{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T05:48:41Z","timestamp":1793944121418,"version":"4.8.0"},"reference-count":143,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,3,21]],"date-time":"2005-03-21T00:00:00Z","timestamp":1111363200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetic Medicine"],"published-print":{"date-parts":[[2005,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Animal models have been used extensively in diabetes research. Early studies used pancreatectomised dogs to confirm the central role of the pancreas in glucose homeostasis, culminating in the discovery and purification of insulin. Today, animal experimentation is contentious and subject to legal and ethical restrictions that vary throughout the world. Most experiments are carried out on rodents, although some studies are still performed on larger animals. Several toxins, including streptozotocin and alloxan, induce hyperglycaemia in rats and mice. Selective inbreeding has produced several strains of animal that are considered reasonable models of Type\u00a01 diabetes, Type\u00a02 diabetes and related phenotypes such as obesity and insulin resistance. Apart from their use in studying the pathogenesis of the disease and its complications, all new treatments for diabetes, including islet cell transplantation and preventative strategies, are initially investigated in animals. In recent years, molecular biological techniques have produced a large number of new animal models for the study of diabetes, including knock\u2010in, generalized knock\u2010out and tissue\u2010specific knockout mice.<\/jats:p>","DOI":"10.1111\/j.1464-5491.2005.01499.x","type":"journal-article","created":{"date-parts":[[2005,3,21]],"date-time":"2005-03-21T09:38:41Z","timestamp":1111397921000},"page":"359-370","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":489,"title":["Animal models of diabetes mellitus"],"prefix":"10.1111","volume":"22","author":[{"given":"D. A.","family":"Rees","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. C.","family":"Alcolado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,3,21]]},"reference":[{"key":"e_1_2_15_2_2","volume-title":"Animal Models of Diabetes: A Primer.","author":"Sima AAF","year":"2000"},{"key":"e_1_2_15_3_2","unstructured":"British Union for the Abolition of Vivisection.Home page. Available from:http:\/\/www.buav.org."},{"key":"e_1_2_15_4_2","volume-title":"Eternal Treblinka. Our Treatment of Animals and the Holocaust","author":"Patterson C.","year":"2002"},{"key":"e_1_2_15_5_2","volume-title":"Defending Animal Rights.","author":"Regan T.","year":"2001"},{"key":"e_1_2_15_6_2","first-page":"78","article-title":"Science and society. Different bioethical approaches towards animal experimentation","volume":"19","author":"Brom FW.","year":"2002","journal-title":"ALTEX"},{"key":"e_1_2_15_7_2","volume-title":"Animal (Scientific Procedures) Act 1986.","year":"1986"},{"key":"e_1_2_15_8_2","volume-title":"Guidance on the Operation of the Animals (Scientific Procedures) Act 1986.","year":"2000"},{"key":"e_1_2_15_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/374670a0"},{"key":"e_1_2_15_10_2","unstructured":"Diabetes UK.Animal Research. Position Statement from Diabetes UK.2002. Available from:http:\/\/www.Diabetes.org.uk\/infocentre\/state\/animals.html."},{"key":"e_1_2_15_11_2","doi-asserted-by":"crossref","DOI":"10.3138\/9781442621480","volume-title":"The Discovery of Insulin","author":"Bliss M.","year":"2000"},{"key":"e_1_2_15_12_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI106180"},{"key":"e_1_2_15_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02341500"},{"key":"e_1_2_15_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2001.tb03663.x"},{"key":"e_1_2_15_15_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1442-9071.2001.00409.x"},{"key":"e_1_2_15_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1999.tb07822.x"},{"key":"e_1_2_15_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0026-0495(95)90223-6"},{"key":"e_1_2_15_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840080224"},{"key":"e_1_2_15_19_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118387"},{"key":"e_1_2_15_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(88)90633-9"},{"key":"e_1_2_15_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1071-5576(03)00044-3"},{"key":"e_1_2_15_22_2","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1016\/S0022-2275(20)31606-0","article-title":"Age\u2010related changes in cholesterol metabolism in macrosomic offspring of rats with streptozotocin\u2010induced diabetes","volume":"42","author":"Merzouk H","year":"2001","journal-title":"J Lipid Res"},{"key":"e_1_2_15_23_2","doi-asserted-by":"publisher","DOI":"10.1159\/000017367"},{"key":"e_1_2_15_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0950-3552(05)80108-7"},{"key":"e_1_2_15_25_2","doi-asserted-by":"publisher","DOI":"10.2337\/diab.34.2.S42"},{"key":"e_1_2_15_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2003.08.066"},{"key":"e_1_2_15_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001090050337"},{"key":"e_1_2_15_28_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000073613.25658.4D"},{"key":"e_1_2_15_29_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200003150-00015"},{"key":"e_1_2_15_30_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.29.5.341"},{"key":"e_1_2_15_31_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000061770.39569.7F"},{"key":"e_1_2_15_32_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200104270-00002"},{"key":"e_1_2_15_33_2","doi-asserted-by":"crossref","first-page":"513","DOI":"10.3727\/000000002783985576","article-title":"Successful single donor islet allotransplantation in the streptozotocin diabetes rat model","volume":"11","author":"Jahr H","year":"2002","journal-title":"Cell Transplantation"},{"key":"e_1_2_15_34_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.50.5.1021"},{"key":"e_1_2_15_35_2","doi-asserted-by":"publisher","DOI":"10.1042\/bj3150271"},{"key":"e_1_2_15_36_2","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1152\/ajplegacy.1958.195.2.331","article-title":"Some quantitative studies on Phlorizin inhibition of glucose transport in the kidney","volume":"195","author":"Lotspeich WD","year":"1958","journal-title":"Am J Physiol"},{"key":"e_1_2_15_37_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03345212"},{"key":"e_1_2_15_38_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-004-1350-6"},{"key":"e_1_2_15_39_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111751200"},{"key":"e_1_2_15_40_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.50.2007.S108"},{"key":"e_1_2_15_41_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.46.6.947"},{"key":"e_1_2_15_42_2","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1681\/ASN.V351078","article-title":"Effects of hyperglycaemia on glucose transporters of the muscle: use of the renal glucose reabsorption inhibitor Phlorizin to control glycemia","volume":"3","author":"Dimitrakoudis D","year":"1992","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_15_43_2","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/j.1651-2227.1998.tb01244.x","article-title":"diabetes: an epidemiological perspective","volume":"425","author":"Dahlquist G.","year":"1998","journal-title":"Acta Paetriatr Suppl"},{"key":"e_1_2_15_44_2","first-page":"699","article-title":"Review of mechanism of action studies of the nitrosureas","volume":"60","author":"Bono VH.","year":"1976","journal-title":"Cancer Treat Rep"},{"key":"e_1_2_15_45_2","doi-asserted-by":"crossref","first-page":"50","DOI":"10.2337\/diab.47.1.50","article-title":"GLUT2 in pancreatic islets: crucial target molecule in diabetes induced with multiple low\u2010doses of streptozotocin in mice","volume":"47","author":"Wang Z","year":"1998","journal-title":"Diabetes"},{"key":"e_1_2_15_46_2","first-page":"101","article-title":"Kinetic behaviour of liver glucokinase in diabetes. I. Alteration in streptozotocin\u2010diabetic rats","volume":"14","author":"Zahner D","year":"1990","journal-title":"Diabetes Res"},{"key":"e_1_2_15_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1383-5742(02)00044-3"},{"key":"e_1_2_15_48_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006676-200305000-00021"},{"key":"e_1_2_15_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-5890(02)00021-4"},{"key":"e_1_2_15_50_2","doi-asserted-by":"publisher","DOI":"10.1078\/0171-2985-00109"},{"key":"e_1_2_15_51_2","doi-asserted-by":"publisher","DOI":"10.1006\/jaut.2001.0506"},{"key":"e_1_2_15_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0162-3109(99)00149-6"},{"key":"e_1_2_15_53_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02786324"},{"key":"e_1_2_15_54_2","doi-asserted-by":"publisher","DOI":"10.3109\/08916939509001931"},{"key":"e_1_2_15_55_2","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-206-43725"},{"key":"e_1_2_15_56_2","doi-asserted-by":"publisher","DOI":"10.1538\/expanim1978.29.1_1"},{"key":"e_1_2_15_57_2","doi-asserted-by":"publisher","DOI":"10.1038\/9442"},{"key":"e_1_2_15_58_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.19.8560"},{"key":"e_1_2_15_59_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4615-0171-8_9"},{"key":"e_1_2_15_60_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.50.11.2451"},{"key":"e_1_2_15_61_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1043-2760(99)00210-6"},{"key":"e_1_2_15_62_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2001.tb05650.x"},{"key":"e_1_2_15_63_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001250100021"},{"key":"e_1_2_15_64_2","doi-asserted-by":"crossref","first-page":"100","DOI":"10.2337\/diab.26.2.100","article-title":"The spontaneously diabetic wistar rat. Metabolic and morphological studies","volume":"26","author":"Nakhooda AF","year":"1977","journal-title":"Diabetes"},{"key":"e_1_2_15_65_2","first-page":"1","volume-title":"Animal Models of Diabetes: a Primer.","author":"Mordes JP","year":"2001"},{"key":"e_1_2_15_66_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001090050301"},{"key":"e_1_2_15_67_2","doi-asserted-by":"publisher","DOI":"10.3109\/08916939809008041"},{"key":"e_1_2_15_68_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.45.6.749"},{"key":"e_1_2_15_69_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006676-198902000-00015"},{"key":"e_1_2_15_70_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001250051621"},{"key":"e_1_2_15_71_2","doi-asserted-by":"publisher","DOI":"10.1006\/jaut.1996.0092"},{"key":"e_1_2_15_72_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.284.5417.1183"},{"key":"e_1_2_15_73_2","doi-asserted-by":"publisher","DOI":"10.3109\/08916930109008047"},{"key":"e_1_2_15_74_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-065x.2001.1840115.x"},{"key":"e_1_2_15_75_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.48.1.50"},{"key":"e_1_2_15_76_2","doi-asserted-by":"publisher","DOI":"10.1038\/371161a0"},{"key":"e_1_2_15_77_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(00)00467-7"},{"key":"e_1_2_15_78_2","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.2337\/diab.46.11.1711","article-title":"Cow's milk\u2010free diet does not prevent diabetes in NOD mice","volume":"46","author":"Paxson JA","year":"1997","journal-title":"Diabetes"},{"key":"e_1_2_15_79_2","doi-asserted-by":"crossref","first-page":"133","DOI":"10.2337\/diab.46.7.1133","article-title":"Dietary cow's milk protein does not alter the frequency of diabetes in the BB rat","volume":"46","author":"Malkani S","year":"1997","journal-title":"Diabetes"},{"key":"e_1_2_15_80_2","doi-asserted-by":"publisher","DOI":"10.1053\/meta.2002.31979"},{"key":"e_1_2_15_81_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI17005"},{"key":"e_1_2_15_82_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0042-6822(03)00462-8"},{"key":"e_1_2_15_83_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.23.12097-12111.2002"},{"key":"e_1_2_15_84_2","doi-asserted-by":"publisher","DOI":"10.1080\/ann.34.3.138.147"},{"key":"e_1_2_15_85_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001250051614"},{"key":"e_1_2_15_86_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.165.5.2866"},{"key":"e_1_2_15_87_2","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1210\/endo.139.1.5641","article-title":"diabetes in nonobese diabetic mice by late intervention with nonhypercalcemic analogues of 1,25 dihydroxyvitamin D3 in combination with a short induction course of cyclosporin A","volume":"139","author":"Casteels KM","year":"1998","journal-title":"Endocrinology"},{"key":"e_1_2_15_88_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.39.4.508"},{"key":"e_1_2_15_89_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.40.6.715"},{"key":"e_1_2_15_90_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-8411(05)80034-4"},{"key":"e_1_2_15_91_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI119654"},{"key":"e_1_2_15_92_2","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1490223"},{"key":"e_1_2_15_93_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1993.tb17169.x"},{"key":"e_1_2_15_94_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.26.12.3326"},{"key":"e_1_2_15_95_2","doi-asserted-by":"publisher","DOI":"10.1080\/ann.34.3.207.217"},{"key":"e_1_2_15_96_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0950-351X(96)80330-2"},{"key":"e_1_2_15_97_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.53.2007.S103"},{"key":"e_1_2_15_98_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.51.31937"},{"key":"e_1_2_15_99_2","doi-asserted-by":"publisher","DOI":"10.1016\/0168-9525(96)30103-0"},{"key":"e_1_2_15_100_2","doi-asserted-by":"publisher","DOI":"10.1038\/372425a0"},{"key":"e_1_2_15_101_2","doi-asserted-by":"publisher","DOI":"10.1038\/379632a0"},{"key":"e_1_2_15_102_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng0596-18"},{"key":"e_1_2_15_103_2","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.119.85"},{"key":"e_1_2_15_104_2","first-page":"S84","article-title":"diabetes","volume":"50","author":"Mrialles F","year":"2001","journal-title":"Diabetes"},{"key":"e_1_2_15_105_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng0196-31"},{"key":"e_1_2_15_106_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng0196-38"},{"key":"e_1_2_15_107_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.48.12.2463"},{"key":"e_1_2_15_108_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2004.01225.x"},{"key":"e_1_2_15_109_2","first-page":"159","article-title":"Rodent models of nephropathy associated with type II diabetes","volume":"12","author":"Janssen U","year":"1999","journal-title":"J Nephrol"},{"key":"e_1_2_15_110_2","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.326"},{"key":"e_1_2_15_111_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001250050740"},{"key":"e_1_2_15_112_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01222198"},{"key":"e_1_2_15_113_2","doi-asserted-by":"publisher","DOI":"10.1016\/0168-8227(94)90268-2"},{"key":"e_1_2_15_114_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.52.8.2175"},{"key":"e_1_2_15_115_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.50.8.1943"},{"key":"e_1_2_15_116_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00400717"},{"key":"e_1_2_15_117_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.48.5.1168"},{"key":"e_1_2_15_118_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0026-0495(99)90244-5"},{"key":"e_1_2_15_119_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(91)90419-X"},{"key":"e_1_2_15_120_2","first-page":"47","article-title":"From sand rats to diabetic patients: is non\u2010insulin dependent diabetes mellitus a disease of the \u03b2 cell?","volume":"23","author":"Cerasi E","year":"1997","journal-title":"Diabetes Metabol"},{"key":"e_1_2_15_121_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00296.2001"},{"key":"e_1_2_15_122_2","doi-asserted-by":"publisher","DOI":"10.2337\/diab.41.11.1422"},{"key":"e_1_2_15_123_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00335-002-2199-y"},{"key":"e_1_2_15_124_2","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.60.373"},{"key":"e_1_2_15_125_2","doi-asserted-by":"publisher","DOI":"10.1007\/s003359900869"},{"key":"e_1_2_15_126_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1996.tb00498.x"},{"key":"e_1_2_15_127_2","doi-asserted-by":"crossref","first-page":"16034","DOI":"10.1016\/S0021-9258(17)33969-8","article-title":"Expression of a dominant\u2010negative mutant human insulin receptor in the muscle of transgenic mice","volume":"269","author":"Chang PY","year":"1994","journal-title":"J Biol Chem"},{"key":"e_1_2_15_128_2","doi-asserted-by":"publisher","DOI":"10.1038\/372182a0"},{"key":"e_1_2_15_129_2","doi-asserted-by":"publisher","DOI":"10.1038\/36116"},{"key":"e_1_2_15_130_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.49.11.1880"},{"key":"e_1_2_15_131_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(95)90235-X"},{"key":"e_1_2_15_132_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.23.11346"},{"key":"e_1_2_15_133_2","doi-asserted-by":"publisher","DOI":"10.1038\/81649"},{"key":"e_1_2_15_134_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80546-2"},{"key":"e_1_2_15_135_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R300009200"},{"key":"e_1_2_15_136_2","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.23.20.7222-7229.2003"},{"key":"e_1_2_15_137_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R300019200"},{"key":"e_1_2_15_138_2","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1210\/endo.142.5.8148","article-title":"Minireview: tissue\u2010specific versus generalized gene targeting of the IGF1 and IGR1R genes and their roles in insulin\u2010like growth factor physiology","volume":"145","author":"Butler AA","year":"2001","journal-title":"Endocrinology"},{"key":"e_1_2_15_139_2","doi-asserted-by":"publisher","DOI":"10.2337\/diab.40.2.S106"},{"key":"e_1_2_15_140_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-004-1464-x"},{"key":"e_1_2_15_141_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.51.5.1499"},{"key":"e_1_2_15_142_2","doi-asserted-by":"publisher","DOI":"10.1155\/EDR.2001.139"},{"key":"e_1_2_15_143_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.2003.00011.x"},{"key":"e_1_2_15_144_2","doi-asserted-by":"publisher","DOI":"10.1375\/1369052012597"}],"container-title":["Diabetic Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1464-5491.2005.01499.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1464-5491.2005.01499.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T10:57:49Z","timestamp":1696935469000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1464-5491.2005.01499.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,3,21]]},"references-count":143,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,4]]}},"alternative-id":["10.1111\/j.1464-5491.2005.01499.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1464-5491.2005.01499.x","archive":["Portico"],"relation":{},"ISSN":["0742-3071","1464-5491"],"issn-type":[{"value":"0742-3071","type":"print"},{"value":"1464-5491","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,3,21]]},"assertion":[{"value":"2005-03-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}