{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T12:56:35Z","timestamp":1762865795486},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,1,26]],"date-time":"2012-01-26T00:00:00Z","timestamp":1327536000000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background:\u2002<\/jats:bold> Takotsubo cardiomyopathy (TC) is increasingly recognised in patients presenting with features of acute coronary syndrome. We present a single centre experience of TC with medium term follow up.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Fifty\u2010two consecutive patients presenting with a diagnosis of TC were included. The clinical presentation, complications, baseline and follow\u2010up echocardiograms and cardiac magnetic resonance imaging were analysed.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Fifty\u2010one patients were female. A stressful event preceded presentation in 37 (71%) patients. Chest pain was the most common symptom (83%). Two patients presented with an out\u2010of\u2010hospital cardiac arrest. ST segment elevation (40%) and global T wave inversion (44%) were the most frequent electrocardiogram changes. Left ventricular assessment demonstrated typical apical ballooning in 41 patients and 11 patients demonstrated the mid\u2010wall variant. In\u2010hospital complications occurred in 11 patients (21%) and included acute pulmonary oedema (<jats:italic>n<\/jats:italic>\u2003=\u20032), cardiogenic shock (<jats:italic>n<\/jats:italic>\u2003=\u20035); two of whom had a significant left ventricular outflow gradient, atrial fibrillation (<jats:italic>n<\/jats:italic>\u2003=\u20031), left ventricular thrombus (<jats:italic>n<\/jats:italic>\u2003=\u20032) and a cerebrovascular event (<jats:italic>n<\/jats:italic>\u2003=\u20032). Left ventricular function at presentation and follow up was compared in 40 patients. The mean ejection fraction in this group at presentation was 47% (20\u201370%) compared with that at follow up of 63% (44\u201376%). There were no significant complications or recurrences at follow up.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> While TC is a reversible condition with low rates of complications and recurrence at follow up it is, as demonstrated in our cohort, associated with significant in\u2010hospital morbidity in a proportion of patients.<\/jats:p>","DOI":"10.1111\/j.1445-5994.2011.02474.x","type":"journal-article","created":{"date-parts":[[2011,3,14]],"date-time":"2011-03-14T07:37:43Z","timestamp":1300088263000},"page":"35-42","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Takotsubo cardiomyopathy: an Australian single centre experience with medium term follow up"],"prefix":"10.1111","volume":"42","author":[{"given":"H.","family":"Samardhi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O. 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