{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T18:50:03Z","timestamp":1775155803468,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"s1","license":[{"start":{"date-parts":[[2011,9,16]],"date-time":"2011-09-16T00:00:00Z","timestamp":1316131200000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>An 11\u2010year\u2010old, neutered male domestic short\u2010hair cat was presented with buphthalmos of the right eye and diagnosed with advanced glaucoma. Sonographic examination revealed an iridial thickening. Neoplasia was suspected and an enucleation was performed. Histopathology of the enucleated eye revealed abundant amyloid deposition predominantly in the anterior uveal tract accompanied by few to moderate numbers of well\u2010differentiated plasma cells. The amyloid deposits were identified by staining with Congo red and showing green birefringence under polarized light. Immunohistochemically, amyloid and plasma cells stained intensely only with anti\u2010AL\u03bb antibody, supporting the amyloid tumor being an immunoglobulin\u2010\u03bb\u2010light chain origin. Additional abnormalities included narrowing of the filtration angle and collapse of the ciliary cleft, and trabecular meshwork. One year post\u2010enucleation, the cat was still healthy without signs of systemic amyloidosis or apparent metastatic disease. This is the first report of a cat with noncutaneous extramedullary plasmacytoma originating in the anterior uveal tract with resulting local amyloid.<\/jats:p>","DOI":"10.1111\/j.1463-5224.2011.00900.x","type":"journal-article","created":{"date-parts":[[2011,9,16]],"date-time":"2011-09-16T19:32:17Z","timestamp":1316201537000},"page":"88-92","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Intraocular AL\u03bb amyloidoma with plasma cell neoplasia in a cat"],"prefix":"10.1111","volume":"14","author":[{"given":"Olivia","family":"Kershaw","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Linek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reinhold P.","family":"Linke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Achim D.","family":"Gruber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,9,16]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/030098589002700514"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9975(08)80246-0"},{"issue":"11","key":"e_1_2_4_4_2","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.2460\/javma.1989.195.11.1593","article-title":"Extramedullary plasmacytoma and immunoglobulin\u2010associated amyloidosis in a cat","volume":"195","author":"Carothers MA","year":"1989","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1987.tb05970.x"},{"issue":"6","key":"e_1_2_4_6_2","first-page":"603","article-title":"A retroperitoneal extramedullary plasmacytoma in a cat with a monoclonal gammopathy","volume":"30","author":"Mandel NS","year":"1994","journal-title":"Journal of the American Animal Hospital Association"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9975(97)80042-4"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/030098589403100317"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.4065\/81.5.693"},{"key":"e_1_2_4_10_2","volume-title":"Histological Classification of Hematopoietic Tumors of Domestic Animals","author":"Valli V","year":"2002"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2006.tb00754.x"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.1354\/vp.40-3-249"},{"key":"e_1_2_4_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00176888"},{"key":"e_1_2_4_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1463-5224.2003.00277.x"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/NEN.0b013e31819a87f9"},{"key":"e_1_2_4_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.acthis.2006.03.010"},{"key":"e_1_2_4_17_2","doi-asserted-by":"publisher","DOI":"10.1354\/vp.45-2-159"},{"key":"e_1_2_4_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0442.1996.tb00489.x"},{"key":"e_1_2_4_19_2","first-page":"355","volume-title":"Veterinary Ophthalmology","author":"Grahn BH","year":"2007"},{"key":"e_1_2_4_20_2","doi-asserted-by":"publisher","DOI":"10.1354\/vp.40-4-355"}],"container-title":["Veterinary Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1463-5224.2011.00900.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1463-5224.2011.00900.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T14:18:54Z","timestamp":1741702734000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1463-5224.2011.00900.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":19,"journal-issue":{"issue":"s1","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["10.1111\/j.1463-5224.2011.00900.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1463-5224.2011.00900.x","archive":["Portico"],"relation":{},"ISSN":["1463-5216","1463-5224"],"issn-type":[{"value":"1463-5216","type":"print"},{"value":"1463-5224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9]]},"assertion":[{"value":"2011-09-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}