{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T22:25:55Z","timestamp":1784759155777,"version":"3.55.0"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,10,29]],"date-time":"2012-10-29T00:00:00Z","timestamp":1351468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Obstet and Gynaecol"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>wing sarcomas\/peripheral primitive neuroectodermal tumors (<jats:styled-content style=\"fixed-case\">ES<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">pPNET<\/jats:styled-content>) are extremely rare in the vulva. A review of the literature reveals only 14 previously reported possible cases. Here we reported a case of primary <jats:styled-content style=\"fixed-case\">e<\/jats:styled-content>xtraskeletal <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>wing's <jats:styled-content style=\"fixed-case\">s<\/jats:styled-content>arcoma (<jats:styled-content style=\"fixed-case\">EES<\/jats:styled-content>) of the vulva in a 37\u2010year\u2010old woman. Characteristic histologic features of <jats:styled-content style=\"fixed-case\">ES<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">pPNET<\/jats:styled-content> were present in this case, including a monomorphic population of small round blue cells with cytoplasmic glycogen confirmed by periodic acid\u2010<jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>chiff, membrane staining with <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>99 and nuclear staining with <jats:styled-content style=\"fixed-case\">FLI<\/jats:styled-content>\u20101. After surgery, the patient was found to have pulmonary metastasis and then received six cycles of polychemotherapy. She is still alive with stable disease after 1 year of follow up. Our findings underline the crucial role of immunohistochemical techniques in the differential diagnosis of small round cell tumors in these unusual locations. We also give a summary about the clinical and pathological features of the primary <jats:styled-content style=\"fixed-case\">ES<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">pPNET<\/jats:styled-content> in the vulva reported previously in the literature.<\/jats:p>","DOI":"10.1111\/j.1447-0756.2012.02019.x","type":"journal-article","created":{"date-parts":[[2012,10,30]],"date-time":"2012-10-30T02:22:04Z","timestamp":1351563724000},"page":"746-749","source":"Crossref","is-referenced-by-count":11,"title":["Primary <scp>E<\/scp>wing's sarcoma of vulva: A case report and a review of the literature"],"prefix":"10.1111","volume":"39","author":[{"given":"Shao\u2010Min","family":"Che","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology Xi'an Jiaotong University School of Medicine  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei\u2010Long","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Pathology First Affiliated Hospital Xi'an Jiaotong University School of Medicine  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong\u2010Wei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Xi'an Jiaotong University School of Medicine  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Xi'an Jiaotong University School of Medicine  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Du","family":"Meng","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Xi'an Jiaotong University School of Medicine  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,10,29]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004347-200004000-00002"},{"key":"e_1_2_7_3_1","first-page":"158","article-title":"A rare lesion of the vulva","volume":"40","author":"Habib K","year":"1992","journal-title":"Arch Anat Cytol Pathol"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1994.1204"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004347-199501000-00010"},{"key":"e_1_2_7_6_1","first-page":"161","article-title":"A peripheral neuroectodermal tumor of the vulva","volume":"8","author":"Paredes E","year":"1995","journal-title":"Acta Med Port"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000328353"},{"key":"e_1_2_7_8_1","first-page":"263","article-title":"Primary uterine and vulvar Ewing's sarcoma\/peripheral neuroectodermal tumors in children: Two unusual locations","volume":"21","author":"Lazure T","year":"2001","journal-title":"Ann Pathol"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2005.00330.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2006.040931"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2008.01.013"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2009.07.006"},{"key":"e_1_2_7_13_1","first-page":"117","article-title":"Peripheral primitive neuroectodermal tumor (PNET) of the vulva: A case report","volume":"32","author":"Halil S","year":"2011","journal-title":"Eur J Gynaecol Oncol"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200008010-00022"},{"key":"e_1_2_7_15_1","first-page":"231","article-title":"CD99\/p30\/32\/MIC2\/neuroectodermal\/Ewing's sarcoma antigen as an immunohistochemical marker: Review of more than 600 tumors and the literature experience","volume":"2","author":"Stevenson A","year":"1994","journal-title":"Appl Immunohistochem"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200012000-00010"}],"container-title":["Journal of Obstetrics and Gynaecology Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1447-0756.2012.02019.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1447-0756.2012.02019.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1447-0756.2012.02019.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/j.1447-0756.2012.02019.x","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1447-0756.2012.02019.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T01:10:39Z","timestamp":1694135439000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/j.1447-0756.2012.02019.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,29]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["10.1111\/j.1447-0756.2012.02019.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1447-0756.2012.02019.x","archive":["Portico"],"relation":{},"ISSN":["1341-8076","1447-0756"],"issn-type":[{"value":"1341-8076","type":"print"},{"value":"1447-0756","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,29]]}}}