{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T01:20:42Z","timestamp":1790817642763,"version":"4.1.0"},"reference-count":71,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2011,10,18]],"date-time":"2011-10-18T00:00:00Z","timestamp":1318896000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["enviromicro-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Environmental Microbiology"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Primary productivity in the ocean's oligotrophic regions is often limited by phosphorus (P) availability. In low phosphate environments, the prevalence of many genes involved in P acquisition is elevated, suggesting that the ability to effectively access diverse P sources is advantageous for organisms inhabiting these regions.\n                    <jats:italic>Prochlorococcus,<\/jats:italic>\n                    the numerically dominant primary producer in the oligotrophic ocean, encodes high\u2010affinity P transporters, P regulatory proteins and enzymes for organic phosphate utilization, but its ability to use reduced P compounds has not been previously demonstrated. Because\n                    <jats:italic>Prochlorococcus<\/jats:italic>\n                    strain MIT9301 encodes genes similar to\n                    <jats:italic>phnY<\/jats:italic>\n                    and\n                    <jats:italic>phnZ<\/jats:italic>\n                    , which constitute a novel marine bacterial 2\u2010aminoethylphosphonate (2\u2010AEPn) utilization pathway, it has been suggested that this organism might use 2\u2010AEPn as an alternative P source. We show here that although MIT9301 was unable to use 2\u2010AEPn as a sole P source under standard culture conditions, it was able to use phosphite. Phosphite utilization by MIT9301 appears to be mediated by an NAD\u2010dependent phosphite dehydrogenase encoded by\n                    <jats:italic>ptxD<\/jats:italic>\n                    . We show that phosphite utilization genes are present in diverse marine microbes and that their abundance is higher in low\u2010P waters. These results strongly suggest that phosphite represents a previously unrecognized component of the marine P cycle.\n                  <\/jats:p>","DOI":"10.1111\/j.1462-2920.2011.02612.x","type":"journal-article","created":{"date-parts":[[2011,10,18]],"date-time":"2011-10-18T00:49:19Z","timestamp":1318898959000},"page":"1363-1377","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":96,"title":["Phosphite utilization by the marine picocyanobacterium\n                    <i>Prochlorococcus<\/i>\n                    MIT9301"],"prefix":"10.1111","volume":"14","author":[{"given":"Asunci\u00f3n","family":"Mart\u00ednez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcia S.","family":"Osburne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian 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