{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T00:11:57Z","timestamp":1790381517616,"version":"4.1.0"},"reference-count":42,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2006,3,30]],"date-time":"2006-03-30T00:00:00Z","timestamp":1143676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Anesthesia"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Background<\/jats:bold>\n                    :\u2002Video games have received widespread application in health care for distraction and behavior modification therapy. Studies on the effect of cognitive distraction during the preoperative period are lacking. We evaluated the efficacy of an interactive distraction, a hand\u2010held video game (VG) in reducing preoperative anxiety in children.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods<\/jats:bold>\n                    :\u2002In a randomized, prospective study of 112 children aged 4\u201312\u2003years undergoing outpatient surgery, anxiety was assessed after admission and again at mask induction of anesthesia, using the modified Yale Preoperative Anxiety Scale (mYPAS). Postoperative behavior changes were assessed with the Posthospital Behavior Questionnaire (PHBQ). Patients were randomly assigned to three groups: parent presence (PP), PP\u2003+\u2003a hand\u2010held VG, and PP\u2003+\u20030.5\u2003mg\u00b7kg\n                    <jats:sup>\u22121<\/jats:sup>\n                    oral midazolam (M) given &gt;20\u2003min prior to entering the operating room.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results<\/jats:bold>\n                    :\u2002There was a statistically significant increase in anxiety (\n                    <jats:italic>P<\/jats:italic>\n                    \u2003&lt;\u20030.01) in groups M and PP at induction of anesthesia compared with baseline, but not in VG group. VG patients demonstrated a decrease in anxiety from baseline (median change in mYPAS \u22123), the difference compared with PP (+11.8) was significant (\n                    <jats:italic>P<\/jats:italic>\n                    \u2003=\u20030.04). The change in anxiety in the M group (+7.3) was not statistically different from other groups. Sixty\u2010three percent of patients in VG group had no change or decrease in anxiety after treatment, compared with 26% in M group and 28% in PP group (\n                    <jats:italic>P<\/jats:italic>\n                    \u2003=\u20030.01). There was no difference in anxiety changes between female and male patients.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions<\/jats:bold>\n                    :\u2002A hand\u2010held VG can be offered to most children as a low cost, easy to implement, portable, and effective method to reduce anxiety in the preoperative area and during induction of anesthesia. Distraction in a pleasurable and familiar activity provides anxiety relief, probably through cognitive and motor absorption.\n                  <\/jats:p>","DOI":"10.1111\/j.1460-9592.2006.01914.x","type":"journal-article","created":{"date-parts":[[2006,3,30]],"date-time":"2006-03-30T03:56:03Z","timestamp":1143690963000},"page":"1019-1027","source":"Crossref","is-referenced-by-count":244,"title":["Distraction with a hand\u2010held video game reduces pediatric preoperative anxiety"],"prefix":"10.1111","volume":"16","author":[{"given":"ANURADHA","family":"PATEL","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"THOMAS","family":"SCHIEBLE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MELISSA","family":"DAVIDSON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MINH C. 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