{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:19:09Z","timestamp":1792099149392,"version":"4.4.0"},"reference-count":106,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":1584,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,5]]},"DOI":"10.1111\/j.1460-9568.2011.07676.x","type":"journal-article","created":{"date-parts":[[2011,5,3]],"date-time":"2011-05-03T06:53:15Z","timestamp":1304405595000},"page":"1799-1811","source":"Crossref","is-referenced-by-count":67,"title":["Voluntary exercise induces adult hippocampal neurogenesis and BDNF expression in a rodent model of fetal alcohol spectrum disorders"],"prefix":"10.1111","volume":"33","author":[{"given":"Fanny","family":"Boehme","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joana","family":"Gil-Mohapel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"Cox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Patten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica","family":"Giles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia S.","family":"Brocardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian R.","family":"Christie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,5,3]]},"reference":[{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB1|cit1","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.2174\/138161206776389886","article-title":"Fetal alcohol syndrome: a cautionary note","volume":"12","author":"Abel","year":"2006","journal-title":"Curr. Pharm. Des."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB2|cit2","doi-asserted-by":"crossref","first-page":"2896","DOI":"10.1523\/JNEUROSCI.20-08-02896.2000","article-title":"Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus","volume":"20","author":"Aberg","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB3|cit3","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1016\/j.neuroscience.2003.12.039","article-title":"Voluntary exercise protects against stress-induced decreases in brain-derived neurotrophic factor protein expression","volume":"124","author":"Adlard","year":"2004","journal-title":"Neuroscience"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB4|cit4","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.neurobiolaging.2004.05.006","article-title":"The exercise-induced expression of BDNF within the hippocampus varies across life-span","volume":"26","author":"Adlard","year":"2005","journal-title":"Neurobiol. Aging"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB5|cit5","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/S0022-3565(24)37227-1","article-title":"Prenatal ethanol exposure alters the modulation of the gamma-aminobutyric acidA1 receptor-gated chloride ion channel in adult rat offspring","volume":"284","author":"Allan","year":"1998","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB6|cit6","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1002\/cne.901240303","article-title":"Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats","volume":"124","author":"Altman","year":"1965","journal-title":"J. Comp. Neurol."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB7|cit7","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1111\/j.1460-9568.2004.03486.x","article-title":"Dopaminergic nigrostriatal projections regulate neural precursor proliferation in the adult mouse subventricular zone","volume":"20","author":"Baker","year":"2004","journal-title":"Eur. J. Neurosci."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB8|cit8","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1016\/j.neuropharm.2008.07.030","article-title":"Long-term alterations in vulnerability to addiction to drugs of abuse and in brain gene expression after early life ethanol exposure","volume":"55","author":"Barbier","year":"2008","journal-title":"Neuropharmacology"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB9|cit9","doi-asserted-by":"crossref","first-page":"5149","DOI":"10.1523\/JNEUROSCI.23-12-05149.2003","article-title":"Endogenously produced neurotrophins regulate survival and differentiation of cortical progenitors via distinct signaling pathways","volume":"23","author":"Barnabe-Heider","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB10|cit10","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/0165-3806(81)90071-7","article-title":"Prenatal ethanol exposure permanently reduces the number of pyramidal neurons in rat hippocampus","volume":"227","author":"Barnes","year":"1981","journal-title":"Brain Res."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB11|cit11","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0006-8993(77)90310-9","article-title":"The effect of ethanol chronically administered to preweanling rats on cerebellar development: a morphological study","volume":"119","author":"Bauer-Moffett","year":"1977","journal-title":"Brain Res."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB12|cit12","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.neuroscience.2010.02.050","article-title":"Exercise and time-dependent benefits to learning and memory","volume":"167","author":"Berchtold","year":"2010","journal-title":"Neuroscience"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB13|cit13","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/tera.1420440203","article-title":"Permanent neuronal deficits in rats exposed to alcohol during the brain growth spurt","volume":"44","author":"Bonthius","year":"1991","journal-title":"Teratology"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB14|cit14","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1002\/(SICI)1521-1878(199904)21:4<313::AID-BIES7>3.0.CO;2-C","article-title":"Deconstructing cell determination: proneural genes and neuronal identity","volume":"21","author":"Brunet","year":"1999","journal-title":"Bioessays"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB15|cit15","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.pbb.2008.05.004","article-title":"Fetal alcohol spectrum disorder-associated depression: evidence for reductions in the levels of brain-derived neurotrophic factor in a mouse model","volume":"90","author":"Caldwell","year":"2008","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB16|cit16","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1002\/cne.1040","article-title":"Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus","volume":"435","author":"Cameron","year":"2001","journal-title":"J. Comp. Neurol."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB17|cit17","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1097\/01.alc.0000187037.02670.59","article-title":"Moderate fetal alcohol exposure impairs the neurogenic response to an enriched environment in adult mice","volume":"29","author":"Choi","year":"2005","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB18|cit18","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/1750-1326-4-52","article-title":"Regulation of hippocampal progenitor cell survival, proliferation and dendritic development by BDNF","volume":"4","author":"Choi","year":"2009","journal-title":"Mol. Neurodegener."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB19|cit19","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1111\/j.1460-9568.2005.04004.x","article-title":"Voluntary exercise rescues deficits in spatial memory and long-term potentiation in prenatal ethanol-exposed male rats","volume":"21","author":"Christie","year":"2005","journal-title":"Eur. J. Neurosci."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB20|cit20","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1097\/WNR.0b013e3283303794","article-title":"LTD induction suppresses LTP-induced hippocampal adult neurogenesis","volume":"20","author":"Chun","year":"2009","journal-title":"Neuroreport"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB21|cit21","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/0892-0362(91)90084-A","article-title":"Effects of prenatal alcohol exposure at school age. I. Physical and cognitive development","volume":"13","author":"Coles","year":"1991","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB22|cit22","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.nbd.2008.11.004","article-title":"Brain-derived neurotrophic factor (BDNF) overexpression in the forebrain results in learning and memory impairments","volume":"33","author":"Cunha","year":"2009","journal-title":"Neurobiol. Dis."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB23|cit23","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.pharmthera.2008.01.003","article-title":"Ethanol-BDNF interactions: still more questions than answers","volume":"118","author":"Davis","year":"2008","journal-title":"Pharmacol. Ther."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB24|cit24","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1016\/S0893-133X(01)00358-X","article-title":"Regulation of adult neurogenesis by antidepressant treatment","volume":"25","author":"Duman","year":"2001","journal-title":"Neuropsychopharmacology"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB25|cit25","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1002\/cne.20493","article-title":"Voluntary exercise alters the cytoarchitecture of the adult dentate gyrus by increasing cellular proliferation, dendritic complexity, and spine density","volume":"486","author":"Eadie","year":"2005","journal-title":"J. Comp. Neurol."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB26|cit26","doi-asserted-by":"crossref","first-page":"7579","DOI":"10.1073\/pnas.120552597","article-title":"Opiates inhibit neurogenesis in the adult rat hippocampus","volume":"97","author":"Eisch","year":"2000","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB27|cit27","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.neuroscience.2003.09.029","article-title":"Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo","volume":"124","author":"Farmer","year":"2004","journal-title":"Neuroscience"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB28|cit28","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.brainres.2005.02.017","article-title":"Effects of prenatal alcohol exposure on brain-derived neurotrophic factor and its receptor tyrosine kinase B in offspring","volume":"1042","author":"Feng","year":"2005","journal-title":"Brain Res."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB29|cit29","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.neuro.2008.11.009","article-title":"Early exposure to ethanol but not red wine at the same alcohol concentration induces behavioral and brain neurotrophin alterations in young and adult mice","volume":"30","author":"Fiore","year":"2009","journal-title":"Neurotoxicology"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB30|cit30","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1111\/j.1471-4159.2005.03294.x","article-title":"Alcohol is a potent stimulant of immature neuronal networks: implications for fetal alcohol spectrum disorder","volume":"94","author":"Galindo","year":"2005","journal-title":"J. Neurochem."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB31|cit31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.tins.2006.11.001","article-title":"GABA sets the tempo for activity-dependent adult neurogenesis","volume":"30","author":"Ge","year":"2007","journal-title":"Trends Neurosci."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB32|cit32","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.brainresrev.2010.04.011","article-title":"Hippocampal cell loss and neurogenesis after fetal alcohol exposure: insights from different rodent models","volume":"64","author":"Gil-Mohapel","year":"2010","journal-title":"Brain Res. Rev."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB33|cit33","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.brainres.2011.01.116","article-title":"Altered adult hippocampal neuronal maturation in a rat model of fetal alcohol syndrome","volume":"1384","author":"Gil-Mohapel","year":"2011","journal-title":"Brain Res."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB34|cit34","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1177\/15353702-0323006-07","article-title":"Alcohol teratogenesis: mechanisms of damage and strategies for intervention","volume":"230","author":"Goodlett","year":"2005","journal-title":"Exp. Biol. Med. (Maywood)"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB35|cit35","doi-asserted-by":"crossref","first-page":"3168","DOI":"10.1073\/pnas.95.6.3168","article-title":"Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress","volume":"95","author":"Gould","year":"1998","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB36|cit36","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1038\/6365","article-title":"Learning enhances adult neurogenesis in the hippocampal formation","volume":"2","author":"Gould","year":"1999","journal-title":"Nat. Neurosci."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB37|cit37","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0165-3806(00)00032-8","article-title":"Ethanol-induced alterations in the expression of neurotrophic factors in the developing rat central nervous system","volume":"121","author":"Heaton","year":"2000","journal-title":"Brain Res. Dev. Brain Res."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB38|cit38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2009.07.090","article-title":"The effects of exercise on adolescent hippocampal neurogenesis in a rat model of binge alcohol exposure during the brain growth spurt","volume":"1294","author":"Helfer","year":"2009","journal-title":"Brain Res."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB39|cit39","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1196\/annals.1418.016","article-title":"Prenatal alcohol exposure increases vulnerability to stress and anxiety-like disorders in adulthood","volume":"1144","author":"Hellemans","year":"2008","journal-title":"Ann. NY Acad. Sci."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB40|cit40","first-page":"585","article-title":"The fetal alcohol syndrome: a multihandicapped child","volume":"10","author":"Hill","year":"1989","journal-title":"Neurotoxicology"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB41|cit41","doi-asserted-by":"crossref","first-page":"485","DOI":"10.15288\/qjsa.1972.33.485","article-title":"Placental transfer and tissue distribution of ethanol-1- 14 C. A radioautographic study in monkeys and hamsters","volume":"33","author":"Ho","year":"1972","journal-title":"Q. J. Stud. Alcohol"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB42|cit42","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.nbd.2007.02.011","article-title":"Single alcohol exposure in early life damages hippocampal stem\/progenitor cells and reduces adult neurogenesis","volume":"26","author":"Ieraci","year":"2007","journal-title":"Neurobiol. Dis."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB43|cit43","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1023\/A:1015013609424","article-title":"Proliferation and death of cultured fetal neocortical neurons: effects of ethanol on the dynamics of cell growth","volume":"30","author":"Jacobs","year":"2001","journal-title":"J. Neurocytol."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB44|cit44","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/S0006-8993(03)03039-7","article-title":"Exercise-induced changes in hippocampal brain-derived neurotrophic factor and neurotrophin-3: effects of rat strain","volume":"983","author":"Johnson","year":"2003","journal-title":"Brain Res."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB45|cit45","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/978-1-59745-242-7_8","article-title":"Intragastric intubation of alcohol during the perinatal period","volume":"447","author":"Kelly","year":"2008","journal-title":"Methods Mol. Biol."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB46|cit46","doi-asserted-by":"crossref","first-page":"10409","DOI":"10.1073\/pnas.94.19.10409","article-title":"Genetic influence on neurogenesis in the dentate gyrus of adult mice","volume":"94","author":"Kempermann","year":"1997a","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB47|cit47","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1038\/386493a0","article-title":"More hippocampal neurons in adult mice living in an enriched environment","volume":"386","author":"Kempermann","year":"1997b","journal-title":"Nature"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB48|cit48","doi-asserted-by":"crossref","first-page":"75","DOI":"10.2190\/HX7L-4B40-PQNY-2A4P","article-title":"The effect of exercise on hippocampal integrity: review of recent research","volume":"35","author":"Kiraly","year":"2005","journal-title":"Int. J. Psychiatry Med."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB49|cit49","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1111\/j.1530-0277.2007.00528.x","article-title":"Persistent impairment of hippocampal neurogenesis in young adult rats following early postnatal alcohol exposure","volume":"31","author":"Klintsova","year":"2007","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB50|cit50","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/cne.10945","article-title":"Subpopulations of proliferating cells of the adult hippocampus respond differently to physiologic neurogenic stimuli","volume":"467","author":"Kronenberg","year":"2003","journal-title":"J. Comp. Neurol."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB51|cit51","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1523\/JNEUROSCI.16-06-02027.1996","article-title":"Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation","volume":"16","author":"Kuhn","year":"1996","journal-title":"J. Neurosci."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB52|cit52","first-page":"63","article-title":"Effect of pre- and postnatal alcohol consumption on GABA levels of various brain regions in the rat offspring","volume":"23","author":"Ledig","year":"1988","journal-title":"Alcohol Alcohol."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB53|cit53","doi-asserted-by":"crossref","first-page":"239","DOI":"10.5483\/BMBRep.2009.42.5.239","article-title":"Adult hippocampal neurogenesis and related neurotrophic factors","volume":"42","author":"Lee","year":"2009","journal-title":"BMB Rep."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB54|cit54","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1046\/j.1471-4159.2002.01085.x","article-title":"Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice","volume":"82","author":"Lee","year":"2002","journal-title":"J. Neurochem."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB55|cit55","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0301-0082(03)00019-4","article-title":"Neurotrophin secretion: current facts and future prospects","volume":"69","author":"Lessmann","year":"2003","journal-title":"Prog. Neurobiol."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB56|cit56","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0006-8993(97)00762-2","article-title":"Basic fibroblast growth factor- and platelet-derived growth factor-mediated cell proliferation in B104 neuroblastoma cells: effect of ethanol on cell cycle kinetics","volume":"770","author":"Luo","year":"1997","journal-title":"Brain Res."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB57|cit57","doi-asserted-by":"crossref","first-page":"9104","DOI":"10.1523\/JNEUROSCI.20-24-09104.2000","article-title":"Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus","volume":"20","author":"Malberg","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB58|cit58","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.neubiorev.2006.08.003","article-title":"Fetal alcohol spectrum disorders (FASD): from experimental biology to the search for treatment","volume":"31","author":"Mancinelli","year":"2007","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB59|cit59","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0014-2999(00)00904-3","article-title":"Antidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitro","volume":"411","author":"Manev","year":"2001","journal-title":"Eur. J. Pharmacol."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB60|cit60","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1002\/ddrr.68","article-title":"Prevalence and epidemiologic characteristics of FASD from various research methods with an emphasis on recent in-school studies","volume":"15","author":"May","year":"2009","journal-title":"Dev. Disabil. Res. Rev."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB61|cit61","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0741-8329(94)90010-8","article-title":"Hyperactivity in preweanling rats following postnatal alcohol exposure","volume":"11","author":"Melcer","year":"1994","journal-title":"Alcohol"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB62|cit62","doi-asserted-by":"crossref","first-page":"484","DOI":"10.55782\/ane-2008-1714","article-title":"Early postnatal ethanol exposure induces fluctuation in the expression of BDNF mRNA in the developing rat hippocampus","volume":"68","author":"Miki","year":"2008","journal-title":"Acta Neurobiol. Exp. (Wars)"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB63|cit63","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/0006-8993(88)90055-8","article-title":"Use of bromodeoxyuridine-immunohistochemistry to examine the proliferation, migration and time of origin of cells in the central nervous system","volume":"457","author":"Miller","year":"1988","journal-title":"Brain Res."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB64|cit64","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/j.1530-0277.1991.tb01861.x","article-title":"Effect of prenatal exposure to ethanol on the cell cycle kinetics and growth fraction in the proliferative zones of fetal rat cerebral cortex","volume":"15","author":"Miller","year":"1991","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB65|cit65","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1101\/gad.13.13.1647","article-title":"NeuroD is required for differentiation of the granule cells in the cerebellum and hippocampus","volume":"13","author":"Miyata","year":"1999","journal-title":"Genes Dev."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB66|cit66","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1067\/mpd.2001.115313","article-title":"The subtle facial signs of prenatal exposure to alcohol: an anthropometric approach","volume":"139","author":"Moore","year":"2001","journal-title":"J. Pediatr."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB67|cit67","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1002\/neu.20010","article-title":"Ethanol exposure alters neurotrophin receptor expression in the rat central nervous system: effects of neonatal exposure","volume":"60","author":"Moore","year":"2004","journal-title":"J. Neurobiol."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB68|cit68","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.bbr.2010.03.028","article-title":"Regular voluntary exercise cures stress-induced impairment of cognitive function and cell proliferation accompanied by increases in cerebral IGF-1 and GST activity in mice","volume":"211","author":"Nakajima","year":"2010","journal-title":"Behav. Brain Res."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB69|cit69","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.bandc.2007.02.009","article-title":"Fetal alcohol syndrome and the developing socio-emotional brain","volume":"65","author":"Niccols","year":"2007","journal-title":"Brain Cogn."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB70|cit70","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1046\/j.1471-4159.2002.01214.x","article-title":"Binge ethanol exposure decreases neurogenesis in adult rat hippocampus","volume":"83","author":"Nixon","year":"2002","journal-title":"J. Neurochem."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB71|cit71","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0143-4179(90)90146-P","article-title":"Effects of chronic stress on in vivo pituitary-adrenocortical responses to corticotropin releasing hormone","volume":"15","author":"Odio","year":"1990","journal-title":"Neuropeptides"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB72|cit72","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1002\/hipo.20157","article-title":"Environmental enrichment and voluntary exercise massively increase neurogenesis in the adult hippocampus via dissociable pathways","volume":"16","author":"Olson","year":"2006","journal-title":"Hippocampus"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB73|cit73","volume-title":"The Rat Brain in Sterotaxic Cordinates","author":"Paxinos","year":"1982"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB74|cit74","doi-asserted-by":"crossref","first-page":"5638","DOI":"10.1073\/pnas.0611721104","article-title":"An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus","volume":"104","author":"Pereira","year":"2007","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB75|cit75","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0736-5748(92)90059-9","article-title":"Effects of combined pre- and postnatal ethanol exposure (three trimester equivalency) on glial cell development in rat optic nerve","volume":"10","author":"Phillips","year":"1992","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB76|cit76","doi-asserted-by":"crossref","first-page":"13427","DOI":"10.1073\/pnas.96.23.13427","article-title":"Running enhances neurogenesis, learning, and long-term potentiation in mice","volume":"96","author":"van Praag","year":"1999a","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB77|cit77","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/6368","article-title":"Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus","volume":"2","author":"van Praag","year":"1999b","journal-title":"Nat. Neurosci."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB78|cit78","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1042\/bj1030623","article-title":"Developmental changes in alcohol-dehydrogenase activity in rat and guinea-pig liver","volume":"103","author":"Raiha","year":"1967","journal-title":"Biochem. J."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB79|cit79","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1113\/expphysiol.2009.048512","article-title":"Evidence for a release of BDNF from the brain during exercise","volume":"94","author":"Rasmussen","year":"2009","journal-title":"Exp. Physiol."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB80|cit80","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1016\/j.neuroscience.2005.10.050","article-title":"Exercise-induced changes in dendritic structure and complexity in the adult hippocampal dentate gyrus","volume":"137","author":"Redila","year":"2006","journal-title":"Neuroscience"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB81|cit81","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1002\/hipo.20164","article-title":"Hippocampal cell proliferation is reduced following prenatal ethanol exposure but can be rescued with voluntary exercise","volume":"16","author":"Redila","year":"2006","journal-title":"Hippocampus"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB82|cit82","doi-asserted-by":"crossref","first-page":"2505","DOI":"10.1210\/endo-117-6-2505","article-title":"Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation","volume":"117","author":"Reul","year":"1985","journal-title":"Endocrinology"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB83|cit83","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0022-3565(25)21776-1","article-title":"Effect of ethanol on the hypothalamic-pituitary-adrenal axis in the rat: role of corticotropin-releasing factor (CRF)","volume":"229","author":"Rivier","year":"1984","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB84|cit84","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1002\/tera.1420500210","article-title":"Unusual craniofacial dysmorphia due to prenatal alcohol and cocaine exposure","volume":"50","author":"Robin","year":"1994","journal-title":"Teratology"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB85|cit85","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1523\/JNEUROSCI.3741-04.2005","article-title":"Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus","volume":"25","author":"Sairanen","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB86|cit86","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1002\/(SICI)1097-4652(200003)182:3<311::AID-JCP1>3.0.CO;2-9","article-title":"The Ki-67 protein: from the known and the unknown","volume":"182","author":"Scholzen","year":"2000","journal-title":"J. Cell. Physiol."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB87|cit87","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/alcalc\/agn109","article-title":"In vitro neurogenesis from neural progenitor cells isolated from the hippocampus region of the brain of adult rats exposed to ethanol during early development through their alcohol-drinking mothers","volume":"44","author":"Singh","year":"2009","journal-title":"Alcohol Alcohol."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB88|cit88","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1038\/nn1668","article-title":"Social isolation delays the positive effects of running on adult neurogenesis","volume":"9","author":"Stranahan","year":"2006","journal-title":"Nat. Neurosci."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB89|cit89","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1111\/j.1749-6632.1989.tb21013.x","article-title":"Neurobehavioral dose-response effects of prenatal alcohol exposure in humans from infancy to adulthood","volume":"562","author":"Streissguth","year":"1989","journal-title":"Ann. NY Acad. Sci."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB90|cit90","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S0031-9384(00)00351-6","article-title":"Prenatal stress in rats: effects on plasma corticosterone, hippocampal glucocorticoid receptors, and maze performance","volume":"71","author":"Szuran","year":"2000","journal-title":"Physiol. Behav."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB91|cit91","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0736-5748(98)00020-3","article-title":"Prenatal stress: consequences of glucocorticoids on hippocampal development and function","volume":"16","author":"Takahashi","year":"1998","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB92|cit92","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/S0306-4530(98)00024-9","article-title":"Prolonged stress-induced elevation in plasma corticosterone during pregnancy in the rat: implications for prenatal stress studies","volume":"23","author":"Takahashi","year":"1998","journal-title":"Psychoneuroendocrinology"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB93|cit93","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1037\/a0013271","article-title":"Voluntary exercise influences behavioral development in rats exposed to alcohol during the neonatal brain growth spurt","volume":"122","author":"Thomas","year":"2008","journal-title":"Behav. Neurosci."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB94|cit94","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1002\/hipo.20407","article-title":"Long-term depression in vivo: effects of sex, stress, diet, and prenatal ethanol exposure","volume":"18","author":"Titterness","year":"2008","journal-title":"Hippocampus"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB95|cit95","doi-asserted-by":"crossref","DOI":"10.1002\/hipo.20849","article-title":"Prenatal ethanol exposure enhances NMDAR-dependent long-term potentiation in the adolescent female dentate gyrus","author":"Titterness","year":"2010","journal-title":"Hippocampus"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB96|cit96","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/j.neuron.2005.08.023","article-title":"GABAergic excitation promotes neuronal differentiation in adult hippocampal progenitor cells","volume":"47","author":"Tozuka","year":"2005","journal-title":"Neuron"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB97|cit97","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.ntt.2008.01.004","article-title":"Effects of postnatal ethanol exposure at different developmental phases on neurotrophic factors and phosphorylated proteins on signal transductions in rat brain","volume":"30","author":"Tsuji","year":"2008","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB98|cit98","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/0028-3932(95)00096-8","article-title":"Spatial locations gone awry: object and spatial memory deficits in children with fetal alcohol syndrome","volume":"34","author":"Uecker","year":"1996","journal-title":"Neuropsychologia"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB99|cit99","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0741-8329(92)90057-H","article-title":"Prenatal ethanol effects: sex differences in offspring stress responsiveness","volume":"9","author":"Weinberg","year":"1992","journal-title":"Alcohol"},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB100|cit100","first-page":"515","article-title":"Prenatal ethanol exposure: pituitary-adrenal activity in pregnant dams and offspring","volume":"4","author":"Weinberg","year":"1982","journal-title":"Neurobehav. Toxicol. Teratol."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB101|cit101","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1111\/j.1365-2826.2008.01669.x","article-title":"Prenatal alcohol exposure: foetal programming, the hypothalamic-pituitary-adrenal axis and sex differences in outcome","volume":"20","author":"Weinberg","year":"2008","journal-title":"J. Neuroendocrinol."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB102|cit102","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1007\/s11064-007-9339-4","article-title":"Gender differences in the effects of prenatal stress on brain development and behaviour","volume":"32","author":"Weinstock","year":"2007","journal-title":"Neurochem. Res."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB103|cit103","first-page":"8","article-title":"Prenatal and early postnatal exposure to ethanol permanently alters the rat hippocampus","volume":"105","author":"West","year":"1984","journal-title":"Ciba Found. Symp."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB104|cit104","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1037\/0735-7044.104.1.116","article-title":"Behavioral and neuroanatomical effects of prenatal, postnatal, or combined exposure to ethanol in weanling rats","volume":"104","author":"Wigal","year":"1990","journal-title":"Behav. Neurosci."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB105|cit105","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.nbd.2004.08.006","article-title":"Apoptotic neurodegeneration induced by ethanol in neonatal mice is associated with profound learning\/memory deficits in juveniles followed by progressive functional recovery in adults","volume":"17","author":"Wozniak","year":"2004","journal-title":"Neurobiol. Dis."},{"key":"10.1111\/j.1460-9568.2011.07676.x-BIB106|cit106","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1006\/mcne.1998.0684","article-title":"Intraventricular administration of BDNF increases the number of newly generated neurons in the adult olfactory bulb","volume":"11","author":"Zigova","year":"1998","journal-title":"Mol. Cell. Neurosci."}],"container-title":["European Journal of Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1460-9568.2011.07676.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/j.1460-9568.2011.07676.x\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T10:22:05Z","timestamp":1741170125000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1460-9568.2011.07676.x"}},"subtitle":["Effects of physical exercise in a fetal alcohol syndrome model"],"short-title":[],"issued":{"date-parts":[[2011,5]]},"references-count":106,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2011,5]]}},"URL":"https:\/\/doi.org\/10.1111\/j.1460-9568.2011.07676.x","relation":{},"ISSN":["0953-816X"],"issn-type":[{"value":"0953-816X","type":"print"}],"subject":[],"published":{"date-parts":[[2011,5]]}}}