{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T08:07:15Z","timestamp":1759565235833},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,9,20]],"date-time":"2006-09-20T00:00:00Z","timestamp":1158710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim:\u2002<\/jats:bold> To evaluate the effect of premature rupture of membranes (PROM) at term on the duration of labor and mode of delivery in comparison with intact membranes in nulliparous women with an unfavorable cervix whose labor was induced.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> This retrospective cohort study included all term nulliparous women with an unfavorable cervix requiring labor induction over a 2\u2010year period. Prostaglandin E<jats:sub>2<\/jats:sub> (dinoprostone) and oxytocin were used for labor induction. Criteria for enrolment included (i) singleton pregnancy; (ii) term nulliparous women; or (iii) Bishop score below 6. Statistics were analyzed with Student\u2019s <jats:italic>t<\/jats:italic>\u2010test, \u03c7<jats:sup>2<\/jats:sup>\u2010test, Fisher\u2019s exact test, and multiple logistic regression.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Our study subjects were 82 women whose labor was induced for PROM and 219 women with intact membranes whose labor was induced for social or fetal reasons. The mean durations of active phase of labor were not significantly different between women with PROM and those with intact membranes. However, the women with PROM had a significantly longer mean duration of second stage and a higher rate of cesarean delivery for failure to progress than those with intact membranes. Multiple logistic regression demonstrated that only PROM and fetal macrosomia were significantly associated with an increased risk of cesarean delivery for failure to progress after other confounding variables were adjusted.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> Labor induction for PROM at term in nulliparous women with an unfavorable cervix is associated with longer duration of the second stage and a higher risk of cesarean delivery for failure to progress in comparison to those with intact membranes.<\/jats:p>","DOI":"10.1111\/j.1447-0756.2006.00443.x","type":"journal-article","created":{"date-parts":[[2006,9,20]],"date-time":"2006-09-20T09:26:20Z","timestamp":1158744380000},"page":"482-488","source":"Crossref","is-referenced-by-count":16,"title":["Comparative study of induction of labor in nulliparous women with premature rupture of membranes at term compared to those with intact membranes: Duration of labor and mode of delivery"],"prefix":"10.1111","volume":"32","author":[{"given":"Kyo Hoon","family":"Park","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joon\u2010Seok","family":"Hong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Kyung","family":"Ko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong Kyoon","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chul Min","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hoon","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bok Rin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,9,20]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(70)90378-9"},{"key":"e_1_2_5_3_2","first-page":"76","article-title":"A retrospective review of the efficacy and safety of prostaglandin E2 with premature rupture of the membranes at term","volume":"80","author":"Meikle SF","year":"1992","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_4_2","first-page":"671","article-title":"Premature rupture of membranes at term in nulliparous women: A hazard?","volume":"76","author":"Cammu H","year":"1990","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_5_2","first-page":"547","article-title":"Premature rupture of the membranes and prolonged latency","volume":"57","author":"Johnson JW","year":"1981","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199604183341601"},{"key":"e_1_2_5_7_2","first-page":"22","article-title":"Fetal hazard after rupture of the membranes. A report from the collaborative project","volume":"28","author":"Shubeck F","year":"1966","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_8_2","volume-title":"Modern Perinatal Medicine","author":"Schwarz R","year":"1974"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004040000071"},{"key":"e_1_2_5_10_2","first-page":"697","article-title":"Management of premature rupture of membranes and unfavorable cervix in term pregnancy","volume":"63","author":"Duff P","year":"1984","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(84)90388-0"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/145.1.1"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.2002.810306.x"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(02)00007-3"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(92)91845-2"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(98)70056-0"},{"key":"e_1_2_5_17_2","first-page":"501","volume-title":"Obstetric and Perinatal Infection","author":"Friedman EA","year":"1973"},{"key":"e_1_2_5_18_2","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0002-9378(16)32231-1","article-title":"The course of labor in term patients with chorioamnionitis","volume":"147","author":"Duff P","year":"1983","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_5_19_2","first-page":"42","article-title":"The spontaneous motility of human myometrial strips in vitro and its modification by some bacterial extracts","volume":"324","author":"Leek BF","year":"1982","journal-title":"J Physiol"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.107.3_Supplement.105S"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-829865"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.166"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(97)00259-7"},{"key":"e_1_2_5_24_2","first-page":"721","article-title":"Use of ampicillin and corticosteroids in premature rupture of membranes: A randomized study","volume":"73","author":"Morales WJ","year":"1989","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-199312000-00004"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-199912000-00005"},{"key":"e_1_2_5_27_2","doi-asserted-by":"publisher","DOI":"10.1159\/000088424"},{"key":"e_1_2_5_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1982.tb04631.x"},{"key":"e_1_2_5_29_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1980.tb04466.x"},{"key":"e_1_2_5_30_2","first-page":"93","article-title":"A comparison of early and delayed induction of labor with spontaneous rupture of membranes at term","volume":"74","author":"Wagner MV","year":"1989","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_31_2","first-page":"758","article-title":"Active\u2010phase arrest in labor: Predictors of cesarean delivery in a nulliparous population","volume":"81","author":"Handa VL","year":"1993","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_32_2","first-page":"913","article-title":"Chorioamnionitis: A harbinger of dystocia","volume":"79","author":"Satin AJ","year":"1992","journal-title":"Obstet Gynecol"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1447-0756.2006.00443.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1447-0756.2006.00443.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T20:20:59Z","timestamp":1697314859000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/j.1447-0756.2006.00443.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9,20]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2006,10]]}},"alternative-id":["10.1111\/j.1447-0756.2006.00443.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1447-0756.2006.00443.x","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,9,20]]}}}