{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T09:38:38Z","timestamp":1791020318482,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2007,1,30]],"date-time":"2007-01-30T00:00:00Z","timestamp":1170115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2007,4]]},"abstract":"<jats:title>A<jats:sc>bstract<\/jats:sc><\/jats:title><jats:p><jats:bold>Background:\u2003<\/jats:bold> The objective of this study is to investigate the acute histological effects of transscleral cyclophotocoagulation and endoscopic cyclophotocoagulation on the ciliary body and other structures of porcine eyes compared with untreated controls.<\/jats:p><jats:p><jats:bold>Methods:\u2003<\/jats:bold> Transscleral cyclophotocoagulation and endoscopic cyclophotocoagulation were performed on porcine eyes. Detailed histological evaluations were performed with light and scanning electron microscopy of treated eyes and compared with untreated controls.<\/jats:p><jats:p><jats:bold>Results:\u2003<\/jats:bold> Histological changes were observed with both light and scanning electron microscopy for all treated tissues. Tissue treated with transscleral cyclophotocoagulation showed pronounced tissue disruption of the ciliary body muscle and stroma, ciliary processes, and both pigmented and non\u2010pigmented ciliary epithelium. Endoscopic cyclophotocoagulation\u2010treated tissue exhibited pronounced contraction of the cilliary processes with disruption of the ciliary body epithelium, with less architectural disorginization and sparing of the ciliary body muscle. The sclera was not affected by either laser treatment.<\/jats:p><jats:p><jats:bold>Conclusion:\u2003<\/jats:bold> The endoscopic cyclophotocoagulation treatment caused less damage to the ciliary body compared with the transscleral cyclophotocoagulation when evaluated by light and scanning electron microscopy. Compared with transscleral cyclophotocoagulation, endoscopic cyclophotocoagulation appears to be a more selective form of cyclophotocoagulation resulting in less tissue disruption while achieving the goal of destroying ciliary body epithelium.<\/jats:p>","DOI":"10.1111\/j.1442-9071.2006.01415.x","type":"journal-article","created":{"date-parts":[[2007,2,2]],"date-time":"2007-02-02T18:23:27Z","timestamp":1170440607000},"page":"270-274","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":62,"title":["Comparison of acute structural and histopathological changes of the porcine ciliary processes after endoscopic cyclophotocoagulation and transscleral cyclophotocoagulation"],"prefix":"10.1111","volume":"35","author":[{"given":"Mina B","family":"Pantcheva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malik Y","family":"Kahook","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel S","family":"Schuman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc W","family":"Rubin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J","family":"Noecker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,1,30]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(96)30508-3"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(97)30109-2"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00061198-199902000-00003"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.84.9.999"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ijg.0000151890.41239.c5"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)71696-4"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-002-0508-5"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-4182(04)80140-6"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6701875"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(86)33662-5"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(88)32963-5"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(92)31718-X"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.86.12.1434"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.86.4.381"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1991.01080110070037"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00061198-199704000-00011"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(01)00889-2"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(02)01858-4"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1067\/mpa.2001.116868"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/00061198-199906000-00005"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1091-8531(99)70057-1"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(01)01359-9"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(99)00141-8"},{"key":"e_1_2_6_25_2","first-page":"2157","article-title":"Endoscopic cyclophotocoagulation for the treatment in glaucoma in keratoplasty patients","volume":"39","author":"Lin SC","year":"1998","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_6_26_2","first-page":"274","article-title":"Transscleral cyclophotocoagulation using a semiconductor diode laser in cadaver eyes","volume":"22","author":"Hennis HL","year":"1991","journal-title":"Ophthalmic Surg"},{"key":"e_1_2_6_27_2","first-page":"638","article-title":"Transscleral cyclophotocoagulation of human autopsy and monkey eyes","volume":"22","author":"Coleman AL","year":"1991","journal-title":"Ophthalmic Surg"},{"key":"e_1_2_6_28_2","doi-asserted-by":"crossref","first-page":"495","DOI":"10.3928\/1542-8877-19970601-09","article-title":"Transscleral diode laser cyclophotocoagulation on autopsy eyes with abnormally thinned sclera","volume":"28","author":"Palmer DJ","year":"1997","journal-title":"Ophthalmic Surg Lasers"}],"container-title":["Clinical &amp; 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