{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:29:54Z","timestamp":1790789394890,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,2,28]],"date-time":"2012-02-28T00:00:00Z","timestamp":1330387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Objective\u2002<\/jats:bold>\n                    To describe the incidence, clinical progress, visual outcome, and laboratory findings of equine keratomycosis in Japan.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Procedure\u2002<\/jats:bold>\n                    Retrospective study of the medical records of horses clinically and mycologically diagnosed with keratomycosis at the Equine Hospitals of the Japan Racing Association from 2005 to 2011.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results\u2002<\/jats:bold>\n                    The diagnosis of keratomycosis was confirmed in eight horses (40.0% of the 20 horses with infectious keratitis from which fungi and\/or bacteria were isolated). Fungi recovered from corneal swabs were identified as\n                    <jats:italic>Aspergillus flavus<\/jats:italic>\n                    (4),\n                    <jats:italic>Aspergillus niger<\/jats:italic>\n                    (1),\n                    <jats:italic>Fusarium solani<\/jats:italic>\n                    (1), and\n                    <jats:italic>Mortierella wolfii<\/jats:italic>\n                    (2). All horses were treated medically with topical antifungals, and one horse was also treated surgically. The median of treatment period was 40\u2003days. Two horses were rendered blind in the affected eye and the others retained vision.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions\u2002<\/jats:bold>\n                    Equine keratomycosis comprises a considerable portion of infectious keratitis in Japan, and the causative fungi that we isolated had been isolated previously from horses with keratomycosis in other regions with the exception of\n                    <jats:italic>M.\u00a0wolfii<\/jats:italic>\n                    . Culture and cytological examination of corneal lesions should be immediately performed on eyes with signs of keratitis, particularly on those not improving with antibacterial medication, as early initiation of aggressive antifungal treatment tended to result in better outcome and shorter treatment period.\n                  <\/jats:p>","DOI":"10.1111\/j.1463-5224.2012.01004.x","type":"journal-article","created":{"date-parts":[[2012,2,28]],"date-time":"2012-02-28T09:07:18Z","timestamp":1330420038000},"page":"1-9","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Equine keratomycosis in Japan"],"prefix":"10.1111","volume":"16","author":[{"given":"Shinya","family":"Wada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seiji","family":"Hobo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotaka","family":"Ode","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidekazu","family":"Niwa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidekazu","family":"Moriyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,2,28]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"crossref","first-page":"105","DOI":"10.2460\/javma.1998.213.01.105","article-title":"Clinical appearances, healing patterns, risk factors, and outcomes of horse with fungal keratitis: 53 cases (1978\u20101996)","volume":"213","author":"Gaader JE","year":"1998","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/09286580601001347"},{"key":"e_1_2_6_4_2","doi-asserted-by":"crossref","first-page":"468","DOI":"10.26719\/2011.17.6.468","article-title":"Climate change and predicted trend of fungal keratitis in Egypt","volume":"17","author":"Saad\u2010Hussein A","year":"2011","journal-title":"Eastern Mediterranean Health Journal"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/B0-72-160522-2\/50007-8"},{"key":"e_1_2_6_6_2","first-page":"85","volume-title":"Ophthalmology for the Equine Practitioner","author":"Brooks DE","year":"2008"},{"key":"e_1_2_6_7_2","first-page":"1165","volume-title":"Veterinary Ophthalmology","author":"Brooks DE","year":"2007"},{"key":"e_1_2_6_8_2","first-page":"676","article-title":"Antifungal sensitivity testing for equine keratomycosis","volume":"46","author":"Coad CT","year":"1985","journal-title":"American Journal of Veterinary Research"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1998.tb04469.x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"crossref","first-page":"138","DOI":"10.2460\/ajvr.1998.59.02.138","article-title":"Antimicrobial susceptibility patterns from horses with ulcerative keratomycosis","volume":"59","author":"Brooks DE","year":"1998","journal-title":"American Journal of Veterinary Research"},{"key":"e_1_2_6_11_2","first-page":"600","article-title":"Bacterial and fungal isolate from Equidae with ulcerative keratitis","volume":"183","author":"Moore CP","year":"1983","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_6_12_2","doi-asserted-by":"crossref","first-page":"928","DOI":"10.2460\/javma.1995.207.07.0928","article-title":"Antibacterial susceptibility patterns for microbial isolates associated with infectious keratitis in horses: 63 cases (1986\u20101994)","volume":"207","author":"Moore CP","year":"1995","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.156.1.13"},{"key":"e_1_2_6_14_2","first-page":"489","article-title":"Aspergillus oryzae as a cause of keratomycosis in the horse","volume":"12","author":"Marolt J","year":"1984","journal-title":"Tierrztliche Praxis"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1080\/02681219780000871"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1463-5224.2003.00286.x"},{"key":"e_1_2_6_17_2","first-page":"64","article-title":"Clinical aspects of mycotic keratitis in the horse","volume":"69","author":"Bistner SI","year":"1979","journal-title":"Cornell Veterinarian"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-9846(17)30003-4"},{"key":"e_1_2_6_19_2","first-page":"1240","article-title":"Conjunctival fungal flora in horses, cattle, dogs, and cats","volume":"184","author":"Samuelson DA","year":"1984","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1463-5224.2003.00267.x"},{"key":"e_1_2_6_21_2","first-page":"107","volume-title":"Equine Ophthalmology. 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