{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T17:28:21Z","timestamp":1776706101934,"version":"3.51.2"},"reference-count":27,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2012,9,3]],"date-time":"2012-09-03T00:00:00Z","timestamp":1346630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Major trauma patients are at significant risk of developing pulmonary embolism (<jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content>). We aimed to (i) analyse the current incidence and timing of <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content> after injury; (ii) identify risk factors that predispose major trauma patients to the occurrence of <jats:styled-content style=\"fixed-case\">PE;<\/jats:styled-content> and (iii) describe the use of vena cava filters (<jats:styled-content style=\"fixed-case\">VCFs<\/jats:styled-content>) following major trauma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Prospectively collected data from <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>he <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>lfred <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ospital's <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>rauma <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>egistry were used to identify all major trauma patients admitted over a 7\u2010year period. A multivariable logistic regression model was used to identify factors associated with the occurrence of <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content>. A similar model was developed to identify factors associated with the use of <jats:styled-content style=\"fixed-case\">VCFs<\/jats:styled-content> inserted at the discretion of the treating clinician.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>\u2002A total of 6344 major trauma patients were treated during this period, with 73.2% male, mean age of 44.2, 90.2% with a blunt mechanism of injury and mean injury severity score of 24.3. Prophylactic <jats:styled-content style=\"fixed-case\">VCFs<\/jats:styled-content> were inserted in 511 patients (8.1%), with a mean time to insertion of 3.6 days after injury. There were 45 <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content>, 2 of which were fatal. The mean time to <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content> was 12 days post\u2010injury. Three variables were independently associated with the occurrence of <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content>: the absence of a <jats:styled-content style=\"fixed-case\">VCF<\/jats:styled-content>; number of injuries to the lower limb; and central venous catheterization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content> rate was 0.71%. Lower limb injuries and central venous catheterization are independently associated with a higher risk of <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content> after major trauma and <jats:styled-content style=\"fixed-case\">VCFs<\/jats:styled-content> are associated with a reduced risk.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1445-2197.2012.06192.x","type":"journal-article","created":{"date-parts":[[2012,9,4]],"date-time":"2012-09-04T00:11:18Z","timestamp":1346717478000},"page":"817-821","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Pulmonary embolism and the use of vena cava filters after major trauma"],"prefix":"10.1111","volume":"82","author":[{"given":"Lachlan M.","family":"Batty","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery The Alfred Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart M.","family":"Lyon","sequence":"additional","affiliation":[{"name":"Department of Radiology The Alfred Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam S.","family":"Dowrick","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery The Alfred Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Bailey","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Preventive Medicine Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick D.","family":"Mahar","sequence":"additional","affiliation":[{"name":"Victorian Adult Burn Service The Alfred Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan M.","family":"Liew","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery The Alfred Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,9,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.suc.2005.10.015"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199412153312401"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ccx.0000144941.09650.9f"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ta.0000197607.23019.ab"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0b013e31817f980f"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1072-7515(99)00137-4"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1067\/msy.2000.108224"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-199701000-00017"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000137138.40116.6c"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-200207000-00032"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-199410000-00013"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200109000-00001"},{"key":"e_1_2_6_14_1","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1177\/000313480507100504","article-title":"Deep venous thrombosis and pulmonary embolism in trauma patients: an overstatement of the problem?","volume":"71","author":"Stawicki SP","year":"2005","journal-title":"Am. 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