{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:15:17Z","timestamp":1761128117186},"reference-count":15,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2004,7,29]],"date-time":"2004-07-29T00:00:00Z","timestamp":1091059200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetic Medicine"],"published-print":{"date-parts":[[2004,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim\u2003<\/jats:bold> The aim of the study was to establish whether diurnal blood glucose profiles differed in women with gestational diabetes (GDM) with different forms of hypertensive complications.<\/jats:p><jats:p><jats:bold>Methods\u2003<\/jats:bold> The subjects were patients diagnosed at 26\u201332 gestational weeks as having GDM (<jats:italic>n<\/jats:italic>\u00a0=\u00a0178). They were classified as being normotensive, having chronic hypertension (with or without superimposed pre\u2010eclampsia on chronic hypertension) or pregnancy\u2010induced hypertension (with or without proteinuria). We compared diurnal blood glucose profiles (blood glucose taken every 4\u00a0h over 24\u00a0h) in these three groups.<\/jats:p><jats:p><jats:bold>Results\u2003<\/jats:bold> Hypertension complicated 43% of the women with GDM. The glucose profiles were similar between the three groups, except that in early morning hours (from 04:00 to 08:00\u00a0h) blood glucose concentrations increased in mothers with chronic hypertension, whereas they decreased in the normotensive women. In univariate regression analysis, both obesity (BMI\u00a0\u2265\u00a028\u00a0kg\/m<jats:sup>2<\/jats:sup>) and chronic hypertension showed significant association with blood glucose rise from 04:00 to 08:00\u00a0h, but in a multiple regression model neither showed significant independent effect.<\/jats:p><jats:p><jats:bold>Conclusions\u2003<\/jats:bold> The rise in blood glucose levels during the early morning hours in women with GDM and chronic hypertension could reflect greater insulin resistance and sympathetic overactivity.<\/jats:p>","DOI":"10.1111\/j.1464-5491.2004.01314.x","type":"journal-article","created":{"date-parts":[[2004,10,20]],"date-time":"2004-10-20T08:53:22Z","timestamp":1098262402000},"page":"1181-1184","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Diurnal blood glucose profiles in women with gestational diabetes with or without hypertension"],"prefix":"10.1111","volume":"21","author":[{"given":"A.","family":"Leinonen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Hiilesmaa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Andersen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Teramo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Kaaja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,20]]},"reference":[{"key":"e_1_2_7_2_2","first-page":"S77","article-title":"Gestational Diabetes Mellitus","volume":"23","author":"American Diabetes Association.","year":"2000","journal-title":"Diabetes Care"},{"key":"e_1_2_7_3_2","unstructured":"Hyv\u00f6nenK.Gestaatiodiabeteksen esiintyvyys ja seulonta. [The incidence and screening of gestational diabetes mellitus in Finland (in Finnish with English summary).]Publications of the University of Kuopio Finland 1991."},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(90)90652-N"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016349309068036"},{"key":"e_1_2_7_6_2","first-page":"B27","article-title":"Hypertension in women with gestational diabetes","volume":"21","author":"Roberts R","year":"1998","journal-title":"Diabetes Care"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(90)91306-W"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(99)00341-5"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0026-0495(99)90225-1"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(98)70210-8"},{"key":"e_1_2_7_11_2","first-page":"29","article-title":"Random capillary blood glucose and conventional selection criteria for glucose tolerance testing during pregnancy","volume":"2","author":"Stangenberg M","year":"1985","journal-title":"Diabetes Res"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.36.4.538"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.3109\/10641959909023077"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199611143352002"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1998.tb10179.x"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-7061(00)00225-9"}],"container-title":["Diabetic Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1464-5491.2004.01314.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1464-5491.2004.01314.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T21:00:09Z","timestamp":1697230809000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1464-5491.2004.01314.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,10,20]]},"references-count":15,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2004,11]]}},"alternative-id":["10.1111\/j.1464-5491.2004.01314.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1464-5491.2004.01314.x","archive":["Portico"],"relation":{},"ISSN":["0742-3071","1464-5491"],"issn-type":[{"value":"0742-3071","type":"print"},{"value":"1464-5491","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,10,20]]},"assertion":[{"value":"2004-10-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}