{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T11:22:23Z","timestamp":1778498543300,"version":"3.51.4"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,7,6]],"date-time":"2012-07-06T00:00:00Z","timestamp":1341532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Vulvar cancer is a rare malignancy; most tumors are squamous cell type while adenocarcinomas are rare. Primary adenocarcinomas of the vulva predominantly include extramammary Paget's disease and sweat gland carcinomas. Greene first described a rare form of adenocarcinoma in 1936, which was called adenocarcinoma of mammary\u2010like glands of the vulva because of its morphologic and immunohistochemical resemblance to breast adenocarcinomas. In the management of this entity, varying combinations of surgery, radiation therapy, systemic chemotherapy and\/or hormonal therapy may be used, as in patients with orthotopic breast carcinoma. However, hormonal therapy leads the way in patients with positive hormonal receptors, where other therapies cannot be used due to comorbidities or advanced age. We present the first reported case of an elderly patient with metastatic vulvar adenocarcinoma arising from mammary\u2010like glands, successfully treated with a combination of surgery and hormonal therapy.<\/jats:p>","DOI":"10.1111\/j.1447-0756.2012.01937.x","type":"journal-article","created":{"date-parts":[[2012,7,6]],"date-time":"2012-07-06T07:05:48Z","timestamp":1341558348000},"page":"450-454","source":"Crossref","is-referenced-by-count":16,"title":["Metastatic adenocarcinoma of mammary\u2010like glands of the vulva successfully treated with surgery and hormonal therapy"],"prefix":"10.1111","volume":"39","author":[{"given":"Virginia","family":"Benito","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Arribas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norberto","family":"Medina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amina","family":"Lubrano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Octavio","family":"Arencibia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,7,6]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2011.06.007"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(36)90467-2"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199113060-00006"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004347-199404000-00009"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2006.00237.x"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2007.00817.x"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.dad.0000171601.25315.2b"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/LGT.0b013e31823b3bc6"},{"key":"e_1_2_5_10_2","first-page":"855","article-title":"Primary breast cancer of the vulva: A case report and review of the literature","volume":"112","author":"Gorisek B","year":"2000","journal-title":"Wien Klin Wochenschr"},{"key":"e_1_2_5_11_2","first-page":"4805","article-title":"Ectopic lobular breast cancer of the vulva","volume":"20","author":"Neumann I","year":"2000","journal-title":"Anticancer Res"},{"key":"e_1_2_5_12_2","first-page":"21","article-title":"Primary breast carcinoma of the vulva: Case report and review of literature","volume":"23","author":"Piura B","year":"2002","journal-title":"Eur J Gynaecol Oncol"},{"key":"e_1_2_5_13_2","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.5858\/2002-126-1216-MAOEBT","article-title":"Mucinous adenocarcinoma of ectopic breast tissue of the vulva","volume":"126","author":"Chung\u2010Park M","year":"2002","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4741.2003.09213.x"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1048-891X.2004.14544.x"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2005.15328.x"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2006.00364.x"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1447-0756.2012.01937.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1447-0756.2012.01937.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T01:57:06Z","timestamp":1697335026000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/j.1447-0756.2012.01937.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,6]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["10.1111\/j.1447-0756.2012.01937.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1447-0756.2012.01937.x","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,6]]}}}