{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T20:25:19Z","timestamp":1791491119946,"version":"4.3.4"},"reference-count":60,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,9,24]],"date-time":"2012-09-24T00:00:00Z","timestamp":1348444800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["enviromicro-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Environmental Microbiology"],"published-print":{"date-parts":[[2013,3]]},"abstract":"Summary<\/jats:title>\n \n Blue light is necessary for initiation of mushroom formation in\n \n S<\/jats:styled-content>\n chizophyllum commune\n <\/jats:italic>\n . The genome of this basidiomycete contains homologues of the blue light receptor genes\n \n wc\u20101<\/jats:italic>\n <\/jats:styled-content>\n and\n \n wc\u20102<\/jats:italic>\n <\/jats:styled-content>\n of\n \n N<\/jats:styled-content>\n eurospora crassa\n <\/jats:italic>\n . Here, it is shown that inactivation of either or both of these genes\n \n in\n S<\/jats:styled-content>\n .\u2009commune\n <\/jats:italic>\n results in a blind phenotype. Mushroom formation was abolished in dikaryons and they formed symmetrical instead of asymmetrical colonies. Development was restored in a temperature dependent way in a\n \n \u0394\n wc\u20102<\/jats:italic>\n \u0394\n wc\u20102<\/jats:italic>\n <\/jats:styled-content>\n strain by introducing a construct encompassing the\n \n wc\u20102<\/jats:italic>\n <\/jats:styled-content>\n gene under control of the promoter of the heat shock gene\n \n hsp3<\/jats:italic>\n <\/jats:styled-content>\n . A genome\u2010wide expression analysis showed that the transcription factor genes\n \n c2h2<\/jats:italic>\n <\/jats:styled-content>\n and\n \n hom1<\/jats:italic>\n <\/jats:styled-content>\n as well as many hydrophobin genes are downregulated in light\u2010grown colonies of the\n \n \u0394\n wc\u20102<\/jats:italic>\n \u0394\n wc\u20102<\/jats:italic>\n <\/jats:styled-content>\n mutant when compared with the wild\u2010type dikaryon. Inactivation of\n \n wc\u20101<\/jats:italic>\n <\/jats:styled-content>\n and\/or\n \n wc\u20102<\/jats:italic>\n <\/jats:styled-content>\n also resulted in sensitivity of the mycelium to intense light. Monokaryotic mutant strains only survived exposure to 6500\u2009lux of light by growing into the agar. Expression analysis indicates that the photosensitivity of the\n \n \u0394\n wc\u20101<\/jats:italic>\n <\/jats:styled-content>\n and\n \n \u0394\n wc\u20102<\/jats:italic>\n <\/jats:styled-content>\n strains is due to lower levels of photolyase and ferrochelatase.\n <\/jats:p>","DOI":"10.1111\/j.1462-2920.2012.02878.x","type":"journal-article","created":{"date-parts":[[2012,8,28]],"date-time":"2012-08-28T03:25:12Z","timestamp":1346124312000},"page":"943-955","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":83,"title":["The blue light receptor complex\n WC<\/scp>\n \u20101\/2 of\n \n S<\/scp>\n chizophyllum commune\n <\/i>\n is involved in mushroom formation and protection against phototoxicity"],"prefix":"10.1111","volume":"15","author":[{"given":"Robin A.","family":"Ohm","sequence":"first","affiliation":[{"name":"Department of Microbiology and Kluyver Centre for Genomics of Industrial Fermentations Utrecht University Padualaan 8 3584 CH Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Aerts","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Kluyver Centre for Genomics of Industrial Fermentations Utrecht University Padualaan 8 3584 CH Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han A. 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