{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T16:10:48Z","timestamp":1781194248615,"version":"3.54.1"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,2,27]],"date-time":"2013-02-27T00:00:00Z","timestamp":1361923200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim\u2002<\/jats:bold> Colorectal polyps with a focus of malignancy, identified postpolypectomy, pose a management challenge of whether endoscopic treatment is adequate or whether further surgical resection is required. This study assessed 12\u2010 and 20\u2010MHz colonoscopic ultrasound to evaluate the presence of residual disease and local lymph nodes.<\/jats:p><jats:p><jats:bold>Method\u2002<\/jats:bold> Consecutive cases of all colorectal polyps with a focus of malignancy were included. Colonoscopic high\u2010frequency ultrasound was performed (20\u2010MHz mini\u2010probes for residual polyps and 12\u2010MHz ultrasound for local lymph nodes) in the region of previous polypectomy. Biopsies were taken of the polypectomy site if any abnormalities were seen.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Twenty\u2010one malignant polyps (sigmoid, <jats:italic>n<\/jats:italic>\u2003=\u200310; rectum, <jats:italic>n<\/jats:italic>\u2003=\u20038; transverse colon, <jats:italic>n<\/jats:italic>\u2003=\u20031; ascending colon, <jats:italic>n<\/jats:italic>\u2003=\u20031; and caecum, <jats:italic>n<\/jats:italic>\u2003=\u20031) were identified. All were invasive adenocarcinomas; 12 were intramucosal and nine were submucosal (seven sm1 lesions in the upper third of the submucosa; and two sm2 lesions in the middle third of the submucosa). Excision was histologically complete in 12 patients, four had involved margins and histology was uncertain in five owing to diathermy artefacts. Further colonoscopy revealed a residual abnormality in eight patients. The 12\u2010 and 20\u2010MHz ultrasound imaging revealed mucosal irregularity with normal bowel\u2010wall layers and no lymph\u2010node involvement, with normal histology. High\u2010frequency ultrasound was normal in the remaining 13 patients. At the time of writing, 15 (72%) of the 21 patients were disease free without further surgery. Six of the 21 patients underwent surgery, despite normal high\u2010frequency ultrasound findings, because of submucosal invasion (sm1 or sm2) and uncertain completeness of resection. The specimens were free of cancer in all six patients.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> High\u2010frequency ultrasound is feasible for the assessment of colorectal malignant polyps.<\/jats:p>","DOI":"10.1111\/j.1463-1318.2012.03180.x","type":"journal-article","created":{"date-parts":[[2012,7,10]],"date-time":"2012-07-10T05:29:16Z","timestamp":1341898156000},"page":"304-308","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["High\u2010frequency mini\u2010probe ultrasound as a useful adjunct in the management of patients with malignant colorectal polyps"],"prefix":"10.1111","volume":"15","author":[{"given":"A.","family":"Haji","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Ryan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Bjarnason","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Papagrigoriadis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,2,27]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0016-5085(73)80091-5","article-title":"Distribution of human colonic lymphatics in normal, hyperplastic, and adenomatous tissue. Its relationship to metastasis from small carcinomas in pedunculated adenomas, with two case reports","volume":"64","author":"Fenoglio CM","year":"1973","journal-title":"Gastroenterology"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02049154"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-005-0063-3"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-004-0903-6"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(94)70262-4"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200102000-00001"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800790206"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800791032"},{"key":"e_1_2_8_10_2","first-page":"495","article-title":"Male and female sexual and urinary function after total mesorectal excision with autonomic nerve preservation for carcinoma of the rectum","volume":"182","author":"Havenga K","year":"1996","journal-title":"J Am Coll Surg"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198112000-00008"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(85)90333-6"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.25.5.437"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.211.1.r99ap1231"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1463-1318.2012.03180.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1463-1318.2012.03180.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T20:40:53Z","timestamp":1697661653000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1463-1318.2012.03180.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,27]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["10.1111\/j.1463-1318.2012.03180.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1463-1318.2012.03180.x","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,27]]},"assertion":[{"value":"2013-02-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}