{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T16:34:42Z","timestamp":1761755682159,"version":"build-2065373602"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,8,2]],"date-time":"2006-08-02T00:00:00Z","timestamp":1154476800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2006,9]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To investigate whether the gonadotrophin\u2010releasing hormone (GnRH) test is an adequate diagnostic tool to identify testicular dysfunction in men with strictly unilateral varicocele and defined testicular volume; and to identify any peripheral venous variable which would predict the result of the GnRH test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PATIENTS AND METHODS<\/jats:title>\n                    <jats:p>In all, 102 GnRH tests were done in men with a left\u2010sided varicocele. Follicle\u2010stimulating hormone (FSH) and luteinizing hormone (LH) levels were determined. After intravenous administration of 100\u2003\u00b5g GnRH, stimulated LH and FSH levels were measured. FSH levels of &gt;8.2\u2003U\/L and LH levels of &gt;51.7\u2003U\/L were considered exaggerated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      In all, 50 men had an exaggerated GnRH test result; all had an exaggerated FSH response and six also had an elevated LH response. The baseline FSH levels were higher (\n                      <jats:italic>P<\/jats:italic>\n                      \u2003&lt;\u20030.001) and the testicular volume was smaller (\n                      <jats:italic>P<\/jats:italic>\n                      \u2003&lt;\u20030.01) in men with an exaggerated GnRH test response. All men with a baseline FSH level of &gt;5.6\u2003U\/L had an exaggerated GnRH test response.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>A baseline FSH level of &gt;5.6\u2003U\/L is a good predictor of the GnRH test outcome. Leydig cell function seems mainly undisturbed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/j.1464-410x.2006.06367.x","type":"journal-article","created":{"date-parts":[[2006,8,2]],"date-time":"2006-08-02T16:19:08Z","timestamp":1154535548000},"page":"619-622","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Baseline follicle\u2010stimulating hormone is a strong predictor for the outcome of the gonadotrophin\u2010releasing hormone test in young men with unilateral medium\u2010 or high\u2010grade 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