{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T16:31:25Z","timestamp":1784478685942,"version":"3.55.0"},"reference-count":34,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,1,11]],"date-time":"2012-01-11T00:00:00Z","timestamp":1326240000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetic Medicine"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:sec><jats:label\/><jats:p>Diabet. Med. 29, 198\u2013206 (2012)<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aims\u2003<\/jats:bold> The aim was to evaluate treatment goal achievements early in the course of Type\u20032 diabetes, and their effect on 10\u2010year risk of coronary heart disease in patients receiving usual care.<\/jats:p><jats:p><jats:bold>Methods\u2003<\/jats:bold> Assessment of risk factor control 3\u2003years after diagnosis in patients with Type\u20032 diabetes with no previous coronary heart disease included from the Swedish National Diabetes Register; a total of 19\u2003382 patients (mean age 58\u2003years) in cross\u2010sectional surveys from 2003 to 2008, and a subgroup of 4293 patients followed individually from year of diagnosis to follow\u2010up after a mean 2.6\u2003years. Estimation of absolute 10\u2010year risk of coronary heart disease using the UK Prospective Diabetes Study risk engine, and modifiable 10\u2010year risk defined as percentage excess risk above patients with \u2018normal\u2019 risk factor values.<\/jats:p><jats:p><jats:bold>Results\u2003<\/jats:bold> Treatment goals for HbA<jats:sub>1c<\/jats:sub>, blood pressure, total and LDL cholesterol were achieved in 78.4, 65.5, 55.6% and 61.0%, respectively, in the cross\u2010sectional survey in 2008, following a trend of generally improved control. In the individually followed patients in the subgroup, mean absolute 10\u2010year coronary heart disease risk increased from 13.7% (men\/women 16.9\/9.5%) to 14.2 (men\/women 17.6\/9.6%) (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.001) from year of diagnosis to follow\u2010up after 2.6\u2003years, while mean modifiable risk decreased from 37.7% (men\/women 28.6\/49.9%) to 19.1% (13.2\/26.9%) (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.001 in all).<\/jats:p><jats:p><jats:bold>Conclusions\u2003<\/jats:bold> A high achievement of treatment goals and a low mean modifiable 10\u2010year coronary heart disease risk was found at the 3\u2010year follow\u2010up, both in the cross\u2010sectional survey in 2008 and in patients individually followed since diagnosis. This indicates the feasibility and significance of early multifactorial risk factor treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1464-5491.2011.03425.x","type":"journal-article","created":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T03:51:03Z","timestamp":1314849063000},"page":"198-206","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Time trends in absolute and modifiable coronary heart disease risk in patients with Type\u20032 diabetes in the Swedish National Diabetes Register (NDR) 2003\u20132008"],"prefix":"10.1111","volume":"29","author":[{"given":"E.","family":"Fh\u00e4rm","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Cederholm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Eliasson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Gudbj\u00f6rnsdottir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Rolandsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,1,11]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.21.4.539"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.19.2570"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60697-8"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-009-1470-0"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200211000-00001"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0806470"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.12.1410"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0806359"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60104-X"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0706245"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.26.4.1270"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2008.02633.x"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2003.024802"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2008.103556"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2005.01648.x"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-668X(03)00347-6"},{"key":"e_1_2_7_18_2","unstructured":"Medical Products Agency.Prevention of atherosclerotic cardiovascular disease.2006(Swedish online treatment recommendations). 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