{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T15:50:30Z","timestamp":1758124230783},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,10,17]],"date-time":"2006-10-17T00:00:00Z","timestamp":1161043200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chinese Journal of Digestive Diseases"],"published-print":{"date-parts":[[2006,11]]},"abstract":"<jats:p><jats:bold>OBJECTIVE:\u2003<\/jats:bold> Endoscopic ultrasound has emerged as the leading modality to assess the T and N stage in gastric cancer. This study aimed to assess the accuracy of TN staging by endoscopic ultrasound in routine clinical practice in Singapore.<\/jats:p><jats:p><jats:bold>METHODS:\u2003<\/jats:bold> Over a period of 7 years, 77 patients (male: 70%; median age 62.8 years) with gastric cancer underwent preoperative staging with endoscopic ultrasound. Fifty\u2010seven patients eventually underwent surgery with tissues available for histopathological staging and comparison.<\/jats:p><jats:p><jats:bold>RESULTS:\u2003<\/jats:bold> The tumor locations were: cardia: 13; corpus: 20; incisura: 19; antrum: 25. The majority was poorly differentiated (57.1%); 26% were moderately differentiated and 16.9% were well differentiated adenocarcinoma. Compared to pathological staging, the overall accuracy of T staging by endoscopic ultrasound was 77.2% (17.5% under\u2010staged: 5.3% over\u2010staged). The staging accuracy of T1 (92.9%) and T3 (81.8%) was higher than T2 (57.1%) and T4. For N staging, the accuracy of endoscopic ultrasound was 59.6% (26.3% under\u2010staged; 14% over\u2010staged); this was significantly superior to computer tomography (43.9%).<\/jats:p><jats:p><jats:bold>CONCLUSION:\u2003<\/jats:bold> Endoscopic ultrasound is useful for the T staging of gastric cancer, with an overall accuracy rate of 77%, and up to 93% for T1 lesions. Under\u2010staging may occur due to microscopic tumor infiltration, while over\u2010staging may arise due to inflammatory reactions. The accuracy of N staging is lower at 60%, but could be further improved with the use of fine needle aspiration.<\/jats:p>","DOI":"10.1111\/j.1443-9573.2006.00270.x","type":"journal-article","created":{"date-parts":[[2006,10,18]],"date-time":"2006-10-18T09:28:02Z","timestamp":1161163682000},"page":"191-196","source":"Crossref","is-referenced-by-count":12,"title":["Accuracy of endoscopic ultrasound staging of gastric cancer in routine clinical practice in Singapore"],"prefix":"10.1111","volume":"7","author":[{"given":"Tiing Leong","family":"ANG","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tay Meng","family":"NG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwong Ming","family":"FOCK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eng 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