{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T10:05:39Z","timestamp":1771063539833,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2012,6,8]],"date-time":"2012-06-08T00:00:00Z","timestamp":1339113600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim\u2002<\/jats:bold> In patients with familial adenomatous polyposis (FAP), removal of the colonic mucosa is essential to reduce the lifetime risk of developing cancer). For this purpose, ileo\u2010pouch anal anastomosis (IPAA) has been the gold standard, but morbidity related to the dissection of the pelvis remains substantial. In an attempt to reduce the procedure\u2010related complications of pelvic dissection, ileoneo\u2010rectal anastomosis (INRA) has been developed. In this case series of FAP patients, the long\u2010term functional results, morbidity and quality of life (QoL) of the INRA procedure were evaluated and compared with its early outcome.<\/jats:p><jats:p><jats:bold>Method\u2002<\/jats:bold> Long\u2010term follow up of a consecutive group of eight FAP patients with an INRA procedure (between 1998 and 2005) was undertaken. Data on functional results, complications, manometry and endoscopy were recorded prospectively.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Eight patients with FAP underwent the INRA procedure. The median number of defaecations over 24\u2003h was five. No pelvic sepsis or bladder dysfunction occurred. One patient, in whom concomitant Crohn\u2019s disease was diagnosed in retrospect, was converted to IPAA. In the INRA patients, no sexual dysfunction occurred. Endoscopic examination showed normal mucosa without any evidence of polyp formation.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Restorative surgery by means of the INRA procedure yields good functional results in FAP patients, without any pelvic dissection\u2010related morbidity or regrowth of polyps in the neo\u2010rectum.<\/jats:p>","DOI":"10.1111\/j.1463-1318.2011.02806.x","type":"journal-article","created":{"date-parts":[[2011,9,4]],"date-time":"2011-09-04T02:24:38Z","timestamp":1315103078000},"page":"861-865","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The ileo neo\u2010rectal anastomosis in patients with familial adenomatous polyposis: a prospective case series with long\u2010term follow up"],"prefix":"10.1111","volume":"14","author":[{"given":"S.","family":"de Zeeuw","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. T.","family":"Heikens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. G.","family":"Gooszen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. J. H. 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