{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T22:17:15Z","timestamp":1790201835306,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2012,10,10]],"date-time":"2012-10-10T00:00:00Z","timestamp":1349827200000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Internal Medicine Journal"],"published-print":{"date-parts":[[2012,10]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>N<\/jats:styled-content>orth A<\/jats:styled-content>merican and E<\/jats:styled-content>uropean literature suggest that the incidence rate for pregnancy\u2010related thromboembolism (VTE<\/jats:styled-content>) ranges from 0.5 to 2 per 1000 pregnancies. However, there is a paucity of data regarding pregnancy\u2010related VTE<\/jats:styled-content> in A<\/jats:styled-content>ustralia and N<\/jats:styled-content>ew Z<\/jats:styled-content>ealand.<\/jats:p><\/jats:sec>Aims<\/jats:title>To define the epidemiology, management and adverse effects of pregnancy\u2010related VTE<\/jats:styled-content> in A<\/jats:styled-content>ustralia and N<\/jats:styled-content>ew Z<\/jats:styled-content>ealand.<\/jats:p><\/jats:sec>Method<\/jats:title>Retrospective chart review of pregnant patients with objectively diagnosed pregnancy\u2010related VTE<\/jats:styled-content> at M<\/jats:styled-content>onash M<\/jats:styled-content>edical C<\/jats:styled-content>entre and the N<\/jats:styled-content>orth S<\/jats:styled-content>hore H<\/jats:styled-content>ospital from J<\/jats:styled-content>anuary 2007 to M<\/jats:styled-content>arch 2011.<\/jats:p><\/jats:sec>Results<\/jats:title>Sixty women with VTE<\/jats:styled-content> were identified, 31 and 29 in the antepartum and post\u2010partum period respectively. VTE<\/jats:styled-content> occurred as early as 8 weeks of gestation. There was a trend towards higher proportion of PE<\/jats:styled-content> in the postpartum period. Most antenatal patients were started on enoxaparin and dosed according to weight at diagnosis. A wide variability in maintenance dosing strategies was observed. Three (5%, 95% CI: 1% to 14%) patients suffered major bleeds, all occurring post\u2010partum. Recurrences occurred in two post\u2010partum patients who received a truncated course of enoxaparin for distal deep\u2010vein thrombosis. Although more women had an induction of labour, this did not translate into an increased Caesarean section rate.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The epidemiology of pregnancy\u2010related VTE<\/jats:styled-content> is similar to that of other developed countries. All three bleeding events occurred in the immediate post\u2010partum setting, highlighting the need for caution at this critical time. VTE<\/jats:styled-content> recurrences occurred in those women with post\u2010partum distal deep\u2010vein thrombosis treated with an abbreviated course of enoxaparin.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1445-5994.2012.02863.x","type":"journal-article","created":{"date-parts":[[2012,7,4]],"date-time":"2012-07-04T22:17:14Z","timestamp":1341440234000},"page":"1104-1112","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["How do we manage venous thromboembolism in pregnancy? A retrospective review of the practice of diagnosing and managing pregnancy\u2010related venous thromboembolism at two major hospitals in A<\/scp>ustralia and N<\/scp>ew Z<\/scp>ealand"],"prefix":"10.1111","volume":"42","author":[{"given":"N.","family":"Chan","sequence":"first","affiliation":[{"name":"Department of Clinical Haematology Monash Medical Centre Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Merriman","sequence":"additional","affiliation":[{"name":"Department of Haematology North Shore Hospital WDHB Takapuna Auckland City New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Hyder","sequence":"additional","affiliation":[{"name":"Department of Haematology North Shore Hospital WDHB Takapuna Auckland City New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Woulfe","sequence":"additional","affiliation":[{"name":"Department of Haematology North Shore Hospital WDHB Takapuna Auckland City New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Tran","sequence":"additional","affiliation":[{"name":"Department of Clinical Haematology Monash Medical Centre Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Chunilal","sequence":"additional","affiliation":[{"name":"Department of Clinical Haematology Monash Medical Centre Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,10,10]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1160\/TH08-08-0526","article-title":"Venous thromboembolism in pregnancy: diagnosis, management and prevention","volume":"101","author":"Chunilal SD","year":"2009","journal-title":"Thromb Haemost"},{"key":"e_1_2_11_3_1","first-page":"1","article-title":"Pregnancy\u2010related mortality surveillance \u2013 United States, 1991\u20131999","volume":"52","author":"Chang J","year":"2003","journal-title":"MMWR Surveill Summ"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2010.02847.x"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0761"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2004.02.003"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2005.01204.x"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2009.03678.x"},{"key":"e_1_2_11_9_1","volume-title":"The Australian Version of the International Classification of Diseases, 9th Revision, Clinical Modification (ICD\u20109\u2010CM)","author":"National Coding Centre","year":"1996"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)34240-2"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2001.00004.x"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-143-10-200511150-00006"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2007.06826.x"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.091692"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-199904000-00023"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)75296-X"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)10265-9"},{"key":"e_1_2_11_18_1","unstructured":"Royal College of Obstetricians and Gynaecologists (RCOG) [homepage on the Internet]. London (UK): reducing the risk of thrombosis and embolism during pregnancy and the puerperium. Green\u2010top Guideline No. 37. [updated2009]; [cited 2011 Sep 1]. Available from URL:http:\/\/www.rcog.org.uk\/files\/rcog\u2010corp\/GTG37aReducingRiskThrombosis.pdf"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2010.1.173"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1160\/TH04-08-0506"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0049-3848(09)70136-7"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2009.07786.x"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.162.10.1170"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.03.133"},{"key":"e_1_2_11_25_1","unstructured":"Department of Health [homepage on the Internet]. Melbourne (Australia): Consultative Council on Obstetric and Paediatric Mortality and Morbidity. 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