{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T12:18:38Z","timestamp":1768738718111,"version":"3.49.0"},"reference-count":35,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2012,9,11]],"date-time":"2012-09-11T00:00:00Z","timestamp":1347321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim\u2002<\/jats:bold> Sacral nerve stimulation (SNS) reduces symptoms in up to 80% of patients with faecal incontinence (FI). Its effects are not limited to the distal colon and the pelvic floor. Accordingly, spinal or supraspinal neuromodulation have been suggested as part of the mode of action. The effect of SNS on gastric and small\u2010intestinal motility was studied.<\/jats:p><jats:p><jats:bold>Method\u2002<\/jats:bold> Using the magnet tracking system, MTS\u20101, a small magnetic pill was tracked twice through the upper gastrointestinal tract of eight patients with FI successfully treated with SNS. Following a randomized double\u2010blind crossover design, the stimulator was either left active or was turned off for 1\u2003week before investigations with MTS\u20101.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> The median (range) frequency of gastric con\u2010tractions was 3.05 (2.83\u20133.40) per min during SNS and 3.04 (2.79?\u20133.76) per min without (<jats:italic>P<\/jats:italic>\u2003=\u2003NS). The median (range) frequency of contractions in the small intestine during the first 2\u2003h after pyloric passage was 10.005 (9.68\u201310.70) per min during SNS and 10.09 (9.79\u201310.29) per min without SNS (<jats:italic>P<\/jats:italic>\u2003=\u2003NS). The median (range) velocity of the magnetic pill during the first 2\u2003h in the small intestine was 1.6 (1.2\u20132.8) cm\/min during SNS and 1.7 (0.8\u20133.7) cm\/min without SNS (<jats:italic>P<\/jats:italic>\u2003=\u2003NS). Small\u2010intestinal propagation mainly occurred during very fast movements (&gt;\u200315\u2003cm\/min), accounting for 51% (42\u201360%) of the distance 3% (2\u20134%) of the time during SNS and for 53% (18\u201373%) of the distance 3% (1\u20138%) of the time without SNS (<jats:italic>P\u2003<\/jats:italic>=\u2003NS).<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Turning off SNS for 1\u2003week did not affect gastric or small\u2010intestinal motility patterns.<\/jats:p>","DOI":"10.1111\/j.1463-1318.2012.03148.x","type":"journal-article","created":{"date-parts":[[2012,6,27]],"date-time":"2012-06-27T19:27:50Z","timestamp":1340825270000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Turning off sacral nerve stimulation does not affect gastric and small intestinal motility in patients treated for faecal incontinence"],"prefix":"10.1111","volume":"14","author":[{"given":"J.","family":"Wors\u00f8e","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Fassov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Schlageter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. 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