{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T19:54:34Z","timestamp":1762113274187},"reference-count":29,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2011,8,15]],"date-time":"2011-08-15T00:00:00Z","timestamp":1313366400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetic Medicine"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:sec><jats:label \/><jats:p>Diabet. Med. 28, 1045\u20131052 (2011)<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aims\u2002<\/jats:bold> In a cohort of men and women with Type\u20031 diabetes, prospectively followed for &gt;\u200320\u2003years, vibrotactile sense in fingers was investigated and related to neurophysiological tests, glycaemic level and clinical score.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Out of 58 patients, diagnosed at the age of 15\u201325\u2003years and recruited 1984\u20131985, 32 patients (13 women, median age 52\u2003years, range 44\u201375\u2003years; 19 men, median age 52\u2003years, range 39\u201369\u2003years; median duration 33.5\u2003years, range 21\u201352\u2003years) accepted follow\u2010up in 2006. Vibration thresholds were measured in finger pulps of index and little fingers bilaterally at seven frequencies and related to results of touch (monofilaments), tactile discrimination (two\u2010point discrimination test), electrophysiology (median nerve function), glycaemic level (HbA<jats:sub>1c<\/jats:sub> levels since 1984\u20131985) and a clinical score.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Vibrotactile sense was reduced in finger pulps, mainly in men, compared with an age\u2010 and gender\u2010matched healthy control group with normal HbA<jats:sub>1c<\/jats:sub>. Vibration thresholds were increased, particularly at 250 and 500\u2003Hz, in both index and little finger pulps. Touch and tactile discrimination correlated with vibration thresholds, but not with each other or with electrophysiology. HbA<jats:sub>1c<\/jats:sub> levels (at follow\u2010up or mean values from five follow\u2010ups since recruitment) did not correlate with any nerve function variables. Clinical scores correlated with vibrotactile sense, particularly at higher frequencies (&gt;\u2003125\u2003Hz), but not with total Z\u2010scores of electrophysiology. Duration of disease did not correlate with any variables.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> Examination of vibration thresholds in index and little finger pulps may be valuable to detect neuropathy, where thresholds correlate with symptoms and tests.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1464-5491.2011.03328.x","type":"journal-article","created":{"date-parts":[[2011,8,15]],"date-time":"2011-08-15T12:49:36Z","timestamp":1313412576000},"page":"1045-1052","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Disturbed vibrotactile sense in finger pulps in patients with Type\u20031 diabetes\u2014correlations with glycaemic level, clinical examination and electrophysiology"],"prefix":"10.1111","volume":"28","author":[{"given":"L. 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