{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T19:39:13Z","timestamp":1697312353883},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,12,21]],"date-time":"2011-12-21T00:00:00Z","timestamp":1324425600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:bold>Background and objective:\u2003<\/jats:bold> Community\u2010acquired pneumonia (CAP) is generally considered to be a major cause of morbidity and mortality. There is much controversy regarding the optimal choice of antibiotics for patients with CAP. The aim of this study was to identify the antibiotics prescribed for adults hospitalized with CAP in Korea during a calendar year.<\/jats:p><jats:p><jats:bold>Methods:\u2003<\/jats:bold> This population\u2010based, descriptive epidemiological study was performed using data from nationwide health insurance claims from 1 January 2004 to 31 December 2004. The study population was adults (\u226518\u2003years old), who had been hospitalized with CAP as determined by discharge diagnosis, and who had been treated with antibiotics for \u22653 days. The exclusion criteria were tuberculosis, underlying malignancies and potential nosocomial pneumonia, based on the department providing care, or surgery reports during the admission.<\/jats:p><jats:p><jats:bold>Results:\u2003<\/jats:bold> Of the 5592 adults hospitalized with CAP, data for 3662 (65.5%) patients was eligible for inclusion in the analysis. This included data for 1899 (51.9%) males, and 2045 (55.8%) patients \u226565\u2003years of age. The most frequently prescribed antimicrobial regimen was \u03b2\u2010lactam\/\u03b2\u2010lactamase inhibitors and fluoroquinolones in combination (31.0%), followed by \u03b2\u2010lactam\/\u03b2\u2010lactamase inhibitors plus macrolides (30.2%), monotherapy (17.0%), \u03b2\u2010lactam\/\u03b2\u2010lactamase inhibitors plus aminoglycosides (12.9%), \u03b2\u2010lactam\/\u03b2\u2010lactamase inhibitors plus clindamycin (4.9%), and cephalosporins plus fluoroquinolones (2.5%). Monotherapy included, in decreasing order of use, cephalosporins (6.0%), fluoroquinolones (3.5%), \u03b2\u2010lactam\/\u03b2\u2010lactamase inhibitors (2.3%) and macrolides (2.2%).<\/jats:p><jats:p><jats:bold>Conclusions:\u2003<\/jats:bold> In this study, patterns of antimicrobial prescription for patients hospitalized with CAP were assessed for the first time in Korea. There was divergence from the 2009 Korean guidelines for the treatment of CAP, reinforcing the need for assessment of physicians' adherence to the guidelines.<\/jats:p>","DOI":"10.1111\/j.1440-1843.2011.02077.x","type":"journal-article","created":{"date-parts":[[2011,10,13]],"date-time":"2011-10-13T13:19:23Z","timestamp":1318511963000},"page":"172-179","source":"Crossref","is-referenced-by-count":6,"title":["Prescription of antibiotics for adults hospitalized with community\u2010acquired pneumonia in Korea in 2004: A population\u2010based descriptive study"],"prefix":"10.1111","volume":"17","author":[{"given":"YOUNG KYUNG","family":"YOON","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"EUN JU","family":"KIM","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BYUNG CHUL","family":"CHUN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JOONG SIK","family":"EOM","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DAE WON","family":"PARK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JANG WOOK","family":"SOHN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MIN JA","family":"KIM","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,12,21]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(01)01028-2"},{"key":"e_1_2_6_3_2","first-page":"1","article-title":"A prospective multicenter study of community\u2010cquired pneumonia in adults with emphasis on bacterial etiology","volume":"33","author":"Woo JH","year":"2001","journal-title":"Infect. 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