{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T04:57:51Z","timestamp":1792299471389,"version":"4.4.0"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,9,20]],"date-time":"2006-09-20T00:00:00Z","timestamp":1158710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim:\u2002<\/jats:bold> The study was undertaken to meet the need of the Ministry of Health to have local evidence on the effectiveness of active management of third\u2010stage labor (AMTSL) in reducing the incidence of postpartum hemorrhage (PPH)\u2003\u2265\u2003500\u2003mL and the need for PPH treatment.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Using a quasi\u2010experimental design, AMTSL was introduced for all births attended by government midwives (at home, community, and district levels) in one district while standard practice without AMTSL was continued in three neighboring districts (with a 1:2 ratio of participants). Oxytocin (10\u2003IU) was administered either by standard disposable syringe and needle or by a prefilled, single\u2010use injection device. Postpartum blood loss was estimated using standard containers; other outcome measures included the duration of third stage, the need for additional treatments, and final maternal condition. A total of 3607 women participated (1236 in the intervention district and 2371 in the comparison districts). Multivariate logistic regression was used to control for age, parity, place of delivery, and first\u2010stage oxytocin augmentation.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> AMTSL was associated with reduced risks for prolonged third stage beyond 30\u2003min (odds ratio [OR]\u2003=\u20030.20, 95%; confidence interval [CI]: 0.11, 0.35), supplemental oxytocin (OR\u2003=\u20030.68, 95% CI: 0.49, 0.94), and bimanual compression (OR\u2003=\u20030.63, 95%; CI: 0.41, 0.98). When cases with first\u2010stage oxytocin augmentation were excluded, AMTSL was associated with a 34% reduction in PPH incidence (OR\u2003=\u20030.66, 95%; CI: 0.45, 0.98).<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> This study supports the value of AMTSL in reducing the incidence of PPH, shortening the third stage of labor, and reducing the need for additional treatments.<\/jats:p>","DOI":"10.1111\/j.1447-0756.2006.00436.x","type":"journal-article","created":{"date-parts":[[2006,9,20]],"date-time":"2006-09-20T09:26:20Z","timestamp":1158744380000},"page":"489-496","source":"Crossref","is-referenced-by-count":15,"title":["Reducing postpartum hemorrhage in Vietnam: Assessing the effectiveness of active management of third\u2010stage labor"],"prefix":"10.1111","volume":"32","author":[{"given":"Vivien D.","family":"Tsu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tran T. P.","family":"Mai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yen H.","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huong T. T.","family":"Luu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,9,20]]},"reference":[{"key":"e_1_2_7_2_2","volume-title":"Research on Maternal Mortality in Vietnam, 2000\u20132001.","author":"Ministry of Health of Vietnam.","year":"2004"},{"key":"e_1_2_7_3_2","volume-title":"Findings of the Survey on Maternal Mortality in Lap Thach and Yen Lap Districts, Vinh Phu Province","author":"Do TH","year":"1995"},{"key":"e_1_2_7_4_2","first-page":"CD000007","article-title":"Active versus expectant management in the third stage of labour","volume":"3","author":"Prendiville WJ","year":"2000","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_5_2","volume-title":"Integrated Management of Complications in Pregnancy and Childbirth (IMPAC): a Guide for Midwives and Doctors.","author":"World Health Organization (WHO).","year":"2000"},{"key":"e_1_2_7_6_2","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/S1701-2163(16)30440-6","article-title":"FIGO\/ICM global initiative to prevent post\u2010partum hemorrhage","volume":"26","author":"International Joint Policy Statement.","year":"2004","journal-title":"J Obstet Gynaecol Can"},{"key":"e_1_2_7_7_2","volume-title":"Safe Motherhood Master Plan, 2003\u20132010.","author":"Ministry of Health of Vietnam.","year":"2004"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0001-6349.2005.00579.x"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.331.7519.723"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2005.00711.x"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2005.10.019"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(03)00186-3"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(97)70266-7"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.297.6659.1295"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)09409-9"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.2002.810215.x"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2000.tb13236.x"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0028-2243(92)90069-B"},{"key":"e_1_2_7_19_2","first-page":"CD000494","article-title":"Prostaglandins for prevention of postpartum haemorrhage","volume":"4","author":"Gulmezoglu AM","year":"2001","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)05835-4"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2005.00307.x"},{"key":"e_1_2_7_22_2","volume-title":"Stability of Injectable Oxytocics in Tropical Climates","author":"Hogerzeil HV","year":"1993"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2004.00490.x"},{"key":"e_1_2_7_24_2","first-page":"286","article-title":"International survey on variations in practice of the management of the third stage of labour","volume":"81","author":"Festin MR","year":"2003","journal-title":"Bull World Health Organ"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1447-0756.2006.00436.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1447-0756.2006.00436.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T20:21:41Z","timestamp":1697314901000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/j.1447-0756.2006.00436.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9,20]]},"references-count":23,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2006,10]]}},"alternative-id":["10.1111\/j.1447-0756.2006.00436.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1447-0756.2006.00436.x","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,9,20]]}}}