{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T09:15:39Z","timestamp":1759482939938},"reference-count":32,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2004,9,3]],"date-time":"2004-09-03T00:00:00Z","timestamp":1094169600000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathology International"],"published-print":{"date-parts":[[2004,9]]},"abstract":"<jats:p>A case of small intestinal extranodal marginal zone B\u2010cell lymphoma of mucosa\u2010associated lymphoid tissue (MALT lymphoma) with monoclonal cryoglobulinemia is described. The patient was a woman in her mid\u2010sixties with purpura of the bilateral lower legs and abdominal pain. An immunoserological investigation showed expression of IgM\u2010kappa type monoclonal cryoglobulin. A renal biopsy specimen revealed proliferative glomerulonephritis with cryoglobulin deposition. Physical examination disclosed a stenosis, edematous changes and ascariasis in the small intestine. In aspiration cytology of the ascites, proliferation of the atypical lymphoid cells with plasmacytoid differentiation was observed. These cells were positive for B\u2010lineage antigens in immunocytochemistry, and showed an immunoglobulin heavy\u2010chain gene rearrangement in Southern blotting and chromosomal alteration in G\u2010banded karyotype analysis. Although medicinal treatment was used, the patient died of general prostration. The diagnosis of intestinal MALT lymphoma was made at autopsy. Expression of API2\u2010MALT1 fusion transcripts was detected by reverse transcription\u2013polymerase chain reaction analysis using formalin\u2010fixed, paraffin\u2010embedded tissue. Intestinal MALT lymphomas with API2\u2010MALT1 expression have distinctive forms of infiltration compared with those without translocation. Therefore, detection of API2\u2010MALT1 fusion transcripts is useful for evaluating the prognosis and clinical behavior of the disease.<\/jats:p>","DOI":"10.1111\/j.1440-1827.2004.01684.x","type":"journal-article","created":{"date-parts":[[2004,9,3]],"date-time":"2004-09-03T08:57:35Z","timestamp":1094201855000},"page":"712-718","source":"Crossref","is-referenced-by-count":9,"title":["Extranodal marginal zone B\u2010cell lymphoma of mucosa\u2010associated lymphoid tissue (MALT lymphoma) arising in the small intestine with monoclonal cryoglobulinemia"],"prefix":"10.1111","volume":"54","author":[{"given":"Tadashi","family":"Saito","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun\u2010ichi","family":"Tamaru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirohisa","family":"Kishi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junko","family":"Kayao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiko","family":"Kuzuu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisashi","family":"Wakita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Adachi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Itoyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ittaku","family":"Mikata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,9,3]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.138.7.1158"},{"key":"e_1_2_5_3_2","first-page":"743","article-title":"Localized extranodal non\u2010Hodgkin's lymphoma of the gastrointestinal tract: Sheffield Lymphoma Group experience","volume":"18","author":"Koh PK","year":"2001","journal-title":"Int J Oncol"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2000.t01-1-01781.x"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(98)90211-8"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(99)00069-8"},{"key":"e_1_2_5_7_2","first-page":"3944","article-title":"The t(11;18)(q21;q21) chromosome translocation is a frequent and specific aberration in low\u2010grade but not high\u2010grade malignant non\u2010Hodgkin's lymphomas of the mucosa\u2010associated lymphoid tissue (MALT) type","volume":"57","author":"Ott G","year":"1997","journal-title":"Cancer Res"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.56.1.36"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)64988-7"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00019606-199503000-00007"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)64012-6"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)63908-9"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(74)90852-3"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(80)90390-3"},{"key":"e_1_2_5_15_2","first-page":"87","article-title":"Cryoimmunoglobulins","volume":"10","author":"Grey HM","year":"1973","journal-title":"Semin Hematol"},{"key":"e_1_2_5_16_2","first-page":"691","article-title":"Purification of cold agglutinins from patients with chronic cold haemagglutinin disease. 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