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The ease with which propofol can be administered and titrated to clinical effect, in addition to its accepted safety profile, has made it the drug of choice for sedation in outpatient procedures, such as gastrointestinal endoscopy. While short\u2010term amnesia is a well\u2010known side\u2010effect of propofol, we present the first documented case of prolonged retrograde amnesia following propofol administration in a pediatric patient. 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