{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T03:21:17Z","timestamp":1778728877450,"version":"3.51.4"},"reference-count":21,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2011,4,4]],"date-time":"2011-04-04T00:00:00Z","timestamp":1301875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Anesthesia"],"published-print":{"date-parts":[[2011,8]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p><jats:bold>Background:\u2002<\/jats:bold> Many studies are reporting that the occurrence of hyperglycemia in the postoperative period is associated with increased morbidity and mortality rates in children after cardiac surgery for congenital heart disease. This study sought to determine blood glucose levels in standard pediatric cardiac anesthesiological management without insulin infusions.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> The study population consisted of 204 consecutive pediatric patients aged from 3\u2003days to 15.4\u2003years undergoing open cardiac surgery for congenital heart disease between June 2007 and January 2009. Glucose\u2010containing fluids were not administrated intraoperatively, and all patients received high dose of opioids (sufentanil 10\u2003mcg\u00b7kg<jats:sup>\u22121<\/jats:sup>) and steroids (30\u2003mg\u00b7kg<jats:sup>\u22121<\/jats:sup> methylprednisolone) iv. Glucose levels were measured before CPB, 10\u2003min after initiation of CPB, every hour on CPB, post\u2013CPB, and on arrival at intensive care unit (ICU).<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Intraoperatively, only one patient had a glucose level &lt;50\u2003mg\u00b7dl<jats:sup>\u22121<\/jats:sup> (=34.2\u2003mg\u00b7dl<jats:sup>\u22121<\/jats:sup>), 57\/204 patients (27.9%) had at least one intraoperative glucose &gt;180\u2003mg\u00b7dl<jats:sup>\u22121<\/jats:sup>, but only 12 patients (5.8%) had a glucose level &gt;180\u2003mg\u00b7dl<jats:sup>\u22121<\/jats:sup> at ICU arrival. Thirty\u2010day mortality was 1.5% (3\/204). Younger age, lower body weight, and lower CPB temperature were associated with hyperglycemia at ICU arrival, as were higher RACHS and Aristotle severity scores.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> A conventional (no insulin, no glucose) anesthetic management seems sufficient in the vast majority of patients (96.5%). Special attention should be paid to small neonates with complex congenital heart surgery, in whom insulin treatment may be contemplated.<\/jats:p>","DOI":"10.1111\/j.1460-9592.2011.03571.x","type":"journal-article","created":{"date-parts":[[2011,4,5]],"date-time":"2011-04-05T01:56:33Z","timestamp":1301968593000},"page":"872-879","source":"Crossref","is-referenced-by-count":10,"title":["Intraoperative glycemic control without insulin infusion during pediatric cardiac surgery for congenital heart disease"],"prefix":"10.1111","volume":"21","author":[{"given":"Thierry V.","family":"Scohy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanna D.","family":"Golab","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamud","family":"Egal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanna J.M.","family":"Takkenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ad J.J.C.","family":"Bogers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,4,4]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-1819"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.804286"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60044-1"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.PCC.0000227755.96700.98"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-0871"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0810625"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2009.08.008"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-0347"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.2009.03177.x"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.euje.2007.02.011"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-009-9512-4"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2004.03.027"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1067\/mtc.2002.119064"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.PCC.0000282164.16664.5D"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD005550.pub2"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2009.08.062"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/84.5.556"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199201023260101"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199005000-00007"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0952-8180(93)90101-J"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2005.05.107"}],"container-title":["Pediatric Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1460-9592.2011.03571.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1460-9592.2011.03571.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T03:25:57Z","timestamp":1698722757000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1460-9592.2011.03571.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4,4]]},"references-count":21,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2011,8]]}},"alternative-id":["10.1111\/j.1460-9592.2011.03571.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1460-9592.2011.03571.x","archive":["Portico"],"relation":{},"ISSN":["1155-5645","1460-9592"],"issn-type":[{"value":"1155-5645","type":"print"},{"value":"1460-9592","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,4,4]]}}}