and electroconvulsive therapy (ECT) have been proven to be effective in treating catatonia. In the present study a modified treatment strategy (i.e. lorazepam i.m. injection or diazepam infused i.v. if lorazepam failed, not with ECT) was proposed to rapidly relieve catatonic signs in patients with schizophrenia. During a 3\u2010year period, 14 patients with catatonic schizophrenia in Chinese ethnic background Taiwanese were brought to the emergency unit of a general hospital. First, the patients were immediately treated with lorazepam 1 or 2\u2003ampules (2\u2003mg\/mL per ampule) i.m. injection (IMI) during 2\u2003h. Second, if the previous 2\u2003ampules of lorazepam IMI failed, diazepam infused i.v. (10\u2003mg\/2\u2003mL per ampule) in normal saline 500\u2003mL every 8\u2003h would be done during 1\u2003day. The response rate of catatonic signs in these 14 patients with lorazepam IMI during the first 2\u2003h was 85.7% (12\/14). However, according to the results of this method, the total response rate to benzodiazepines during 1\u2003day was 100%(14\/14). These results suggested that this modified treatment strategy could rapidly and completely relieve catatonic signs, even without the use of ECT.<\/jats:p>","DOI":"10.1111\/j.1440-1819.2005.01331.x","type":"journal-article","created":{"date-parts":[[2005,1,28]],"date-time":"2005-01-28T15:13:33Z","timestamp":1106925213000},"page":"52-55","source":"Crossref","is-referenced-by-count":38,"title":["Lorazepam and diazepam rapidly relieve catatonic signs in patients with schizophrenia"],"prefix":"10.1111","volume":"59","author":[{"given":"TIAO\u2010LAI","family":"HUANG","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,1,28]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-89-1-74"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.3109\/00048679609076085"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.137.8.983"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.2.433"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1977.01770200085010"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.158.3.419"},{"key":"e_1_2_6_8_2","first-page":"21","article-title":"Fatal pulmonary embolism in the catatonic syndrome: two cases and a literature review","volume":"56","author":"McCall WV","year":"1995","journal-title":"J. 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