{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T10:20:00Z","timestamp":1709806800822},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,3,15]],"date-time":"2012-03-15T00:00:00Z","timestamp":1331769600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:p><jats:bold>Aim:\u2002<\/jats:bold> In this study, the aim was to determine the demographic characteristics of elderly patients with gastroduodenal ulcer who had undergone endoscopic hemostasis by comparing them with younger patients.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> A total of 353 patients with Forrest class I\u2013IIa hemorrhagic gastroduodenal ulcer who underwent endoscopic hemostasis at our hospital between December 2004 and May 2010 were divided into two groups: one for those 75\u2003years or older (old\u2010old group; <jats:italic>n<\/jats:italic>\u2003=\u200371; age \u226575\u2003years) and one for those younger than 75\u2003years (younger group; <jats:italic>n<\/jats:italic>\u2003=\u2003282; age &lt;75\u2003years). Then, their demographic characteristics were compared.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> There were significantly more female patients, patients with underlying chronic renal failure and patients using non\u2010steroidal anti\u2010inflammatory drugs in the old\u2010old group than in the younger group. In addition, the prevalence of open\u2010type atrophy in the background gastric mucosa was significantly higher in the old\u2010old group. Although more than half the patients in each group were infected with <jats:italic>Helicobacter\u2003pylori<\/jats:italic>, the prevalence was significantly higher in the younger group. Of the patients who underwent endoscopic hemostasis only once, those in the old\u2010old group constituted a significantly higher medical cost than those in the younger group. Comparison of deaths between the two groups revealed that the old\u2010old patients were more likely to develop severe complications associated with hematemesis, such as aspiration pneumonia.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> The observed lower prevalence of <jats:italic>Helicobacter pylori<\/jats:italic> infection among the elderly patients compared to the younger patients with hemorrhagic gastroduodenal ulcer suggests that other factors, such as non\u2010steroidal anti\u2010inflammatory drugs use and chronic renal failure, predispose the elderly to hemorrhagic ulcer.<\/jats:p>","DOI":"10.1111\/j.1443-1661.2012.01245.x","type":"journal-article","created":{"date-parts":[[2012,3,16]],"date-time":"2012-03-16T03:50:04Z","timestamp":1331869804000},"page":"319-324","source":"Crossref","is-referenced-by-count":3,"title":["Clinical evaluation of hemorrhagic gastroduodenal ulcer in the elderly: Is <i>Helicobacter\u2003pylori<\/i> infection a risk factor for hemorrhage?"],"prefix":"10.1111","volume":"24","author":[{"given":"Kaoru","family":"Domon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Hirano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takafumi","family":"Otsuka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinori","family":"Fujitsuka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motoi","family":"Takeuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinori","family":"Kikuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeru","family":"Nakano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinori","family":"Igarashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,3,15]]},"reference":[{"key":"e_1_2_6_2_2","volume-title":"Statistical Handbook of Japan 2010","author":"Statistics Bureau, Ministry of Internal Affairs and Communications","year":"2010"},{"key":"e_1_2_6_3_2","first-page":"198","article-title":"Upper GI\u2010bleeding\u2010value and consequences of emergency endscopy and endoscopic treatment","volume":"38","author":"Kohler B","year":"1991","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1098086"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2001.21907"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8553(05)70186-2"},{"key":"e_1_2_6_7_2","first-page":"1064","article-title":"Characteristics and treatment of geriatric ulcer","volume":"5","author":"Mochizuki F","year":"1990","journal-title":"Clin. 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