{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:47:51Z","timestamp":1782604071997,"version":"3.54.5"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,4,4]],"date-time":"2012-04-04T00:00:00Z","timestamp":1333497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background:\u2002<\/jats:bold> Laparoendoscopic single\u2010site surgery is a revolution in minimally invasive surgery in recent years, and cholecystectomy is the most common intervention. However, laparoendoscopic single\u2010site cholecystectomy (LESSC) is a controversial procedure. Its safety, cosmetic results, complications, post\u2010operative pain and post\u2010operative stay are not confirmed by multi\u2010centre randomized controlled studies.<\/jats:p><jats:p><jats:bold>Objectives:\u2002<\/jats:bold> This review examined the impact of LESSC versus conventional laparoscopic cholecystectomy (CLC). The primary outcomes were conversional rate and intraoperative and post\u2010operative complications, and other outcomes were cosmetic results, operative time, post\u2010operative pain and post\u2010operative stay.<\/jats:p><jats:p><jats:bold>Data sources:\u2002<\/jats:bold> Pubmed, EMbase, Web of Science, Ovid, clinical trials of the US National Institutes of Health and Cochrane Database of Systematic Reviews and Controlled Trials Register were searched to identify all possible randomized controlled trials (RCTs).<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Two reviewers completed article search, and eligible data were entered into a computerized spreadsheet for analysis.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Nine studies were obtained using the search strategy. Patients accepting LESSC had a higher conversion rate than those having CLC (7.17 (3.00, 17.11) (<jats:italic>P<\/jats:italic> &lt; 0.01)). There was no significant difference for total complications between the two groups (1.17 (0.76, 1.80) (<jats:italic>P<\/jats:italic>= 0.46)), but incidence of incisional hernia and haemorrhage (seroma) in the LESSC group was obviously higher than that in the CLC group. Operative time was much longer in the LESSC group (mean difference: 10.69 (3.14, 18.24) (<jats:italic>P<\/jats:italic>= 0.006)). Cosmetic results favoured LESSC; however, post\u2010operative abdominal pain and post\u2010operative stay were not significantly different between the two groups in most of the nine studies.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> LESSC can be safely performed with better cosmetic results; however, it carries a higher conversion rate and a longer operative time, and offers no benefit in terms of post\u2010operative abdominal pain and post\u2010operative stay. Further RCTs, according to the CONSORT statement, are advocated to validate its objective benefits.<\/jats:p>","DOI":"10.1111\/j.1445-2197.2012.06044.x","type":"journal-article","created":{"date-parts":[[2012,4,4]],"date-time":"2012-04-04T07:17:51Z","timestamp":1333523871000},"page":"303-310","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Laparoendoscopic single\u2010site cholecystectomy versus conventional laparoscopic cholecystectomy: a systematic review of randomized controlled trials"],"prefix":"10.1111","volume":"82","author":[{"given":"Dong","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen\u2010Ling","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,4,4]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(91)90603-B"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-004-0471-1"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2005.12.007"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-010-1217-5"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.1997.02586.x"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1159\/000055014"},{"key":"e_1_2_6_8_2","article-title":"Intermediate results of a prospective randomized controlled trial of traditional four\u2010port laparoscopic cholecystectomy versus single\u2010incision laparoscopic cholecystectomy","author":"Phillips MS","year":"2011","journal-title":"Surg. 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