{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:17:38Z","timestamp":1758475058043},"reference-count":18,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2012,10,9]],"date-time":"2012-10-09T00:00:00Z","timestamp":1349740800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim\u2002<\/jats:bold> Treatment of giant condyloma acuminatum, is controversial, especially in human immunodeficiency virus (HIV)\u2010positive patients, owing to concern over wound healing, complications, risk of progression to carcinoma and a high recurrence rate. The aim of this study was to evaluate the outcome after extensive local excision with V\u2013Y anoplasty.<\/jats:p><jats:p><jats:bold>Method\u2002<\/jats:bold> Nine patients were identified from a prospective database, six of whom were HIV positive. All patients had a giant perianal condyloma acuminatum extending into the anal canal and perianal region, which required wide excision with V\u2013Y reconstruction. Postoperative complications, recurrence and continence were all determined.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Nine patients were included (eight men, median age 40\u2003years), six seropositive for HIV infection. A bilateral V\u2013Y anoplasty was performed in six patients, and unilateral in two. There were no postoperative infections, graft failures or flap necrosis. The mean follow\u2010up was 92 (2\u2013137) months. One patient developed local recurrence treated with excision under local anaesthesia.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> Extensive local surgery of giant perianal condyloma with anoplastic reconstruction gives good results even in HIV\u2010positive patients.<\/jats:p>","DOI":"10.1111\/j.1463-1318.2012.03006.x","type":"journal-article","created":{"date-parts":[[2012,2,22]],"date-time":"2012-02-22T19:21:00Z","timestamp":1329938460000},"page":"1394-1397","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Management of giant anal condyloma by wide local excision and anoplasty"],"prefix":"10.1111","volume":"14","author":[{"given":"N.","family":"Uribe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Rueda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z.","family":"Balciscueta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. 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