{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T19:08:38Z","timestamp":1774379318246,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,12,7]],"date-time":"2011-12-07T00:00:00Z","timestamp":1323216000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetic Medicine"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:sec><jats:label\/><jats:p>Diabet. Med. 29, 70\u201373 (2012)<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aims\u2003<\/jats:bold> Exercise may be useful to detect patients with diabetes prone to develop persistent microalbuminuria. We studied the relationship between exercise intensity, measured as maximal oxygen consumption (VO<jats:sub>2<\/jats:sub>\u2003max), and microalbuminuria in patients with Type\u20031 diabetes mellitus patients.<\/jats:p><jats:p><jats:bold>Methods\u2003<\/jats:bold> We studied 10 patients, age range 10\u201318\u2003years, with Type\u20031 diabetes who were normotensive and normoalbuminuric, with less than 10\u2003years since diagnosis. Patients had normal renal function, without infections or clinical evidence of complications. Metabolic control was intensively adjusted in all patients. They underwent three consecutive physical exercise tests, reaching 100, 80 and 60% of the maximal cardiac frequency response.<\/jats:p><jats:p><jats:bold>Results\u2003<\/jats:bold> Eight patients had adequate to regular metabolic control. All patients had lower than predicted VO<jats:sub>2<\/jats:sub>\u2003max values. At 60%, only three patients showed microalbuminuria in excess of 20\u2003\u03bcg\/min, two of them had inadequate metabolic control. Post\u2010exercise microalbuminuria exceeded normal values in nine, seven and three patients when submitted to 100, 80 and 60% of exercise intensity, respectively.<\/jats:p><jats:p><jats:bold>Conclusions\u2003<\/jats:bold> Microalbuminuria increased with exercise intensity. Sex, body composition and VO<jats:sub>2<\/jats:sub>\u2003max were the main factors associated with microalbuminuria. The prognostic significance of albuminuria induced by intense exercise in these subjects with Type\u20031 diabetes is not yet known.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1464-5491.2011.03380.x","type":"journal-article","created":{"date-parts":[[2011,7,4]],"date-time":"2011-07-04T17:40:44Z","timestamp":1309801244000},"page":"70-73","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Effect of exercise intensity on albuminuria in adolescents with Type\u20031 diabetes mellitus"],"prefix":"10.1111","volume":"29","author":[{"given":"C.","family":"Kornhauser","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.\u2010M.","family":"Malacara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.\u2010H.","family":"Mac\u00edas\u2010Cervantes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.\u2010E.","family":"Rivera\u2010Cisneros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,12,7]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00640673"},{"key":"e_1_2_8_3_2","doi-asserted-by":"crossref","first-page":"E261","DOI":"10.25011\/cim.v32i4.6616","article-title":"Prevalence and duration of exercise\u2010induced albuminuria in healthy people","volume":"32","author":"Heathcote KL","year":"2009","journal-title":"Clin Invest Med"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-972876"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.2165\/00007256-199418060-00006"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365519009091561"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00257792"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00280880"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004670050168"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.18.12.1602"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc07-1238"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/00913847.1985.11708790"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.1.28"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1982.89"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.20.12.1814"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199107183250308"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8227(85)80034-6"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.1985.249.4.E360"},{"key":"e_1_2_8_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1983.tb09837.x"},{"key":"e_1_2_8_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.1989.tb01280.x"}],"container-title":["Diabetic Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1464-5491.2011.03380.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1464-5491.2011.03380.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T21:49:57Z","timestamp":1697406597000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1464-5491.2011.03380.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12,7]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["10.1111\/j.1464-5491.2011.03380.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1464-5491.2011.03380.x","archive":["Portico"],"relation":{},"ISSN":["0742-3071","1464-5491"],"issn-type":[{"value":"0742-3071","type":"print"},{"value":"1464-5491","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,12,7]]},"assertion":[{"value":"2011-12-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}