{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T16:51:03Z","timestamp":1792342263158,"version":"4.4.0"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,11,2]],"date-time":"2005-11-02T00:00:00Z","timestamp":1130889600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Introduction\u2002<\/jats:bold> Diverticular disease is a common condition with high morbidity and mortality related to its complications. The aim of this study was to assess the predictive role of acute diverticulitis in the development of further complications from diverticular disease.<\/jats:p><jats:p><jats:bold>Patients and methods\u2002<\/jats:bold> Prospective assessment of all patients with complicated diverticular disease over a 1\u2010year period in a large teaching hospital was undertaken. All patients had documented evidence of their diagnosis by radiological, endoscopic or histopathological techniques when feasible.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Seventy\u2010seven patients with complicated diverticular disease were identified. There were 53 females and 24 males with a median age of 74\u2003years (range 30\u201397\u2003years). Complications included: acute diverticulitis (37), fistula (12), perforation (8), bleeding (7), abscess (7) and stricture (6). Only 8 had two or more previous documented episodes of diverticulitis. Twenty\u2010five underwent surgery, 3 died (peritonitis 2, abscess1) and 5 had a complication (anastomotic dehiscence 1, adhesive obstruction 1, incisional hernia 2 and pneumonia 1). Three (5%) of 37 patients with acute diverticulitis had two or more admissions but none underwent surgery or developed further complications. CT was performed during acute admission in 14\/37 patients with acute diverticulitis. The majority of patients with fistula (9\/12), perforation 7\/8, bleeding 6\/7 and abscess 5\/7 had no previous episode of diverticulitis while most patients with stricture (4\/6) had previous documented episodes.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> In our patient population acute diverticulitis is not a good predictor of the development of further complications from diverticular disease as only a minority of patients with perforation, fistula, abscess and bleeding had previous documented episodes of diverticulitis.<\/jats:p>","DOI":"10.1111\/j.1463-1318.2005.00865.x","type":"journal-article","created":{"date-parts":[[2005,11,2]],"date-time":"2005-11-02T11:45:19Z","timestamp":1130931919000},"page":"173-176","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Prospective study on the management of patients with complicated diverticular disease"],"prefix":"10.1111","volume":"8","author":[{"given":"T. A.","family":"Salem","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. G.","family":"Molloy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. J.","family":"O'Dwyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,11,2]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"117","article-title":"Long\u2010tem outcome of patients presenting with acute complications of diverticular disease","volume":"76","author":"Sarin S","year":"1994","journal-title":"Ann R Coll Surg Engl"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2004.03.001"},{"key":"e_1_2_5_4_2","first-page":"952","article-title":"Natural history of colonic diverticulosis","volume":"45","author":"Halphen M","year":"1995","journal-title":"Rev Pract"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004649901007"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02258291"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.4.5684.642"},{"key":"e_1_2_5_8_2","first-page":"85","article-title":"Treatment of perforated diverticular disease of the colon","volume":"12","author":"Hinchey EJ","year":"1978","journal-title":"Adv Surg"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004649900340"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199805213382107"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800810538"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198002073020605"},{"key":"e_1_2_5_13_2","first-page":"189","article-title":"Current management of diverticulitis","volume":"27","author":"Roberts PL","year":"1994","journal-title":"Adv Surg"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02049475"},{"key":"e_1_2_5_15_2","first-page":"156","article-title":"Acute left colonic diverticulitis in young patients","volume":"179","author":"Ambrosetti P","year":"1994","journal-title":"J Am Coll Surg"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1999.01501.x"},{"key":"e_1_2_5_17_2","first-page":"481","article-title":"The natural history of diverticular disease: is there a role for elective colectomy","volume":"47","author":"Somasekar K","year":"2002","journal-title":"J R Coll Surg Edinb"},{"key":"e_1_2_5_18_2","first-page":"445","article-title":"Is prophylactic resection valid as an indication for elective surgery in diverticular disease?","volume":"40","author":"Lorimer JW","year":"1997","journal-title":"Can J Surg"},{"key":"e_1_2_5_19_2","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/S0016-5085(76)80352-6","article-title":"Medical and Surgical therapy in diverticular disease A comparative study","volume":"71","author":"Larson DM","year":"1976","journal-title":"Gastroenterology"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-6336-4"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004230050257"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02237300"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1463-1318.2005.00865.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1463-1318.2005.00865.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T22:32:26Z","timestamp":1697409146000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1463-1318.2005.00865.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11,2]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,3]]}},"alternative-id":["10.1111\/j.1463-1318.2005.00865.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1463-1318.2005.00865.x","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,11,2]]},"assertion":[{"value":"2005-11-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}