{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T04:53:17Z","timestamp":1764996797155,"version":"build-2065373602"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,11,7]],"date-time":"2006-11-07T00:00:00Z","timestamp":1162857600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2007,1]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To morphometrically compare local atherosclerotic changes in cancerous prostate with those in noncancerous prostate specimens, as epidemiological studies report a positive association between the prevalence of general atherosclerosis and prostate cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>MATERIALS AND METHODS<\/jats:title>\n                    <jats:p>The intima\u2010to\u2010media\u2010ratio (IMR) of 538 prostate capsular tissue arteries was measured in 50 prostate cancer\u2010positive and 29 prostate cancer\u2010negative specimens (including 26 with benign prostatic hyperplasia and three with normal prostatic tissue).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>An IMR of &gt;1 was significantly associated with prostate cancer and a greater risk of prostate cancer (odds ratio 2.28). The IMR was &gt;1 in cancer\u2010positive specimens about twice as often as in cancer\u2010negative tissue.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>Local atherosclerosis (measured by the IMR) was more pronounced in prostate cancer\u2010positive than in prostate cancer\u2010negative specimens. 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