{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T16:12:11Z","timestamp":1779034331801,"version":"3.51.4"},"reference-count":41,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,6,8]],"date-time":"2006-06-08T00:00:00Z","timestamp":1149724800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2006,7]]},"abstract":"<jats:sec>\n                    <jats:label\/>\n                    <jats:p>In this section, many different issues are written about by authors from the UK, France, the Netherlands, the USA and Denmark, respectively. Topics covered are botulinum toxin in drug\u2010resistant neurogenic detrusor overactivity in spinal cord injury, dutasteride and BPH, the effect of childbirth on bothersome LUTS, female urethral strictures, and a new bulking agent in treating female stress urinary incontinence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVES<\/jats:title>\n                    <jats:p>To assess, in a prospective study, whether botulinum toxin\u2010type A (BTX\u2010A) injected into the detrusor muscle, can be used as a day\u2010case treatment for drug\u2010resistant neurogenic detrusor overactivity (NDO) in patients with spinal cord injury (SCI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PATIENTS AND METHODS<\/jats:title>\n                    <jats:p>BTX\u2010A (Dysport, Ipsen, Luxembourg; 1000\u2003units) was injected cystoscopically into the detrusor muscle of 37 patients with drug\u2010resistant NDO and SCI, as a day\u2010case procedure. The maximum cystometric capacity (MCC), maximum detrusor pressure (MDP), NDO, continence, and anticholinergic requirement were used as outcome variables. The International Consultation on Incontinence questionnaire (ICIQ) was used to assess the patient\u2019s quality of life before and after the BTX\u2010A injection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      The mean follow\u2010up was 7\u2003months. The MCC increased from a mean of 259\u2003to 522\u2003mL, and the MDP decreased from a mean of 54 to 24\u2003cmH\n                      <jats:sub>2<\/jats:sub>\n                      O. Incontinence and NDO were abolished in 82% and 76% patients, respectively. In all, 86% of the patients were able to stop or reduce anticholinergics, with a similar proportion of patients scoring favourably on the ICIQ. The mean duration of improvement was 9\u2003months.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Injection with BTX\u2010A is an effective day\u2010case treatment that bridges the gap between oral and invasive surgical treatment of drug\u2010resistant NDO in patients with SCI.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/j.1464-410x.2006.06192.x","type":"journal-article","created":{"date-parts":[[2006,6,8]],"date-time":"2006-06-08T13:33:44Z","timestamp":1149773624000},"page":"77-82","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["Botulinum toxin\u2010type A in the treatment of drug\u2010resistant neurogenic detrusor overactivity secondary to traumatic spinal cord injury"],"prefix":"10.1111","volume":"98","author":[{"given":"PRASAD S.","family":"PATKI","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RIZWAN","family":"HAMID","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KIRUPAKAR","family":"ARUMUGAM","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. 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