{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T04:55:25Z","timestamp":1764996925920},"reference-count":23,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2012,8,22]],"date-time":"2012-08-22T00:00:00Z","timestamp":1345593600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim\u2002<\/jats:bold> Colonoscopy provides imperfect protection against colorectal cancer (CRC).<\/jats:p><jats:p>In an attempt to improve cancer detection we evaluated the clinical features of invasive CRC detected within 5\u2003years of a negative colonoscopy.<\/jats:p><jats:p><jats:bold>Method\u2002<\/jats:bold> The details of colonoscopies performed in a rural hospital in Japan were prospectively recorded at the time of the examination. The patients were followed over 5\u2003years for the subsequent occurrence of cancer.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> In a 5\u2010year period, 10\u2003148 patients underwent colonoscopy and 202 without previous colonoscopy were diagnosed with invasive CRC. Of 3212 patients with a colonoscopy negative for cancer, nine developed invasive cancer within 5\u2003years. The ratios for invasive CRC detected without\/with previous colonoscopy were 60:1 in the rectum, 54:1 in the sigmoid colon, 15:1 in the descending colon, 28:0 in the transverse colon, 31:5 in the ascending colon and 14:1 in the caecum (<jats:italic>P<\/jats:italic>\u2003=\u20030.041). The ratio between left\u2010 and right\u2010sided colonic cancer was also significantly different (129:3 and 45:6, <jats:italic>P<\/jats:italic>\u2003=\u20030.0078). Six (67%) of the invasive CRCs were in the ascending colon or caecum. Five of six patients with invasive CRC in the ascending colon and caecum had right\u2010sided small adenomas at prior colonoscopy.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> The majority of early\/missed CRCs were right\u2010sided and associated with prior right\u2010sided colonic adenomas. Repeated colonoscopy of patients with right\u2010sided adenomas at a shorter surveillance interval deserves consideration.<\/jats:p>","DOI":"10.1111\/j.1463-1318.2011.02892.x","type":"journal-article","created":{"date-parts":[[2011,11,22]],"date-time":"2011-11-22T13:14:09Z","timestamp":1321967649000},"page":"1090-1094","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Invasive colorectal cancer within 5\u2003years of negative colonoscopy in a Japanese population"],"prefix":"10.1111","volume":"14","author":[{"given":"A.","family":"Horiuchi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Nakayama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Kajiyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Kamijima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,8,22]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199312303292701"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1997.v112.agast970594"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(97)70214-2"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2006.00905.x"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-39665"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.05.032"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.05.012"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2006.10.027"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.650"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2010.390"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1255868"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-150-1-200901060-00306"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djp436"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19980101)82:1<60::AID-CNCR7>3.0.CO;2-O"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2006.07.012"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2006.10.022"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2003.07453.x"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1542-3565(04)00664-0"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2010.429"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0907667"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2006.00606.x"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01555.x"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2009.08.018"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1463-1318.2011.02892.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1463-1318.2011.02892.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T05:21:35Z","timestamp":1698729695000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1463-1318.2011.02892.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8,22]]},"references-count":23,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["10.1111\/j.1463-1318.2011.02892.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1463-1318.2011.02892.x","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,8,22]]},"assertion":[{"value":"2012-08-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}