{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T12:56:26Z","timestamp":1774270586651,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,6,30]],"date-time":"2007-06-30T00:00:00Z","timestamp":1183161600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objective\u2002<\/jats:bold> This study reports the results of injectable silicone PTQ<jats:sup>TM<\/jats:sup> implants for faecal incontinence due to internal anal sphincter (IAS) dysfunction.<\/jats:p><jats:p><jats:bold>Method\u2002<\/jats:bold> Twenty patients (12 women) with partial faecal incontinence aged from 55 to 65\u2003years were treated by a PTQ<jats:sup>TM<\/jats:sup> implant. All patients completed the Cleveland Clinic Continence and Quality of Life questionnaire. Endoluminal ultrasound and anorectal physiological testing were performed in each patient. All implants were inserted into the submucosal plane without ultrasound guidance.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Faecal continence was significantly improved up to 1\u2003year. The Wexner continence score fell from a median of 13.05 (range, 5\u201320) before treatment to 4.5 (range 2\u20137.7) at 1\u2003month after (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.005). This rose gradually to 6.2 (range, 0\u201316) at one year (<jats:italic>P<\/jats:italic>\u2003=\u20030.02) and 9.4 (range, 1\u201320) at 2\u2003years (<jats:italic>P<\/jats:italic>\u2003=\u20030.127). There were no differences in resting or squeeze pressure before and at 3\u2003months after treatment (<jats:italic>P<\/jats:italic>\u2003=\u20030.86 and <jats:italic>P<\/jats:italic>\u2003=\u20030.93). Fourteen (70%) patients experienced pruritus ani during the first few weeks after the procedure and one developed infection at the implant site.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Silicone implantation is minimally invasive and technically simple. It is effective over 1\u2003year in the treatment of faecal incontinence due to IAS dysfunction.<\/jats:p>","DOI":"10.1111\/j.1463-1318.2007.01276.x","type":"journal-article","created":{"date-parts":[[2007,6,30]],"date-time":"2007-06-30T13:24:49Z","timestamp":1183209889000},"page":"89-94","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Evaluation of the use of PTQ<sup>TM<\/sup><i>implants<\/i> for the treatment of incontinent patients due to internal anal sphincter dysfunction"],"prefix":"10.1111","volume":"10","author":[{"given":"F.","family":"De La Portilla","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Le\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Rada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Cisneros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. 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