{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T18:09:26Z","timestamp":1789063766970,"version":"build-2803163510"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,7,25]],"date-time":"2012-07-25T00:00:00Z","timestamp":1343174400000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:title>A<jats:sc>bstract<\/jats:sc><\/jats:title><jats:p><jats:bold>Background:\u2002<\/jats:bold> To evaluate the clinical safety and efficacy of implanted Ferrara intrastromal corneal ring segments in a large sample of patients with ectatic corneal disease.<\/jats:p><jats:p><jats:bold>Design:\u2002<\/jats:bold> Retrospective, consecutive case series.<\/jats:p><jats:p><jats:bold>Samples:\u2002<\/jats:bold> A total of 1073 eyes of 810 patients consecutively operated from January 2006 to July 2008 were evaluated.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Two groups were created according to the type of ring implanted: Group 1 \u2013 patients implanted with the 160\u00b0 of arc ring \u2013 and Group 2 \u2013 patients implanted with the 210\u00b0 of arc ring.<\/jats:p><jats:p><jats:bold>Main Outcome Measures:\u2002<\/jats:bold> Uncorrected visual acuity, best\u2010corrected visual acuity, keratometry, asphericity and pachymetry at the thinnest point of the cornea. All patients were evaluated using a corneal tomography (Pentacam, Oculus, Inc., Lynnwood, WA, USA).<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> For Group 1 patients, uncorrected visual acuity increased to 20\/80, best\u2010corrected visual acuity increased to 20\/40, asphericity decreased to \u22120.35, spherical equivalent decreased to \u22122.26\u2003D and keratometry decreased to 45.72\u2003D (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.001 for each compared with preoperative values). For Group 2 patients, uncorrected visual acuity increased to 20\/130, best\u2010corrected visual acuity increased to 20\/60, asphericity decreased to \u22120.56, spherical equivalent decreased to \u22124.14\u2003D and keratometry decreased to 48.10\u2003D (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.001 for each compared with preoperative values). The 210\u00b0 intrastromal corneal ring segments reduced keratometry and asphericity more than the 160\u00b0 intrastromal corneal ring segments did. The complication rate was 3.82%.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> Ferrara intrastromal corneal ring segments implantation is safe and effective and has a low complication rate. It can effectively reduce the corneal steepening and improve uncorrected visual acuity and best\u2010corrected visual acuity in patients with keratoconus.<\/jats:p>","DOI":"10.1111\/j.1442-9071.2011.02698.x","type":"journal-article","created":{"date-parts":[[2011,9,8]],"date-time":"2011-09-08T17:41:13Z","timestamp":1315503673000},"page":"433-439","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Intrastromal corneal ring segments: visual outcomes from a large case series"],"prefix":"10.1111","volume":"40","author":[{"given":"Guilherme","family":"Ferrara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Torquetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo","family":"Ferrara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas","family":"Merayo\u2010Lloves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,7,25]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"577","article-title":"T\u00e9cnica cir\u00fargica para corre\u00e7\u00e3o de miopia; Anel corneano intra\u2010estromal. (Myopia correction with intrastromal corneal ring)","volume":"54","author":"Ferrara de A","year":"1995","journal-title":"Rev Bras Oftalmol"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(02)01495-5"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2003.12.005"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2009.04.035"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2009.05.036"},{"key":"e_1_2_5_7_2","first-page":"27","article-title":"Ferrara ring. An overview","author":"Ferrara P","year":"2009","journal-title":"Cataract Refract Surg Today Eur"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(02)02038-2"},{"key":"e_1_2_5_9_2","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3928\/1081-597X-20020101-06","article-title":"Management of corneal ectasia after laser in situ keratomileusis with INTACS","volume":"18","author":"Siganos CS","year":"2002","journal-title":"J Refract Surg"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-27492000000300008"},{"key":"e_1_2_5_11_2","doi-asserted-by":"crossref","first-page":"20","DOI":"10.3928\/1081-597X-19960101-08","article-title":"Intrastromal corneal ring: 12\u2010month sighted myopic eyes","volume":"12","author":"Nose W","year":"1996","journal-title":"J Refract Surg"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(97)30183-3"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(02)01773-6"},{"key":"e_1_2_5_14_2","first-page":"10","article-title":"Queratoplastia refractiva, estudios e informaciones","volume":"2","author":"Barraquer JI","year":"1949","journal-title":"Oftalmol\u00f3gica"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004397-196606010-00004"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1990.01070090047037"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081-597X-19891101-10"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(00)00451-X"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(01)00646-7"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(02)02038-2"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2007.12.022"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2007.06.055"},{"key":"e_1_2_5_23_2","doi-asserted-by":"crossref","first-page":"645","DOI":"10.3928\/1081-597X-20031101-06","article-title":"Ferrara intrastromal corneal ring segments for severe keratoconus","volume":"19","author":"Miranda D","year":"2003","journal-title":"J Refract Surg"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2006.02.044"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0012337"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ico.0000208820.32614.00"},{"key":"e_1_2_5_27_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.04-0558"},{"key":"e_1_2_5_28_2","first-page":"520","article-title":"Characterization of the aspheric corneal surface with intrastromal corneal ring segments","volume":"15","author":"Holmes\u2010Higgin DK","year":"1999","journal-title":"J Refract Surg"},{"key":"e_1_2_5_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)71167-5"},{"key":"e_1_2_5_30_2","doi-asserted-by":"publisher","DOI":"10.4321\/S0365-66912004000800006"},{"key":"e_1_2_5_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2010.08.025"},{"key":"e_1_2_5_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2010.04.028"}],"container-title":["Clinical &amp; Experimental Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1442-9071.2011.02698.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1442-9071.2011.02698.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T23:10:05Z","timestamp":1698707405000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1442-9071.2011.02698.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["10.1111\/j.1442-9071.2011.02698.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1442-9071.2011.02698.x","archive":["Portico"],"relation":{},"ISSN":["1442-6404","1442-9071"],"issn-type":[{"value":"1442-6404","type":"print"},{"value":"1442-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7]]},"assertion":[{"value":"2012-07-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}