{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:03:16Z","timestamp":1791327796764,"version":"4.3.1"},"reference-count":20,"publisher":"Wiley","issue":"4b","license":[{"start":{"date-parts":[[2012,9,3]],"date-time":"2012-09-03T00:00:00Z","timestamp":1346630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2013,4]]},"abstract":"\n \n Study Type \u2013 Therapy (case series)<\/jats:p>\n Level of Evidence\u20034<\/jats:p>\n \n What's known on the subject? and What does the study add?<\/jats:bold>\n <\/jats:p>\n Artifical Urinary Sphincter (AUS) is the treatment of choice for moderate to severe post\u2010radical prostatectomy incontinence with good long\u2010term outcomes despite risk of complications.<\/jats:p>\n We report preliminary results of a new preconnected AUS (ZSI 375). Main change with the device currently available is the replacement of the abdominal reservoir by a pressure\u2010regulated spring in the intrascrotal pump avoiding abdominal approach.<\/jats:p>\n <\/jats:sec>\n \n OBJECTIVE<\/jats:title>\n \n \n \n To assess retrospectively the safety and efficacy of an artificial urinary sphincter, the ZSI 375 device (Zephyr Surgical Implants, Geneva, Switzerland), in male patients with moderate\u2010to\u2010severe stress urinary incontinence after a prostate or bladder intervention.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n PATIENTS AND METHODS<\/jats:title>\n \n \n \n The ZSI 375 device is a one\u2010piece device consisting of an adjustable cuff, moulded to fit around the urethra, which is connected by a tube to a pump and a pressure\u2010regulating tank. It has no abdominal reservoir.<\/jats:p>\n <\/jats:list-item>\n \n Patients underwent a perineal incision for cuff placement and an inguinal incision for pump and tank scrotal placement.<\/jats:p>\n <\/jats:list-item>\n \n Complications and pads used to manage incontinence were recorded.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n RESULTS<\/jats:title>\n \n \n \n Between May 2009 and April 2011, 36 patients underwent ZSI 375 device placement. The median (range) follow\u2010up was 15.4 (6\u201328) months.<\/jats:p>\n <\/jats:list-item>\n \n No patient experienced bladder overactivity, chronic urinary retention, or any other adverse effect after device activation. Complications leading to device removal arose in four patients (one case of erosion, three cases of infection).<\/jats:p>\n <\/jats:list-item>\n \n Social continence (0 or 1 pad\/day) was achieved in 28\/36 patients (78%) at 3 months and 26\/36 patients (73%) at 6 months after device activation.<\/jats:p>\n <\/jats:list-item>\n \n \n In 12\/14 patients for a sphincter closure pressure range of 60\u201370\u2003cm H\n 2<\/jats:sub>\n O, in 3\/3 patients for a range of 70\u201380\u2003cm H\n 2<\/jats:sub>\n O and in 2\/11 for a range of 90\u2013100\u2003cm, H\n 2<\/jats:sub>\n O social continence was achieved only after increasing the pressure of the cuff by trans\u2010scrotal injection of saline.\n <\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS<\/jats:title>\n \n \n \n The ZSI 375 device is safe and effective but our follow\u2010up may not have been long enough to identify all potential complications.<\/jats:p>\n <\/jats:list-item>\n \n Further research is needed to confirm these results and extend our investigation, for instance, to the peno\u2010scrotal approach.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/j.1464-410x.2012.11468.x","type":"journal-article","created":{"date-parts":[[2012,9,3]],"date-time":"2012-09-03T05:16:40Z","timestamp":1346649400000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["ZSI 375 artificial urinary sphincter for male urinary incontinence: a preliminary study"],"prefix":"10.1111","volume":"111","author":[{"given":"Frederic","family":"Staerman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"G\u2010Llorens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priscilla","family":"Leon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Leclerc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,9,3]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(73)90749-8"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20844"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)36057-3"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)65088-4"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)64082-7"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000152315.91444.d0"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)63557-2"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.10.062"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1743-6109.2010.01933.x"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2011.05.048"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2011.03.020"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1159\/000019817"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)67285-0"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)65668-6"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.01.048"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2004.09.042"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.10.062"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.11.058"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.07.068"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.10.157"}],"container-title":["BJU 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