{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T16:00:11Z","timestamp":1794412811888,"version":"4.9.1"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,1,10]],"date-time":"2012-01-10T00:00:00Z","timestamp":1326153600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim\u2002<\/jats:bold> Doppler\u2010guided transanal haemorrhoid dearterialization (THD) and stapler haemorrhoidopexy (SH) have been demonstrated to be less painful than the Milligan\u2013Morgan procedure. The aim of this study was to compare the effectiveness of THD <jats:italic>vs<\/jats:italic> SH in the treatment of third\u2010degree haemorrhoids in an equivalent trial.<\/jats:p><jats:p><jats:bold>Method\u2002<\/jats:bold> One hundred and sixty\u2010nine patients with third\u2010degree haemorrhoids were randomized online to receive THD (<jats:italic>n<\/jats:italic>\u2003=\u200385) or SH (<jats:italic>n<\/jats:italic>\u2003=\u200384) in 10 Colorectal Units in which the staff were well trained in both techniques. The mean follow\u2010up period was 17\u2003(range 15\u201320) months.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Early minor postoperative complications occurred in 30.6% of patients in the THD group and in 32.1% of patients in the SH group. Milder spontaneous pain and pain on defecation were reported in the THD group in the first postoperative week, but this was not statistically significant. Late complications were significantly higher (<jats:italic>P<\/jats:italic>\u2003=\u20030.028) in the SH group. Residual haemorrhoids persisted in 12 patients in the THD group and in six patients in the SH group (<jats:italic>P<\/jats:italic>\u2003=\u20030.14). Six patients in the SH group and 10 in the THD group underwent further treatment of haemorrhoids (<jats:italic>P<\/jats:italic>\u2003=\u20030.34). No differences were found in postoperative incontinence. The obstructed defecation score (ODS) was significantly higher in the SH group (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.02). Improvement in quality of life was similar in both groups. Postoperative in\u2010hospital stay was 1.14\u2003days in the THD group and 1.31\u2003days in the SH group (<jats:italic>P<\/jats:italic>\u2003=\u20030.03).<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Both THD and SH techniques are effective for the treatment of third\u2010degree haemorrhoids in the medium term. THD has a better cost\u2010effective ratio and lower (not significant) pain compared with SH. Postoperative pain and recurrence did not differ significantly between the two groups.<\/jats:p>","DOI":"10.1111\/j.1463-1318.2011.02628.x","type":"journal-article","created":{"date-parts":[[2011,3,29]],"date-time":"2011-03-29T15:00:11Z","timestamp":1301410811000},"page":"205-211","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":85,"title":["Prospective randomized multicentre study comparing stapler haemorrhoidopexy with Doppler\u2010guided transanal haemorrhoid dearterialization for third\u2010degree haemorrhoids"],"prefix":"10.1111","volume":"14","author":[{"given":"A.","family":"Infantino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. F.","family":"Altomare","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Bottini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Bonanno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Mancini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the THD group of the SICCR (Italian Society of Colorectal Surgery) (T. Yalti, P. Giamundo, J. Hoch, A. El Gaddal and C. 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Proceeding of the 6th world Congress of Endoscopic Surgery \u2013 Rome Monduzzi Editore Bologna1998 777\u201384."},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anchir.2004.05.008"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0399-8320(05)80798-5"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02632-5"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02208-X"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.137.12.1395"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-008-0391-0"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-006-0277-y"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-0921-4"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.03.008"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181af50f4"},{"key":"e_1_2_7_14_2","first-page":"93","volume-title":"Surgery of the Anus, Rectum and Colon","author":"Goligher JC","year":"1980"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02050307"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2007.01262.x"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2009.01915.x"},{"key":"e_1_2_7_18_2","first-page":"509","article-title":"PATE 2000 Sorrento: a modern, effective instrument for defining haemorrhoids. A multicentre observational study conducted in 930 symptomatic patients","volume":"56","author":"Gaj F","year":"2004","journal-title":"Chir Ital"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.3310\/hta12080"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2008.01638.x"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6078"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-008-0611-0"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-007-0376-4"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181cdafa7"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-744"},{"key":"e_1_2_7_26_2","first-page":"947","article-title":"Doppler\u2010guided ligation of the hemorrhoidal arteries. 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