{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T12:53:52Z","timestamp":1761742432341},"reference-count":5,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2004,8,27]],"date-time":"2004-08-27T00:00:00Z","timestamp":1093564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2004,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objective\u2002<\/jats:bold> Nicorandil is a vasodilator used to control angina. It has been associated with oral and anal ulceration that resolves upon withdrawal of the drug.<\/jats:p><jats:p><jats:bold>Patients and methods\u2002<\/jats:bold> We report a series of 13 patients with nonspecific anal ulceration all of whom were receiving nicorandil for control of symptoms of ischaemic heart disease.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> All the ulcers had similar clinical and histological appearances. All the ulcers healed on withdrawal of the drug.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Nicorandil\u2010associated anal ulceration shouldbe considered in the differential diagnoses of nonhealing anal ulcers.<\/jats:p>","DOI":"10.1111\/j.1463-1318.2004.00599.x","type":"journal-article","created":{"date-parts":[[2004,8,27]],"date-time":"2004-08-27T13:55:08Z","timestamp":1093614908000},"page":"330-331","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Nicorandil associated anal ulceration"],"prefix":"10.1111","volume":"6","author":[{"given":"A.","family":"Watson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Suttie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Fraser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"O'Kelly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Loudon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,8,27]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"132","article-title":"Major aphthous stomatitis induced by nicorandil","volume":"7","author":"Reichert S","year":"1997","journal-title":"Eur J Dermatol"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)61045-8"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/29.4.372"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)09710-6"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)11879-4"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1463-1318.2004.00599.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1463-1318.2004.00599.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T10:28:59Z","timestamp":1697452139000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1463-1318.2004.00599.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,8,27]]},"references-count":5,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2004,9]]}},"alternative-id":["10.1111\/j.1463-1318.2004.00599.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1463-1318.2004.00599.x","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,8,27]]},"assertion":[{"value":"2004-08-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}