{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T06:03:28Z","timestamp":1783663408684,"version":"3.55.0"},"reference-count":26,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2012,10,9]],"date-time":"2012-10-09T00:00:00Z","timestamp":1349740800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Complete mesocolic excision (CME) with central vessel ligation (CVL) as performed in Erlangen offers the best long\u2010term outcome for colon cancer. The aim of this study was to assess specimens after laparoscopic <jats:italic>vs<\/jats:italic> open CME\u2010CVL macroscopically and morphometrically in patients with left and right colon cancers.<\/jats:p><jats:p><jats:bold>Method\u2002<\/jats:bold> All specimens were freshly photographed. Precise tumour morphometry and grading of the surgical plane were performed as described by pathologists in Leeds, UK.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Thirty\u2010four specimens from right\u2010sided cancers were divided into 18 transverse colon cancers (nine laparoscopic <jats:italic>vs<\/jats:italic> nine open) and 16 caecum\u2013ascending colon cancers (seven laparoscopic <jats:italic>vs<\/jats:italic> nine open) and 56 specimens from left\u2010sided cancers (33 laparoscopic <jats:italic>vs<\/jats:italic> 23 open). There was no difference between laparoscopically and open acquired left\u2010 and right\u2010sided specimens. Specimens of transverse colon displayed differences in length of central ligation to tumour (open 11.67\u2003cm <jats:italic>vs<\/jats:italic> laparoscopic 8.72\u2003cm, <jats:italic>P<\/jats:italic>\u2003=\u20030.049), length of central ligation to bowel wall (open 9.11\u2003cm <jats:italic>vs<\/jats:italic> laparoscopic 6.5\u2003cm, <jats:italic>P<\/jats:italic>\u2003=\u20030.015) and lymph node clearance (open 46.33 <jats:italic>vs<\/jats:italic> laparoscopic 39.33, <jats:italic>P<\/jats:italic>\u2003=\u20030.033).<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Laparoscopy seems to offer specimens of similar quality after CME\u2010CVL surgery for colon cancer to the open approach. Issues of completeness of excision from laparoscopy are raised for tumours located in the transverse colon.<\/jats:p>","DOI":"10.1111\/j.1463-1318.2012.03019.x","type":"journal-article","created":{"date-parts":[[2012,3,6]],"date-time":"2012-03-06T03:27:08Z","timestamp":1331004428000},"page":"1357-1364","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":87,"title":["Complete mesocolic excision in colon cancer surgery: a comparison between open and laparoscopic approach"],"prefix":"10.1111","volume":"14","author":[{"given":"N.","family":"Gouvas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Pechlivanides","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Zervakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Kafousi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Xynos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,10,9]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)91510-2"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60485-2"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-6317-7"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2008.01735.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(08)70181-5"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.24.1448"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2007.11.015"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2008.03.011"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12032-010-9514-3"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2008.10.020"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-006-9243-1"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-007-0378-8"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02048026"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032651"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.142.3.298"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)66545-2"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-009-0348-z"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-009-0551-x"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djk092"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.05.062"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2009.10.003"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-007-9368-x"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.06.8866"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2007.08.030"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-008-0540-y"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-6673-3"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1463-1318.2012.03019.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1463-1318.2012.03019.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T06:09:53Z","timestamp":1698732593000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1463-1318.2012.03019.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,9]]},"references-count":26,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["10.1111\/j.1463-1318.2012.03019.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1463-1318.2012.03019.x","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,9]]},"assertion":[{"value":"2012-10-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}