{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:34:44Z","timestamp":1782603284319,"version":"3.54.5"},"reference-count":16,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2004,10,7]],"date-time":"2004-10-07T00:00:00Z","timestamp":1097107200000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathology International"],"published-print":{"date-parts":[[2004,10]]},"abstract":"<jats:p>Lipoleiomyoma is a rare uterine tumor. The exact frequency and proliferation activity are not yet known. This study aims to know the frequency and evaluate the relation with renal angiomyolipoma. Lipoleiomyoma cases were immunohistochemically stained by antibodies for Ki\u201067, melanoma specific antigen HMB45, S\u2010100 protein, and \u03b1 smooth muscle actin (\u03b1\u2010SMA). Frequency of uterine lipoleiomyoma among \u200auterine \u200amyomatous \u200atumor \u200awas \u200a17\/4904 \u200a(0.35%) \u200ain the Department of Human Pathology, Field of Oncology, Kagoshima University Graduate School database (1983\u20132003). Patients ranged from 45 to 74\u2003years of age, and 10 cases were associated with leiomyoma. Six of 17 (35%) cases showed areas with renal angiomyolipoma\u2010like vessels and atypical cellular features. Immunostaining was available in 12 cases. By Ki\u201067 labeling index, both muscle (average 1.38%) and fat (average 1.17%) portions of the tumor had greater proliferation than normal myometrium (average 0.76%), which suggests that fat portions of the tumor are proliferating adipose tissue rather than fatty degeneration of muscular counterpart. HMB45 antigen, which is positive in renal angiomyolipoma, was negative in three uterine cases having angiomyolipoma\u2010like vessels (3\/12). However, HMB45 antigen was positive in spindle\u2010shaped tumor cells of three cases (3\/12) which lacked angiomyolipoma\u2010like vessels. Presence of angiomyolipoma\u2010like blood vessels in these tumors is not an uncommon feature. However, the diagnosis of uterine angiomyolipoma should not be based on the result of HMB45 antigen immunoreactivity alone.<\/jats:p>","DOI":"10.1111\/j.1440-1827.2004.01748.x","type":"journal-article","created":{"date-parts":[[2004,10,7]],"date-time":"2004-10-07T15:00:41Z","timestamp":1097161241000},"page":"751-758","source":"Crossref","is-referenced-by-count":51,"title":["Uterine lipoleiomyoma: A histopathological review of 17 cases"],"prefix":"10.1111","volume":"54","author":[{"given":"Thida","family":"Aung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masamichi","family":"Goto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuharu","family":"Nomoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Kitajima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsutomu","family":"Douchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuhiro","family":"Yoshinaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suguru","family":"Yonezawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,10,7]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00507135"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1827.2001.01289.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02899067"},{"key":"e_1_2_6_5_2","first-page":"228","volume-title":"Pathology in Gynaecology and Obstetrics","author":"Gompel C","year":"1994"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.2002.01320.x"},{"key":"e_1_2_6_7_2","volume-title":"Tumors of the Kidney, Bladder and Related Structures.","author":"Murphy WM","year":"1994"},{"key":"e_1_2_6_8_2","first-page":"164","article-title":"Atypical lipoleiomyoma of the uterus","volume":"41","author":"Lin M","year":"1999","journal-title":"Acta Pathol Jpn"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004347-200304000-00016"},{"key":"e_1_2_6_10_2","first-page":"842","article-title":"Angiomyolipomas: The nature and expression of the HMB45 antigen","volume":"7","author":"Sturtz CL","year":"1994","journal-title":"Mod Pathol"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.1996.tb03644.x"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.35.12.1380"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.10057"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199909000-00003"},{"key":"e_1_2_6_15_2","first-page":"37","article-title":"Clinicopathologic analysis of renal and extrarenal angiomyolipomas: Report of 44 cases","volume":"63","author":"Huang PC","year":"2000","journal-title":"Zhonghua Yi Xue Za Zhi (Taipei)"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200201000-00001"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200402000-00013"}],"container-title":["Pathology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1440-1827.2004.01748.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1440-1827.2004.01748.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T17:24:25Z","timestamp":1696872265000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1440-1827.2004.01748.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,10]]},"references-count":16,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2004,10]]}},"alternative-id":["10.1111\/j.1440-1827.2004.01748.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1440-1827.2004.01748.x","archive":["Portico"],"relation":{},"ISSN":["1320-5463","1440-1827"],"issn-type":[{"value":"1320-5463","type":"print"},{"value":"1440-1827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,10]]}}}